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Structures of the ApoL1 and ApoL2 N-terminal domains reveal a non-classical four-helix bundle motif

Authors: Mark Ultsch, Michael J Holliday, Stefan Gerhardy, Paul Moran, Suzie J Scales, Nidhi Gupta, Francesca Oltrabella, Cecilia Chiu, Wayne Fairbrother, Charles Eigenbrot, Daniel Kirchhofer

Journal: Commun Biol

PubMed ID: 34316015

Doi: 10.1038/s42003-021-02387-5

Products & Services: DNA Sequencing

T cruzi DNA polymerase beta (Tcpolβ) is phosphorylated in vitro by CK1, CK2 and TcAUK1 leading to the potentiation of its DNA synthesis activity

Authors: Edio Maldonado, Diego A Rojas, Fabiola Urbina, Aldo Solari

Journal: PLoS Negl Trop Dis

PubMed ID: 34260580

Doi: 10.1371/journal.pntd.0009588

Products & Services: DNA Sequencing

RNA editing enzyme adenosine deaminases acting on RNA 1 deficiency increases the sensitivity of non-small cell lung cancer cells to anlotinib by regulating CX3CR1-fractalkine expression

Authors: Min Wu, Mengmeng Jin, Xiaohui Cao, Kun Qian, Lei Zhao

Journal: Drug Dev Res

PubMed ID: 34319598

Doi: 10.1002/ddr.21861

Products & Services: DNA Sequencing

Identification of a protein unique to the genus Plasmodium that contains a WD40 repeat domain and extensive low-complexity sequence

Authors: Gladys T Cortés, Martha Margarita Gonzalez Beltran, Claudio J Gómez-Alegría, Mark F Wiser

Journal: Parasitol Res

PubMed ID: 34142223

Doi: 10.1007/s00436-021-07190-z

Products & Services: DNA Sequencing

A sensitive and reproducible cell-based assay via secNanoLuc to detect neutralizing antibody against adeno-associated virus vector capsid

Authors: Nemekhbayar Baatartsogt, Yuji Kashiwakura, Morisada Hayakawa, Nobuhiko Kamoshita, Takafumi Hiramoto, Hiroaki Mizukami, Tsukasa Ohmori

Journal: Mol Ther Methods Clin Dev

PubMed ID: 34485602

Doi: 10.1016/j.omtm.2021.06.004

Products & Services: DNA Sequencing

Network Pharmacology Analysis of the Mechanisms of Compound Herba Sarcandrae (Fufang Zhongjiefeng) Aerosol in Chronic Pharyngitis Treatment

Authors: Yanping Zhang, Taohua Yuan, Yunsong Li, Ning Wu, Xiaotian Dai

Journal: Drug Des Devel Ther

PubMed ID: 34234411

Doi: 10.2147/DDDT.S304708

Products & Services: DNA Sequencing

Human GPR17 missense variants identified in metabolic disease patients have distinct downstream signaling profiles

Authors: Jason M Conley, Hongmao Sun, Kristin L Ayers, Hu Zhu, Rong Chen, Min Shen, Matthew D Hall, Hongxia Ren

Journal: J Biol Chem

PubMed ID: 34144038

Doi: 10.1016/j.jbc.2021.100881

Products & Services: DNA Sequencing

Targeting the Extracellular HSP90 Co-Chaperone Morgana Inhibits Cancer Cell Migration and Promotes Anticancer Immunity

Authors: Laura Seclì, Lidia Avalle, Pietro Poggio, Giuseppe Fragale, Cristiana Cannata, Laura Conti, Andrea Iannucci, Giovanna Carrà, Cristina Rubinetto, Barbara Miniscalco, Emilio Hirsch, Valeria Poli, Alessandro Morotti, Marco De Andrea, Emilia Turco, Federica Cavallo, Federica Fusella, Mara Brancaccio

Journal: Cancer Res

PubMed ID: 34193441

Doi: 10.1158/0008-5472.CAN-20-3150

Products & Services: DNA Sequencing

Identification of a T-bet Quiescent Exhausted CD8 T Cell Subpopulation That Can Differentiate into TIM3CX3CR1 Effectors and Memory-like Cells

Authors: Saravanan Raju, Yu Xia, Bence Daniel, Kathryn E Yost, Elliot Bradshaw, Elena Tonc, Daniel J Verbaro, Kohei Kometani, Wayne M Yokoyama, Tomohiro Kurosaki, Ansuman T Satpathy, Takeshi Egawa

Journal: J Immunol

PubMed ID: 34088768

Doi: 10.4049/jimmunol.2001348

Products & Services: DNA Sequencing

YTHDF2 inhibit the tumorigenicity of endometrial cancer via downregulating the expression of IRS1 methylated with mA

Authors: Ling Hong, Xiaowen Pu, Haili Gan, Lichun Weng, Qingliang Zheng

Journal: J Cancer

PubMed ID: 34093789

Doi: 10.7150/jca.54527

Products & Services: DNA Sequencing