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BMP4 overexpression induces the upregulation of APP/Tau and memory deficits in Alzheimer's disease

Authors: Xiaoqing Zhang, Juan Li, Li Ma, Hui Xu, Yun Cao, Wei Liang, Jia Ma, Z Peter Wang, Yuyun Li

Journal: Cell Death Discov

PubMed ID: 33723239

Doi: 10.1038/s41420-021-00435-x

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Identification of pathogenic variants in cancer genes using base editing screens with editing efficiency correction

Authors: Changcai Huang, Guangyu Li, Jiayu Wu, Junbo Liang, Xiaoyue Wang

Journal: Genome Biol

PubMed ID: 33691754

Doi: 10.1186/s13059-021-02305-2

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Targeted intestinal deletion of Rho guanine nucleotide exchange factor 7, βPIX, impairs enterocyte proliferation, villus maturation, and mucosal defenses in mice

Authors: Kunrong Cheng, Shannon M Larabee, Mazen Tolaymat, Marie Hanscom, Aaron C Shang, Alyssa Schledwitz, Shien Hu, Cinthia B Drachenberg, Min Zhan, Ahmed Chahdi, Jean-Pierre Raufman

Journal: Am J Physiol Gastrointest Liver Physiol

PubMed ID: 33566751

Doi: 10.1152/ajpgi.00415.2020

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5-Aminoisoquinolinone, a PARP-1 Inhibitor, Ameliorates Immune Abnormalities through Upregulation of Anti-Inflammatory and Downregulation of Inflammatory Parameters in T Cells of BTBR Mouse Model of Autism

Authors: Khaled Alhosaini, Mushtaq A Ansari, Ahmed Nadeem, Saleh A Bakheet, Sabry M Attia, Khalid Alhazzani, Thamer H Albekairi, Haneen A Al-Mazroua, Hafiz M Mahmood, Sheikh F Ahmad

Journal: Brain Sci

PubMed ID: 33671196

Doi: 10.3390/brainsci11020249

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Dysregulation of Ki-67 Expression in T Cells of Children with Autism Spectrum Disorder

Authors: Khaled Alhosaini, Mushtaq A Ansari, Ahmed Nadeem, Sabry M Attia, Saleh A Bakheet, Laila Y Al-Ayadhi, Hafiz M Mahmood, Haneen A Al-Mazroua, Sheikh F Ahmad

Journal: Children (Basel)

PubMed ID: 33562037

Doi: 10.3390/children8020116

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RPA-mediated recruitment of Bre1 couples histone H2B ubiquitination to DNA replication and repair

Authors: Guangxue Liu, Jiaqi Yan, Xuejie Wang, Junliang Chen, Xin Wang, Yang Dong, Simin Zhang, Xiaoli Gan, Jun Huang, Xuefeng Chen

Journal: Proc Natl Acad Sci U S A

PubMed ID: 33602814

Doi: 10.1073/pnas.2017497118

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CircRNA ZNF609 Knockdown Represses the Development of Non-Small Cell Lung Cancer via miR-623/FOXM1 Axis

Authors: Fanghan Wang, Xiangfeng Li, Xigao Jia, Luxin Geng

Journal: Cancer Manag Res

PubMed ID: 33574702

Doi: 10.2147/CMAR.S282162

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Curcumin Modulates the Crosstalk Between Macrophages and Bone Mesenchymal Stem Cells to Ameliorate Osteogenesis

Authors: Songfeng Chen, Hang Liang, Yanhui Ji, Hongwei Kou, Chi Zhang, Guowei Shang, Chunfeng Shang, Zongmian Song, Lin Yang, Lei Liu, Yongkui Wang, Hongjian Liu

Journal: Front Cell Dev Biol

PubMed ID: 33634135

Doi: 10.3389/fcell.2021.634650

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Impact of Excipients on Stability of Polymer Microparticles for Autoimmune Therapy

Authors: Emily A Gosselin, Maeesha Noshin, Sheneil K Black, Christopher M Jewell

Journal: Front Bioeng Biotechnol

PubMed ID: 33644005

Doi: 10.3389/fbioe.2020.609577

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Tracing DNA paths and RNA profiles in cultured cells and tissues with ORCA

Authors: Leslie J Mateo, Nasa Sinnott-Armstrong, Alistair N Boettiger

Journal: Nat Protoc

PubMed ID: 33619390

Doi: 10.1038/s41596-020-00478-x

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