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Structural basis for receptor selectivity and inverse agonism in S1P receptors

Authors: Elizaveta Lyapina, Egor Marin, Anastasiia Gusach, Philipp Orekhov, Andrey Gerasimov, Aleksandra Luginina, Daniil Vakhrameev, Margarita Ergasheva, Margarita Kovaleva, Georgii Khusainov, Polina Khorn, Mikhail Shevtsov, Kirill Kovalev, Sergey Bukhdruker, Ivan Okhrimenko, Petr Popov, Hao Hu, Uwe Weierstall, Wei Liu, Yunje Cho, Ivan Gushchin, Andrey Rogachev, Gleb Bourenkov, Sehan Park, Gisu Park, Hyo Jung Hyun, Jaehyun Park, Valentin Gordeliy, Valentin Borshchevskiy, Alexey Mishin, Vadim Cherezov

Journal: Nat Commun

PubMed ID: 35961984

Doi: 10.1038/s41467-022-32447-1

Products & Services: Mammalian Expression

PTPRO knockdown protects against inflammation in hemorrhage shock-induced lung injury involving the NF-κB signaling pathway

Authors: Zhirong Huan, Ying Tang, Ce Xu, Jimin Cai, Hao Yao, Yan Wang, Fanyu Bu, Xin Ge

Journal: Respir Res

PubMed ID: 35906634

Doi: 10.1186/s12931-022-02118-2

Products & Services: Mammalian Expression

Impact of the temperature on the interactions between common variants of the SARS-CoV-2 receptor binding domain and the human ACE2

Authors: Catherine Forest-Nault, Izel Koyuturk, Jimmy Gaudreault, Alex Pelletier, Denis L'Abbé, Brian Cass, Louis Bisson, Alina Burlacu, Laurence Delafosse, Matthew Stuible, Olivier Henry, Gregory De Crescenzo, Yves Durocher

Journal: Sci Rep

PubMed ID: 35798770

Doi: 10.1038/s41598-022-15215-5

Products & Services: Mammalian Expression

Golgin Subfamily A Member 5 Is Essential for Production of Extracellular Matrix Proteins during TGF-1-Induced Periodontal Ligament-Fibroblastic Differentiation

Authors: Hyun-Jin Kim, Seong-Min Kim, Min-Jeong Choi, Young-Joo Jang

Journal: Stem Cells Int

PubMed ID: 35879965

Doi: 10.1155/2022/3273779

Products & Services: Mammalian Expression

CaMKII Inhibition Attenuates Distinct Gain-of-Function Effects Produced by Mutant Nav16 Channels and Reduces Neuronal Excitability

Authors: Agnes S Zybura, Firoj K Sahoo, Andy Hudmon, Theodore R Cummins

Journal: Cells

PubMed ID: 35805192

Doi: 10.3390/cells11132108

Products & Services: Mammalian Expression

Masking the immunotoxicity of interleukin-12 by fusing it with a domain of its receptor via a tumour-protease-cleavable linker

Authors: Aslan Mansurov , Peyman Hosseinchi, Kevin Chang, Abigail L Lauterbach, Laura T Gray , Aaron T Alpar , Erica Budina , Anna J Slezak , Seounghun Kang, Shijie Cao, Ani Solanki , Suzana Gomes , John-Michael Williford, Melody A Swartz , Juan L Mendoza , Jun Ishihara , Jeffrey A Hubbell

Journal: Nat Biomed Eng

PubMed ID: 35534574

Doi: 10.1038/s41551-022-00888-0

Products & Services: Mammalian Expression

Developing and validating SARS-CoV-2 assays for nonhuman primate surveillance

Authors: JoAnn Yee, Amanda Carpenter, Peter Nham, Bryson Halley, Koen K A Van Rompay, Jeffrey Roberts

Journal: J Med Primatol

PubMed ID: 35794847

Doi: 10.1111/jmp.12604

Products & Services: Mammalian Expression

The Unfolded-Protein Response Triggers the Arthropod Immune Deficiency Pathway

Authors: Lindsay C Sidak-Loftis, Kristin L Rosche, Natasha Pence, Jessica K Ujczo, Joanna Hurtado, Elis A Fisk, Alan G Goodman, Susan M Noh, John W Peters, Dana K Shaw

Journal: MBio

PubMed ID: 35862781

Doi: 10.1128/mbio.00703-22

Products & Services: Mammalian Expression

Translating a Thin-Film Rehydration Method to Microfluidics for the Preparation of a SARS-CoV-2 DNA Vaccine: When Manufacturing Method Matters

Authors: Allegra Peletta, Eakachai Prompetchara, Kittipan Tharakhet, Papatsara Kaewpang, Supranee Buranapraditkun, Nongnaphat Yostrerat, Suwimon Manopwisedjaroen, Arunee Thitithanyanont, Jonathan Avaro, Leonard Krupnik, Antonia Neels, Kiat Ruxrungtham, Chutitorn Ketloy, Gerrit Borchard

Journal: Pharmaceutics

PubMed ID: 35890321

Doi: 10.3390/pharmaceutics14071427

Products & Services: Mammalian Expression

Intranasal administration of a live-attenuated recombinant newcastle disease virus expressing the SARS-CoV-2 Spike protein induces high neutralizing antibody levels and protects from experimental challenge infection in hamsters

Authors: Rik L de Swart, Olav S de Leeuw, Nadia Oreshkova, Nora M Gerhards, Irina C Albulescu, Sandra Vreman, José L Gonzales, Riks Maas, Frank J M van Kuppeveld, Peter Soema, Berend-Jan Bosch, Ben P H Peeters

Journal: Vaccine

PubMed ID: 35820941

Doi: 10.1016/j.vaccine.2022.07.005

Products & Services: Mammalian Expression