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Structures of the junctophilin/voltage-gated calcium channel interface reveal hot spot for cardiomyopathy mutations

Authors: Zheng Fang Yang, Pankaj Panwar, Ciaran R McFarlane, Wietske E Tuinte, Marta Campiglio, Filip Van Petegem

Journal: Proc Natl Acad Sci U S A

PubMed ID: 35238659

Doi: 10.1073/pnas.2120416119

Products & Services: Mammalian Expression

Self-amplifying mRNA SARS-CoV-2 vaccines raise cross-reactive immune response to variants and prevent infection in animal models

Authors: Giuseppe Palladino, Cheng Chang, Changkeun Lee, Nedzad Music, Ivna De Souza, Jonathan Nolasco, Samuel Amoah, Pirada Suphaphiphat, Gillis R Otten, Ethan C Settembre, Yingxia Wen

Journal: Mol Ther Methods Clin Dev

PubMed ID: 35345593

Doi: 10.1016/j.omtm.2022.03.013

Products & Services: Mammalian Expression

A compact and simple method of achieving differential transgene expression by exploiting translational readthrough

Authors: James E Sillibourne, Giulia Agliardi, Matteo Righi, Katerina Smetanova, Grant Rowley, Simon Speller, Abigail Dolor, Katarina Lamb, Christopher Allen, Rajeev Karattil, Farhaan Parekh, Frederick Arce Vargas, Simon Thomas, Shaun Cordoba, Martin Pule

Journal: BioTechniques

PubMed ID: 35234525

Doi: 10.2144/btn-2021-0079

Products & Services: Mammalian Expression

A randomized clinical trial of a booster dose with low versus standard dose of AZD1222 in adult after 2 doses of inactivated vaccines

Authors: Sira Nanthapisal, Thanyawee Puthanakit, Peera Jaru-Ampornpan, Rapisa Nantanee, Pimpayao Sodsai, Orawan Himananto, Jiratchaya Sophonphan, Pintip Suchartlikitwong, Narin Hiransuthikul, Pornpimon Angkasekwinai, Auchara Tangsathapornpong, Nattiya Hirankarn

Journal: Vaccine

PubMed ID: 35341647

Doi: 10.1016/j.vaccine.2022.03.036

Products & Services: Mammalian Expression

Structural and functional analysis of the human cone-rod homeobox transcription factor

Authors: Penelope-Marie B Clanor, Christine N Buchholz, Jonathan E Hayes, Michael A Friedman, Andrew M White, Ray A Enke, Christopher E Berndsen

Journal: Proteins

PubMed ID: 35255174

Doi: 10.1002/prot.26332

Products & Services: Mammalian Expression

Protein Electrostatics Investigated through Paramagnetic NMR for Nonpolar Groups

Authors: Binhan Yu, Channing C Pletka, Junji Iwahara

Journal: J Phys Chem B

PubMed ID: 35266708

Doi: 10.1021/acs.jpcb.1c10930

Products & Services: Mammalian Expression

RACK1 Associates with RNA-Binding Proteins Vigilin and SERBP1 to Facilitate Dengue Virus Replication

Authors: Alexis Brugier, Mohamed Lamine Hafirrassou, Marie Pourcelot, Morgane Baldaccini, Vasiliya Kril, Laurine Couture, Beate M Kümmerer, Sarah Gallois-Montbrun, Lucie Bonnet-Madin, Pierre-Olivier Vidalain, Constance Delaugerre, Sébastien Pfeffer, Laurent Meertens, Ali Amara

Journal: J Virol

PubMed ID: 35266803

Doi: 10.1128/jvi.01962-21

Products & Services: Mammalian Expression

Fatty acid oxidation fuels glioblastoma radioresistance with CD47-mediated immune evasion

Authors: Nian Jiang, Bowen Xie, Wenwu Xiao, Ming Fan, Shanxiu Xu, Yixin Duan, Yamah Hamsafar, Angela C Evans, Jie Huang, Weibing Zhou, Xuelei Lin, Ningrong Ye, Siyi Wanggou, Wen Chen, Di Jing, Ruben C Fragoso, Brittany N Dugger, Paul F Wilson, Matthew A Coleman, Shuli Xia, Xuejun Li, Lun-Quan Sun, Arta M Monjazeb, Aijun Wang, William J Murphy, Hsing-Jien Kung, Kit S Lam, Hong-Wu Chen, Jian Jian Li

Journal: Nat Commun

PubMed ID: 35314680

Doi: 10.1038/s41467-022-29137-3

Products & Services: Mammalian Expression

The insecticide β-Cyfluthrin induces acute arrhythmic cardiotoxicity through interaction with NaV15 and ranolazine reverses the phenotype

Authors: Maria Vitoria da Silva, Artur Santos-Miranda, Julliane V Joviano-Santos, Diego Santos Souza, Leisiane Pereira Marques, Jaqueline Oliveira Sarmento, Samuel Santos Beserra, Danilo Roman-Campos

Journal: Clin Sci (Lond)

PubMed ID: 35190819

Doi: 10.1042/CS20211151

Products & Services: Mammalian Expression

Systemic and Lower Respiratory Tract Immunity to SARS-CoV-2 Omicron and Variants in Pediatric Severe COVID-19 and Mis-C

Authors: Juanjie Tang, Adrienne G Randolph, Tanya Novak, Tracie C Walker, Laura L Loftis, Matt S Zinter, Katherine Irby, Surender Khurana

Journal: Vaccines (Basel)

PubMed ID: 35214728

Doi: 10.3390/vaccines10020270

Products & Services: Mammalian Expression