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Long noncoding RNA-mediated activation of PROTOR1/PRR5-AKT signaling shunt downstream of PI3K in triple-negative breast cancer

Authors: Zhenbo Tu, Yi Hu, Devesh Raizada, Mahmoud A Bassal, Daniel G Tenen, Antoine E Karnoub

Journal: Proc Natl Acad Sci U S A

PubMed ID: 36269860

Doi: 10.1073/pnas.2203180119

Products & Services: Mammalian Expression

DNA damage-induced nuclear import of HSP90α is promoted by Aha1

Authors: Nupur Fangaria, Khushboo Rani, Priyanka Singh, Sandeep Dey, Kota Arun Kumar, Sunanda Bhattacharyya

Journal: Mol Biol Cell

PubMed ID: 36260391

Doi: 10.1091/mbc.E21-11-0554

Products & Services: Mammalian Expression

Structural basis of interleukin-17B receptor in complex with a neutralizing antibody for guiding humanization and affinity maturation

Authors: Wen-Hsin Lee, Xiaorui Chen, I-Ju Liu, Jiin-Horng Lee, Chun-Mei Hu, Han-Chung Wu, Sheng-Kai Wang, Wen-Hwa Lee, Che Ma

Journal: Cell Rep

PubMed ID: 36288706

Doi: 10.1016/j.celrep.2022.111555

Products & Services: Mammalian Expression

An arrayed genome-wide perturbation screen identifies the ribonucleoprotein Hnrnpk as rate-limiting for prion propagation

Authors: Merve Avar, Daniel Heinzer, Alana M Thackray, Yingjun Liu, Marian Hruska-Plochan, Stefano Sellitto, Elke Schaper, Daniel P Pease, Jiang-An Yin, Asvin Kk Lakkaraju, Marc Emmenegger, Marco Losa, Andra Chincisan, Simone Hornemann, Magdalini Polymenidou, Raymond Bujdoso, Adriano Aguzzi

Journal: EMBO J

PubMed ID: 36254605

Doi: 10.15252/embj.2022112338

Products & Services: Mammalian Expression

Priming conditions shape breadth of neutralizing antibody responses to sarbecoviruses

Authors: Janice Zhirong Jia, Chee Wah Tan, Samuel M S Cheng, Haogao Gu, Aileen Ying Yan Yeoh, Chris Ka Pun Mok, Yanqun Wang, Jincun Zhao, Nancy H L Leung, Benjamin J Cowling, Leo L M Poon, David S C Hui, Linfa Wang, Malik Peiris, Sophie A Valkenburg

Journal: Nat Commun

PubMed ID: 36271047

Doi: 10.1038/s41467-022-34038-6

Products & Services: Mammalian Expression

Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion

Authors: Palak N Patel, Thayne H Dickey, Christine S Hopp, Ababacar Diouf, Wai Kwan Tang, Carole A Long, Kazutoyo Miura, Peter D Crompton, Niraj H Tolia

Journal: Nat Commun

PubMed ID: 36202833

Doi: 10.1038/s41467-022-33336-3

Products & Services: Mammalian Expression

Construction of a bioluminescence-based assay for bitter taste receptors (TAS2Rs)

Authors: Shi Min Tan, Wei-Guang Seetoh

Journal: Sci Rep

PubMed ID: 36271274

Doi: 10.1038/s41598-022-21678-3

Products & Services: Mammalian Expression

The choroid plexus: a door between the blood and the brain for tissue-type plasminogen activator

Authors: Vincent Zuba, Jonathane Furon, Mathys Bellemain-Sagnard, Sara Martinez de Lizarrondo, Laurent Lebouvier, Marina Rubio, Yannick Hommet, Maxime Gauberti, Denis Vivien, Carine Ali

Journal: Fluids Barriers CNS

PubMed ID: 36243724

Doi: 10.1186/s12987-022-00378-0

Products & Services: Mammalian Expression

Proteomic identification and structural basis for the interaction between sorting nexin SNX17 and PDLIM family proteins

Authors: Michael D Healy, Joanna Sacharz, Kerrie E McNally, Calum McConville, Vikas A Tillu, Ryan J Hall, Molly Chilton, Peter J Cullen, Mehdi Mobli, Rajesh Ghai, David A Stroud, Brett M Collins

Journal: Structure

PubMed ID: 36302387

Doi: 10.1016/j.str.2022.10.001

Products & Services: Mammalian Expression

Blocking Autophagy in M1 Macrophages Enhances Virus Replication and Eye Disease in Ocularly Infected Transgenic Mice

Authors: Ujjaldeep Jaggi, Harry H Matundan, Dhong Hyun Lee, Homayon Ghiasi

Journal: J Virol

PubMed ID: 36286481

Doi: 10.1128/jvi.01401-22

Products & Services: Mammalian Expression