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Oncolytic adenoviral delivery of an EGFR-targeting T-cell engager improves antitumor efficacy

Authors: Carlos Alberto Fajardo , Sonia Guedan , Luis Alfonso Rojas , Rafael Moreno , Marcel Arias-Badia , Jana de Sostoa , Carl H. June , and Ramon Alemany

Journal: American Association for Cancer Research.

Doi: 10.1158/0008-5472.CAN-16-1708

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Influenza virus genome reaches the plasma membrane via a modified endoplasmic reticulum and Rab11-dependent vesicles

Authors: Isabel Fernández de Castro Martin, Guillaume Fournier, Martin Sachse, Javier Pizarro-Cerda, Cristina Risco & Nadia Naffakh

Journal: Nature Communications

Doi: 10.1128/JVI.01179-17

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Regulating unfolded protein response activator HAC1p for production of thermostable raw-starch hydrolyzing α-amylase in Pichia pastoris.

Authors: Huang M, Gao Y, Zhou X, Zhang Y,, Cai M.

Journal: Bioprocess Biosyst Eng

PubMed ID: 27796570

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Crystal Structure of the Minimal Cas9 from Campylobacter jejuni Reveals the Molecular Diversity in the CRISPR-Cas9 Systems.

Authors: Yamada M, Watanabe Y, Gootenberg JS, Hirano H, Ran FA, Nakane T, Ishitani R, Zhang F, Nishimasu H, Nureki O.

Journal: Mol Cell

PubMed ID: 28306506

Doi: 10.1016/j.molcel.2017.02.007

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SENP7 Potentiates cGAS Activation by Relieving SUMO-Mediated Inhibition of Cytosolic DNA Sensing.

Authors: Cui Y, Yu H, Zheng X, Peng R, Wang Q, Zhou Y, Wang R, Wang J, Qu B, Shen N, Guo Q, Liu X, Wang C,.

Journal: PLoS Pathog

PubMed ID: 28095500

Doi: 10.1371/journal.ppat.1006156

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Engineering a Multifunctional Nitroreductase for Improved Activation of Prodrugs and PET Probes for Cancer Gene Therapy.

Authors: Copp JN, Mowday AM, Williams EM, Guise CP, Ashoorzadeh A, Sharrock AV, Flanagan JU, Smaill JB, Patterson AV, Ackerley DF.

Journal: Cell Chem Biol

PubMed ID: 28262557

Doi: 10.1016/j.chembiol.2017.02.005

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DNA binding by PHF1 prolongs PRC2 residence time on chromatin and thereby promotes H3K27 methylation.

Authors: Choi Jeongyoon，Bachmann Andreas Linus，Tauscher Katharina，Benda Christian，Fierz Beat，Müller J

Journal: Nat. Struct. Mol. Biol.

PubMed ID: 29058710

Doi: 10.1038/nsmb.3488

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Engineering Saccharomyces cerevisiae for Efficient Biosynthesis of Fatty Alcohols Based on Enhanced Supply of Free Fatty Acids.

Authors: Tang X,, Feng L, Chen L, Chen WN.

Journal: ACS Omega

PubMed ID: 30023691

Doi: 10.1021/acsomega.7b00065

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A viral protein antibiotic inhibits lipid II flippase activity.

Authors: Chamakura KR, Sham LT, Davis RM, Min L, Cho H, Ruiz N, Bernhardt TG, Young R.

Journal: Nat Microbiol

PubMed ID: 28894177

Doi: 10.1038/s41564-017-0023-4

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Architecture and mechanism of the late endosomal Rab7-like Ypt7 guanine nucleotide exchange factor complex Mon1-Ccz1.

Authors: Kiontke Stephan，Langemeyer Lars，Kuhlee Anne，Schuback Saskia，Raunser Stefan，Ungermann Christian，Kümmel Da

Journal: Nat Commun

PubMed ID: 28051187

Doi: 10.1038/ncomms14034

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