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Multi-omic analysis of selectively vulnerable motor neuron subtypes implicates altered lipid metabolism in ALS

Authors: Hojae Lee, Jae Jin Lee, Na Young Park, Sandeep Kumar Dubey, Taeyong Kim, Kai Ruan, Su Bin Lim, Seong-Hyun Park, Shinwon Ha, Irina Kovlyagina, Kyung-Tai Kim, Seongjun Kim, Yohan Oh, Hyesoo Kim, Sung-Ung Kang, Mi-Ryoung Song, Thomas E Lloyd, Nicholas J Maragakis, Young Bin Hong, Hyungjin Eoh, Gabsang Lee

Journal: Nat Neurosci

PubMed ID: 34782793

Doi: 10.1038/s41593-021-00944-z

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SP-1154, a novel synthetic TGF-β inhibitor, alleviates obesity and hepatic steatosis in high-fat diet-induced mice

Authors: Kisoo Pahk, Sang Gil Lee, Chanmin Joung, Eun-Ok Kim, Hyun Woo Kwon, Dong Hwi Kim, Jong-Ik Hwang, Sungeun Kim, Won-Ki Kim

Journal: Biomed Pharmacother

PubMed ID: 34813997

Doi: 10.1016/j.biopha.2021.112441

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A Novel Serum tsRNA for Diagnosis and Prediction of Nephritis in SLE

Authors: Ping Yang, Xiaoshan Zhang, Shanshan Chen, Yue Tao, Mingzhe Ning, Yijia Zhu, Jun Liang, Wei Kong, Bo Shi, Zhiyang Li, Han Shen, Yanbo Wang

Journal: Front Immunol

PubMed ID: 34867955

Doi: 10.3389/fimmu.2021.735105

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Scaling DNA data storage with nanoscale electrode wells

Authors: Bichlien H Nguyen, Christopher N Takahashi, Gagan Gupta, Jake A Smith, Richard Rouse, Paul Berndt, Sergey Yekhanin, David P Ward, Siena D Ang, Patrick Garvan, Hsing-Yeh Parker, Rob Carlson, Douglas Carmean, Luis Ceze, Karin Strauss

Journal: Sci Adv

PubMed ID: 34818035

Doi: 10.1126/sciadv.abi6714

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A novel chimeric protein with enhanced cytotoxic effects on breast cancer in vitro and in vivo

Authors: Fereshte Hazrati, Massoud Saidijam, Yaghoub Ahmadyousefi, Fatemeh Nouri, Hamidreza Ghadimipour, Mohammadreza Moradi, Rasool Haddadi, Meysam Soleimani

Journal: Proteins

PubMed ID: 34812523

Doi: 10.1002/prot.26285

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Identification and evolutionary analysis of the metal-tolerance protein family in eight Cucurbitaceae species

Authors: Xinchen Jiang, Junliang Yin, Lixin Wang, Keyong Xi, Xiongmeng Zhu, Gang Li, Yongxing Zhu, Yiqing Liu

Journal: Plant Genome

PubMed ID: 34741493

Doi: 10.1002/tpg2.20167

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T cell receptor therapy targeting mutant capicua transcriptional repressor in experimental gliomas

Authors: Michael Kilian, Mirco Friedrich, Khwab Sanghvi, Edward Green, Stefan Pusch, Daisuke Kawauchi, Martin Löwer, Jana K Sonner, Christopher Krämer, Julia Zaman, Stefanie Jung, Michael O Breckwoldt, Gerald Willimksy, Stefan B Eichmüller, Andreas von Deimling, Wolfgang Wick, Felix Sahm, Michael Platten, Lukas Bunse

Journal: Clin Cancer Res

PubMed ID: 34782365

Doi: 10.1158/1078-0432.CCR-21-1881

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A simple PCR-RFLP method for identification and detection of medicinal toad and its crude drug even with serious degradation of DNA

Authors: Jiao Liu, Xinyi Shao, Ziying Zhou, Miao Lei, Mingyu Xia, Dong Wang

Journal: J Pharm Biomed Anal

PubMed ID: 34864355

Doi: 10.1016/j.jpba.2021.114495

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Protoplast isolation and transcriptome analysis of developing xylem in Pinus massoniana (Pinaceae)

Authors: Tengfei Shen, Mengxuan Xu, Haoran Qi, Yuanheng Feng, Zhangqi Yang, Meng Xu

Journal: Mol Biol Rep

PubMed ID: 34826048

Doi: 10.1007/s11033-021-06995-6

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Curcumol inhibits malignant biological behaviors and TMZ-resistance in glioma cells by inhibiting long noncoding RNA FOXD2-As1-promoted EZH2 activation

Authors: Xuyang Lv, Jiangchuan Sun, Linfeng Hu, Ying Qian, Chunlei Fan, Nan Tian

Journal: Aging (Albany NY)

PubMed ID: 34739394

Doi: 10.18632/aging.203662

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