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Regulated secretion of mutant p53 negatively affects T lymphocytes in the tumor microenvironment

Authors: Xiang Dong, Chunlu Li, Chengsi Deng, Jingwei Liu, Danni Li, Tingting Zhou, Xindi Yang, Yunchan Liu, Qiqiang Guo, Yanling Feng, Yang Yu, Zhuo Wang, Wendong Guo, Siyi Zhang, Hongyan Cui, Cui Jiang, Xiwen Wang, Xiaoyu Song, Xun Sun, Liu Cao

Journal: Oncogene

PubMed ID: 37952080

Doi: 10.1038/s41388-023-02886-1

Products & Services: Protein and Antibody Isolation

Extracellular and intracellular destruction of Pseudomonas aeruginosa by Dictyostelium discoideum phagocytes mobilize different antibacterial mechanisms

Authors: Imen Ayadi, Otmane Lamrabet, Raphael Munoz-Ruiz, Tania Jauslin, Cyril Guilhen, Pierre Cosson

Journal: Mol Microbiol

PubMed ID: 38017607

Doi: 10.1111/mmi.15197

Products & Services: Protein and Antibody Isolation

Molecular basis for the catalytic mechanism of human neutral sphingomyelinases 1 (hSMPD2)

Authors: Jingbo Yi, Boya Qi, Jian Yin, Ruochong Li, Xudong Chen, Junhan Hu, Guohui Li, Sensen Zhang, Yuebin Zhang, Maojun Yang

Journal: Nat Commun

PubMed ID: 38012235

Doi: 10.1038/s41467-023-43580-w

Products & Services: Protein and Antibody Isolation

Development of an Electrochemical, Aptamer-Based Sensor for Dynamic Detection of Neuropeptide Y

Authors: Jordan M Seibold, Sanduni W Abeykoon, Ashley E Ross, Ryan J White

Journal: ACS Sens

PubMed ID: 38033269

Doi: 10.1021/acssensors.3c00855

Products & Services: Recombinant Proteins

Environment relevant exposure of perfluorooctanoic acid accelerates the growth of hepatocellular carcinoma cells through mammalian target of rapamycin (mTOR) signal pathway

Authors: Jiawei Hong, Xiaoyan Wang, Hangbiao Jin, Yuanchen Chen, Yifan Jiang, Keyi Du, Diyu Chen, Shusen Zheng, Linping Cao

Journal: Environ Pollut

PubMed ID: 37967710

Doi: 10.1016/j.envpol.2023.122910

Products & Services: Protein Electrophoresis and Western

The Peroxidase gene OsPrx114 Activated by OsWRKY50 Enhances Drought Tolerance through ROS Scavenging in Rice

Authors: Chao Zheng , Xuming Wang , Yue Xu , Shaomin Wang , Xin Jiang e , Xiuli Liub , Weijun Cui , Yueyan Wu , Chengqi Yan , Hongjia Liu , Yin Lu e, Jianping Chen a,b, and Jie Zhou

Journal: Plant Physiology and Biochemistry

Doi: 10.1016/j.plaphy.2023.108138

Products & Services: Protein and Antibody Isolation

Engineered immunogens to elicit antibodies against conserved coronavirus epitopes

Authors: A Brenda Kapingidza, Daniel J Marston, Caitlin Harris, Daniel Wrapp, Kaitlyn Winters, Dieter Mielke, Lu Xiaozhi, Qi Yin, Andrew Foulger, Rob Parks, Maggie Barr, Amanda Newman, Alexandra Schäfer, Amanda Eaton, Justine Mae Flores, Austin Harner, Nicholas J Catanzaro, Michael L Mallory, Melissa D Mattocks, Christopher Beverly, Brianna Rhodes, Katayoun Mansouri, Elizabeth Van Itallie, Pranay Vure, Brooke Dunn, Taylor Keyes, Sherry Stanfield-Oakley, Christopher W Woods, Elizabeth A Petzold, Emmanuel B Walter, Kevin Wiehe, Robert J Edwards, David C Montefiori, Guido Ferrari, Ralph Baric, Derek W Cain, Kevin O Saunders, Barton F Haynes, Mihai L Azoitei

Journal: Nat Commun

PubMed ID: 38036525

Doi: 10.1038/s41467-023-43638-9

Products & Services: Protein and Antibody Isolation

Engineered IL-7 synergizes with IL-12 immunotherapy to prevent T cell exhaustion and promote memory without exacerbating toxicity

Authors: Seounghun Kang, Aslan Mansurov, Trevin Kurtanich, Hye Rin Chun, Anna J Slezak, Lisa R Volpatti, Kevin Chang, Thomas Wang, Aaron T Alpar, Kirsten C Refvik, O Isabella Hansen, Gustavo J Borjas, Ha-Na Shim, Kevin T Hultgren, Suzana Gomes, Ani Solanki, Jun Ishihara, Melody A Swartz, Jeffrey A Hubbell

Journal: Sci Adv

PubMed ID: 38019919

Doi: 10.1126/sciadv.adh9879

Products & Services: Protein and Antibody Isolation

Role and mechanism of miR-871-3p/Megf8 in regulating formaldehyde-induced cardiomyocyte inflammation and congenital heart disease

Authors: Xiaoli Yuan, Rui Chen, Gang Luo, Pin Sun, Xiaoxia Song, Jianmin Ma, Ruicong Sun, Tao Yu, Zhirong Jiang

Journal: Int Immunopharmacol

PubMed ID: 38039718

Doi: 10.1016/j.intimp.2023.111297

Products & Services: Protein and Antibody Isolation

Exosome-targeted delivery of METTL14 regulates NFATc1 m6A methylation levels to correct osteoclast-induced bone resorption

Authors: Jin-Gang Yang, Bao Sun, Zheng Wang, Xing Li, Jia-Hui Gao, Jia-Jun Qian, Jiang Li, Wen-Jia Wei, Ping Zhang, Wei Wang