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PTPRO knockdown protects against inflammation in hemorrhage shock-induced lung injury involving the NF-κB signaling pathway

Authors: Zhirong Huan, Ying Tang, Ce Xu, Jimin Cai, Hao Yao, Yan Wang, Fanyu Bu, Xin Ge

Journal: Respir Res

PubMed ID: 35906634

Doi: 10.1186/s12931-022-02118-2

Products & Services: Mammalian Expression

Impact of the temperature on the interactions between common variants of the SARS-CoV-2 receptor binding domain and the human ACE2

Authors: Catherine Forest-Nault, Izel Koyuturk, Jimmy Gaudreault, Alex Pelletier, Denis L'Abbé, Brian Cass, Louis Bisson, Alina Burlacu, Laurence Delafosse, Matthew Stuible, Olivier Henry, Gregory De Crescenzo, Yves Durocher

Journal: Sci Rep

PubMed ID: 35798770

Doi: 10.1038/s41598-022-15215-5

Products & Services: Mammalian Expression

Masking the immunotoxicity of interleukin-12 by fusing it with a domain of its receptor via a tumour-protease-cleavable linker

Authors: Aslan Mansurov , Peyman Hosseinchi, Kevin Chang, Abigail L Lauterbach, Laura T Gray , Aaron T Alpar , Erica Budina , Anna J Slezak , Seounghun Kang, Shijie Cao, Ani Solanki , Suzana Gomes , John-Michael Williford, Melody A Swartz , Juan L Mendoza , Jun Ishihara , Jeffrey A Hubbell

Journal: Nat Biomed Eng

PubMed ID: 35534574

Doi: 10.1038/s41551-022-00888-0

Products & Services: Mammalian Expression

Developing and validating SARS-CoV-2 assays for nonhuman primate surveillance

Authors: JoAnn Yee, Amanda Carpenter, Peter Nham, Bryson Halley, Koen K A Van Rompay, Jeffrey Roberts

Journal: J Med Primatol

PubMed ID: 35794847

Doi: 10.1111/jmp.12604

Products & Services: Mammalian Expression

CaMKII Inhibition Attenuates Distinct Gain-of-Function Effects Produced by Mutant Nav16 Channels and Reduces Neuronal Excitability

Authors: Agnes S Zybura, Firoj K Sahoo, Andy Hudmon, Theodore R Cummins

Journal: Cells

PubMed ID: 35805192

Doi: 10.3390/cells11132108

Products & Services: Mammalian Expression

The Unfolded-Protein Response Triggers the Arthropod Immune Deficiency Pathway

Authors: Lindsay C Sidak-Loftis, Kristin L Rosche, Natasha Pence, Jessica K Ujczo, Joanna Hurtado, Elis A Fisk, Alan G Goodman, Susan M Noh, John W Peters, Dana K Shaw

Journal: MBio

PubMed ID: 35862781

Doi: 10.1128/mbio.00703-22

Products & Services: Mammalian Expression

The Relative Positioning of B and T Cell Epitopes Drives Immunodominance

Authors: Riccardo Biavasco, Marco De Giovanni

Journal: Vaccines (Basel)

PubMed ID: 36016115

Doi: 10.3390/vaccines10081227

Products & Services: Mammalian Expression

Crystal structure of human NADK2 reveals a dimeric organization and active site occlusion by lysine acetylation

Authors: Charline Mary, Mona Hoseini Soflaee, Rushendhiran Kesavan, Muriel Gelin, Harrison Brown, G Zacharias, Thomas P Mathews, Andrew Lemoff, Corinne Lionne, Gilles Labesse, Gerta Hoxhaj

Journal: Mol Cell

PubMed ID: 35868311

Doi: 10.1016/j.molcel.2022.06.026

Products & Services: Mammalian Expression

Intranasal administration of a live-attenuated recombinant newcastle disease virus expressing the SARS-CoV-2 Spike protein induces high neutralizing antibody levels and protects from experimental challenge infection in hamsters

Authors: Rik L de Swart, Olav S de Leeuw, Nadia Oreshkova, Nora M Gerhards, Irina C Albulescu, Sandra Vreman, José L Gonzales, Riks Maas, Frank J M van Kuppeveld, Peter Soema, Berend-Jan Bosch, Ben P H Peeters

Journal: Vaccine

PubMed ID: 35820941

Doi: 10.1016/j.vaccine.2022.07.005

Products & Services: Mammalian Expression

Translating a Thin-Film Rehydration Method to Microfluidics for the Preparation of a SARS-CoV-2 DNA Vaccine: When Manufacturing Method Matters

Authors: Allegra Peletta, Eakachai Prompetchara, Kittipan Tharakhet, Papatsara Kaewpang, Supranee Buranapraditkun, Nongnaphat Yostrerat, Suwimon Manopwisedjaroen, Arunee Thitithanyanont, Jonathan Avaro, Leonard Krupnik, Antonia Neels, Kiat Ruxrungtham, Chutitorn Ketloy, Gerrit Borchard

Journal: Pharmaceutics

PubMed ID: 35890321

Doi: 10.3390/pharmaceutics14071427

Products & Services: Mammalian Expression

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