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Engineered immunogens to elicit antibodies against conserved coronavirus epitopes

Authors: A Brenda Kapingidza, Daniel J Marston, Caitlin Harris, Daniel Wrapp, Kaitlyn Winters, Dieter Mielke, Lu Xiaozhi, Qi Yin, Andrew Foulger, Rob Parks, Maggie Barr, Amanda Newman, Alexandra Schäfer, Amanda Eaton, Justine Mae Flores, Austin Harner, Nicholas J Catanzaro, Michael L Mallory, Melissa D Mattocks, Christopher Beverly, Brianna Rhodes, Katayoun Mansouri, Elizabeth Van Itallie, Pranay Vure, Brooke Dunn, Taylor Keyes, Sherry Stanfield-Oakley, Christopher W Woods, Elizabeth A Petzold, Emmanuel B Walter, Kevin Wiehe, Robert J Edwards, David C Montefiori, Guido Ferrari, Ralph Baric, Derek W Cain, Kevin O Saunders, Barton F Haynes, Mihai L Azoitei

Journal: Nat Commun

PubMed ID: 38036525

Doi: 10.1038/s41467-023-43638-9

Products & Services: Protein and Antibody Isolation

Engineered IL-7 synergizes with IL-12 immunotherapy to prevent T cell exhaustion and promote memory without exacerbating toxicity

Authors: Seounghun Kang, Aslan Mansurov, Trevin Kurtanich, Hye Rin Chun, Anna J Slezak, Lisa R Volpatti, Kevin Chang, Thomas Wang, Aaron T Alpar, Kirsten C Refvik, O Isabella Hansen, Gustavo J Borjas, Ha-Na Shim, Kevin T Hultgren, Suzana Gomes, Ani Solanki, Jun Ishihara, Melody A Swartz, Jeffrey A Hubbell

Journal: Sci Adv

PubMed ID: 38019919

Doi: 10.1126/sciadv.adh9879

Products & Services: Protein and Antibody Isolation

Role and mechanism of miR-871-3p/Megf8 in regulating formaldehyde-induced cardiomyocyte inflammation and congenital heart disease

Authors: Xiaoli Yuan, Rui Chen, Gang Luo, Pin Sun, Xiaoxia Song, Jianmin Ma, Ruicong Sun, Tao Yu, Zhirong Jiang

Journal: Int Immunopharmacol

PubMed ID: 38039718

Doi: 10.1016/j.intimp.2023.111297

Products & Services: Protein and Antibody Isolation

Exosome-targeted delivery of METTL14 regulates NFATc1 m6A methylation levels to correct osteoclast-induced bone resorption

Authors: Jin-Gang Yang, Bao Sun, Zheng Wang, Xing Li, Jia-Hui Gao, Jia-Jun Qian, Jiang Li, Wen-Jia Wei, Ping Zhang, Wei Wang

Journal: Cell Death Dis

PubMed ID: 37957146

Doi: 10.1038/s41419-023-06263-4

Products & Services: Protein Electrophoresis and Western

RAGE Is a Receptor for SARS-CoV-2 N Protein and Mediates N Protein-induced Acute Lung Injury

Authors: Jie Xia, Jiangmei Wang, Liyang Ying, Ruoqiong Huang, Kai Zhang, Ruoyang Zhang, Wenqi Tang, Qi Xu, Dengming Lai, Yan Zhang, Yaoqin Hu, Xiaodie Zhang, Ruoxi Zang, Jiajie Fan, Qiang Shu, Jianguo Xu

Journal: Am J Respir Cell Mol Biol

PubMed ID: 37478333

Doi: 10.1165/rcmb.2022-0351OC

Products & Services: Recombinant Proteins

Plant carbonic anhydrase-like enzymes in neuroactive alkaloid biosynthesis

Authors: Ryan S Nett, Yaereen Dho, Chun Tsai, Daria Passow, Jaime Martinez Grundman, Yun-Yee Low, Elizabeth S Sattely

Journal: Nature

PubMed ID: 37938780

Doi: 10.1038/s41586-023-06716-y

Products & Services: Protein and Antibody Isolation

Conserved antigen structures and antibody-driven variations on foot-and-mouth disease virus serotype A revealed by bovine neutralizing monoclonal antibodies

Authors: Kun Li, Yong He, Li Wang, Pinghua Li, Huifang Bao, Shulun Huang, Shasha Zhou, Guoqiang Zhu, Yali Song, Ying Li, Sheng Wang, Qianliang Zhang, Pu Sun, Xingwen Bai, Zhixun Zhao, Zhiyong Lou, Yimei Cao, Zengjun Lu, Zaixin Liu

Journal: PLoS Pathog

PubMed ID: 37983290

Doi: 10.1371/journal.ppat.1011811

Products & Services: Protein and Antibody Isolation

BRD4354 is a Potent Covalent Inhibitor against the SARS-CoV-2 Main Protease

Authors: Yan J. Sheng; Syuan-Ting Alex Kuo; Tingyuan Yang; David H. Russell; Xin Yan; Shiqing Xu; Wenshe R. Liu; Carol A. Fierke

Journal: Biochemistry

PubMed ID: 38329238

Doi: 10.1021/acs.biochem.3c00685

Products & Services: Protein and Antibody Isolation

Novel and unique rheumatoid factors cross-react with viral epitopes in COVID-19

Authors: Maya F Amjadi, Maxwell H Parker, Ryan R Adyniec, Zihao Zheng, Alex M Robbins, S Janna Bashar, Michael F Denny, Sara S McCoy, Irene M Ong, Miriam A Shelef

Journal: J Autoimmun

PubMed ID: 37956528

Doi: 10.1016/j.jaut.2023.103132

Products & Services: Protein and Antibody Isolation

Diurnal regulation of alternative splicing associated with thermotolerance in rice by two glycine-rich RNA-binding proteins

Authors: Chuang Yang, Anni Luo, Hai-Ping Lu, Seth Jon Davis, Jian-Xiang Liu

Journal: Sci Bull (Beijing)

PubMed ID: 38044192

Doi: 10.1016/j.scib.2023.11.046

Products & Services: Protein and Antibody Isolation