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Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies

Authors: Charles D Murin, Pavlo Gilchuk, Philipp A Ilinykh, Kai Huang, Natalia Kuzmina, Xiaoli Shen, Jessica F Bruhn, Aubrey L Bryan, Edgar Davidson, Benjamin J Doranz, Lauren E Williamson, Jeffrey Copps, Tanwee Alkutkar, Andrew I Flyak, Alexander Bukreyev, James E Crowe, Andrew B Ward

Journal: Cell Rep

PubMed ID: 33852862

Doi: 10.1016/j.celrep.2021.108984

Products & Services: Mammalian Expression

Secretion of bispecific protein of anti-PD-1 fused with TGF-β trap enhances antitumor efficacy of CAR-T cell therapy

Authors: Xianhui Chen, Shuai Yang, Si Li, Yun Qu, Hsuan-Yao Wang, Jiangyue Liu, Zachary S Dunn, Gunce E Cinay, Melanie A MacMullan, Fangheng Hu, Xiaoyang Zhang, Pin Wang

Journal: Mol Ther Oncolytics

PubMed ID: 33981830

Doi: 10.1016/j.omto.2021.03.014

Products & Services: Mammalian Expression

Modular basis for potent SARS-CoV-2 neutralization by a prevalent VH1-2-derived antibody class

Authors: Micah Rapp, Yicheng Guo, Eswar R Reddem, Jian Yu, Lihong Liu, Pengfei Wang, Gabriele Cerutti, Phinikoula Katsamba, Jude S Bimela, Fabiana A Bahna, Seetha M Mannepalli, Baoshan Zhang, Peter D Kwong, Yaoxing Huang, David D Ho, Lawrence Shapiro, Zizhang Sheng

Journal: Cell Rep

PubMed ID: 33794145

Doi: 10.1016/j.celrep.2021.108950

Products & Services: Mammalian Expression

Correction of β-thalassemia by CRISPR/Cas9 editing of the α-globin locus in human hematopoietic stem cells

Authors: Giulia Pavani, Anna Fabiano, Marine Laurent, Fatima Amor, Erika Cantelli, Anne Chalumeau, Giulia Maule, Alexandra Tachtsidi, Jean-Paul Concordet, Anna Cereseto, Fulvio Mavilio, Giuliana Ferrari, Annarita Miccio, Mario Amendola

Journal: Blood Adv

PubMed ID: 33635334

Doi: 10.1182/bloodadvances.2020001996

Products & Services: Mammalian Expression

Polymorphic SERPINA3 prolongs oligomeric state of amyloid beta

Authors: Maruf Mohammad Akbor, Nobuyuki Kurosawa, Hiroki Nakayama, Ayumi Nakatani, Koji Tomobe, Yoichi Chiba, Masaki Ueno, Masashi Tanaka, Yasuyuki Nomura, Masaharu Isobe

Journal: PLoS ONE

PubMed ID: 33662018

Doi: 10.1371/journal.pone.0248027

Products & Services: Mammalian Expression

Neuronal junctophilins recruit specific Ca and RyR isoforms to ER-PM junctions and functionally alter Ca21 and Ca22

Authors: Stefano Perni, Kurt Beam

Journal: Elife

PubMed ID: 33769283

Doi: 10.7554/eLife.64249

Products & Services: Mammalian Expression

Development of Spike Receptor-Binding Domain Nanoparticles as a Vaccine Candidate against SARS-CoV-2 Infection in Ferrets

Authors: Young-Il Kim, Dokyun Kim, Kwang-Min Yu, Hogyu David Seo, Shin-Ae Lee, Mark Anthony B Casel, Seung-Gyu Jang, Stephanie Kim, WooRam Jung, Chih-Jen Lai, Young Ki Choi, Jae U Jung

Journal: MBio

PubMed ID: 33653891

Doi: 10.1128/mBio.00230-21

Products & Services: Mammalian Expression

Brevetoxin and Conotoxin Interactions with Single-Domain Voltage-Gated Sodium Channels from a Diatom and Coccolithophore

Authors: Ping Yates, Julie A Koester, Alison R Taylor

Journal: Mar Drugs

PubMed ID: 33801270

Doi: 10.3390/md19030140

Products & Services: Mammalian Expression

A first exon termination checkpoint preferentially suppresses extragenic transcription

Authors: Liv M I Austenaa, Viviana Piccolo, Marta Russo, Elena Prosperini, Sara Polletti, Danilo Polizzese, Serena Ghisletti, Iros Barozzi, Giuseppe R Diaferia, Gioacchino Natoli

Journal: Nat Struct Mol Biol

PubMed ID: 33767452

Doi: 10.1038/s41594-021-00572-y

Products & Services: Mammalian Expression

Functional expression of complement factor I following AAV-mediated gene delivery in the retina of mice and human cells

Authors: Anna K Dreismann, Michelle E McClements, Alun R Barnard, Elise Orhan, Jane P Hughes, Peter J Lachmann, Robert E MacLaren

Journal: Gene Ther

PubMed ID: 33750925

Doi: 10.1038/s41434-021-00239-9

Products & Services: Mammalian Expression