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Stress-associated endoplasmic reticulum protein 1 (SERP1) and Atg8 synergistically regulate unfolded protein response (UPR) that is independent on autophagy in Candida albicans.

Authors: Li Jianrong，Yu Qilin，Zhang Bing，Xiao Chenpeng，Ma Tianyu，Yi Xiao，Liang Chao，Li Ming

Journal: Int. J. Med. Microbiol.

PubMed ID: 29544880

Doi: 10.1016/j.ijmm.2018.03.004

Products & Services: Recombinant Proteins

Antitumor Activity of DLX1008， an Anti-VEGFA Antibody Fragment with Low Picomolar Affinity， in Human Glioma Models.

Authors: Szabó Emese，Phillips Douglas J，Droste Miriam，Marti Andrea，Kretzschmar Titus，Shamshiev Abdijapar，Weller Mic

Journal: J. Pharmacol. Exp. Ther.

PubMed ID: 29507055

Doi: 10.1124/jpet.117.246249

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Genome editing and transcriptional repression in Pseudomonas putida KT2440 via the type II CRISPR system.

Authors: Sun Jun，Wang Qingzhuo，Jiang Yu，Wen Zhiqiang，Yang Lirong，Wu Jianping，Yang S

Journal: Microb. Cell Fact.

PubMed ID: 29534717

Doi: 10.1186/s12934-018-0887-x

Products & Services: Recombinant Proteins

Tryptophan-Mediated Interactions between Tristetraprolin and the CNOT9 Subunit Are Required for CCR4-NOT Deadenylase Complex Recruitment.

Authors: Bulbrook D，Brazier H，Mahajan P，Kliszczak M，Fedorov O，Marchese F P，Aubareda A，Chalk R，Picaud S，Strain-Damerell C，Filippakopoulos P，Gileadi O，Clark A R，Yue W W，Burgess-Brown N A，Dean J

Journal: J. Mol. Biol.

PubMed ID: 29291391

Doi: 10.1016/j.jmb.2017.12.018

Products & Services: Recombinant Proteins

TRAIL induces apoptosis but not necroptosis in colorectal and pancreatic cancer cells preferentially via the TRAIL-R2/DR5 receptor.

Authors: Nahacka Zuzana，Svadlenka Jan，Peterka Martin，Ksandrova Marie，Benesova Simona，Neuzil Jiri，Andera Ladi

Journal: Biochim Biophys Acta Mol Cell Res

PubMed ID: 29278689

Doi: 10.1016/j.bbamcr.2017.12.006

Products & Services: Recombinant Proteins

Human antibody-based chemically induced dimerizers for cell therapeutic applications.

Authors: Hill Zachary B，Martinko Alexander J，Nguyen Duy P，Wells Jam

Journal: Nat. Chem. Biol.

PubMed ID: 29200207

Doi: 10.1038/nchembio.2529

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Hedgehog-YAP Signaling Pathway Regulates Glutaminolysis to Control Activation of Hepatic Stellate Cells.

Authors: DuKuo，HyunJeongeun，PremontRichard T，ChoiSteve S，MichelottiGregory A，Swiderska-SynMarzena，DaltonGeorge D，ThelenEric，RiziBahar Salimian，JungYoungmi，DiehlAnna

Journal: Gastroenterology

PubMed ID: 29305935

Doi: 10.1053/j.gastro.2017.12.022

Products & Services: Recombinant Proteins

Production of a germline-humanized cetuximab scFv and evaluation of its activity in recognizing EGFR- overexpressing cancer cells.

Authors: BanisadrArsham，SafdariYaghoub，KianmehrAnvarsadat，PourafsharMah

Journal: Hum Vaccin Immunother

PubMed ID: 29185855

Doi: 10.1080/21645515.2017.1407482

Products & Services: Recombinant Proteins

Design and synthesis of gallocyanine inhibitors of DKK1/LRP6 interactions for treatment of Alzheimer's disease.

Authors: ThysiadisSavvas，KatsamakasSotirios，MpousisSpyros，AvramidisNicolaos，EfthimiopoulosSpiros，SarliVasi

Journal: Bioorg. Chem.

PubMed ID: 29966869

Doi: 10.1016/j.bioorg.2018.06.018

Products & Services: Recombinant Proteins

Structural Basis of Phosphatidic Acid Sensing by APH in Apicomplexan Parasites.

Authors: DarvillNick，DuboisDavid J，RouseSarah L，HammoudiPierre-Mehdi，BlakeTom，BenjaminStefi，LiuBing，Soldati-FavreDominique，MatthewsS

Journal: Structure

PubMed ID: 29910186

Doi: 10.1016/j.str.2018.05.001

Products & Services: Recombinant Proteins