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Short N-terminal disordered regions and the proline-rich domain are major regulators of phase transitions for full-length UBQLN1, UBQLN2 and UBQLN4

Authors: Thuy P Dao, Anitha Rajendran, Sarasi K K Galagedera, William Haws, Carlos A Castañeda

Journal: biorxiv

PubMed ID: 37808720

Doi: 10.1101/2023.09.27.559790

Products & Services: Protein and Antibody Isolation

Enhancing CAR T-cell Therapy Using Fab-Based Constitutively Heterodimeric Cytokine Receptors

Authors: Matteo Righi, Isaac Gannon, Matthew Robson, Saket Srivastava, Evangelia Kokalaki, Thomas Grothier, Francesco Nannini, Christopher Allen, Yuchen V Bai, James Sillibourne, Shaun Cordoba, Simon Thomas, Martin Pule

Journal: Cancer Immunol Res

PubMed ID: 37352396

Doi: 10.1158/2326-6066.CIR-22-0640

Products & Services: Protein and Antibody Isolation

Ultrasound-Induced Microbubble Cavitation for Targeted Delivery of MiR-29b Mimic to Treat Cardiac Fibrosis

Authors: Rafey A Feroze, Jonathan Kopechek, Jianhui Zhu, Xucai Chen, Flordeliza S Villanueva

Journal: Ultrasound Med Biol

PubMed ID: 37749011

Doi: 10.1016/j.ultrasmedbio.2023.08.025

Products & Services: Protein and Antibody Isolation

Glycoengineering directs de novo biomanufacturing of UPEC O21 O-antigen polysaccharide based glycoprotein

Authors: Yuhui Wang , Andrei V Perepelov , Sof'ya N Senchenkova , Gege Lu , Xiaohan Wang , Guozhen Ma , Qian Yang , Jian Yuan , Yanling Wang , Lijie Xie , Xiaolong Jiang , Jingliang Qin , Dan Liu , Miaomiao Liu , Di Huang , Bin Liu

Journal: Int J Biol Macromol .

PubMed ID: 37739281

Doi: 10.1016/j.ijbiomac.2023.126993

Products & Services: Protein Electrophoresis and Western

Mechanistic insights into nucleosomal H2B monoubiquitylation mediated by yeast Bre1-Rad6 and its human homolog RNF20/RNF40-hRAD6A

Authors: Zhiheng Deng, Huasong Ai, Maoshen Sun, Zebin Tong, Yunxiang Du, Qian Qu, Liying Zhang, Ziyu Xu, Shixian Tao, Qiang Shi, Jia-Bin Li, Man Pan, Lei Liu

Journal: Mol Cell

PubMed ID: 37633270

Doi: 10.1016/j.molcel.2023.08.001

Products & Services: Protein and Antibody Isolation

Cryo-EM structures of human organic anion transporting polypeptide OATP1B1

Authors: Ziyang Shan, Xuemei Yang, Huihui Liu, Yafei Yuan, Yuan Xiao, Jing Nan, Wei Zhang, Wenqi Song, Jufang Wang, Feiwen Wei, Yanqing Zhang

Journal: Cell Res

PubMed ID: 37674011

Doi: 10.1038/s41422-023-00870-8

Products & Services: Protein and Antibody Isolation

DSCC1 interacts with HSP90AB1 and promotes the progression of lung adenocarcinoma via regulating ER stress

Authors: Xu Lin, Ye-Han Liu, Huan-Qi Zhang, Lin-Wen Wu, Qi Li, Jun Deng, Qingyi Zhang, Yuhong Yang, Chong Zhang, Yang-Ling Li, Jian Hu

Journal: Cancer Cell Int

PubMed ID: 37742009

Doi: 10.1186/s12935-023-03047-w

Products & Services: Protein and Antibody Isolation

Phosphatidylinositol-specific phospholipase C can decrease Müller cell viability and suppress its phagocytic activity by modulating PI3K/AKT signaling pathway

Authors: Bianjin Sun, Shudan Lin, Mengmeng Zheng, Beijia Zheng, Liping Mao, Yunfeng Gu, Jiabei Cai, Yiran Dai, Meiqin Zheng, Yongliang Lou

Journal: Can J Microbiol

PubMed ID: 37672795

Doi: 10.1139/cjm-2023-0044

Products & Services: Protein and Antibody Isolation

Omicron variant neutralizing antibodies following BNT162b2 BA4/5 versus mRNA-1273 BA1 bivalent vaccination in patients with end-stage kidney disease

Authors: Kevin Yau, Alexandra Kurtesi, Freda Qi, Melanie Delgado-Brand, Tulunay R Tursun, Queenie Hu, Miten Dhruve, Christopher Kandel, Omosomi Enilama, Adeera Levin, Yidi Jiang, W Rod Hardy, Darren A Yuen, Jeffrey Perl, Christopher T Chan, Jerome A Leis, Matthew J Oliver, Karen Colwill, Anne-Claude Gingras, Michelle A Hladunewich

Journal: Nat Commun

PubMed ID: 37758707

Doi: 10.1038/s41467-023-41678-9

Products & Services: Protein and Antibody Isolation

AXL Inhibition Improves the Antitumor Activity of Chimeric Antigen Receptor T Cells

Authors: R Leo Sakemura, Mehrdad Hefazi, Michelle J Cox, Elizabeth L Siegler, Sutapa Sinha, Michael J Hansen, Carli M Stewart, Jennifer M Feigin, Claudia Manriquez Roman, Kendall J Schick, Ismail Can, Erin E Tapper, Paulina Horvei, Mohamad M Adada, Evandro D Bezerra, Lionel Aurelien Kankeu Fonkoua, Michael W Ruff, Cynthia L Forsman, Wendy K Nevala, Justin C Boysen, Renee C Tschumper, Cory L Grand, Kameswara R Kuchimanchi, Lars Mouritsen, Jason M Foulks, Steven L Warner, Timothy G Call, Sameer A Parikh, Wei Ding, Neil E Kay, Saad S Kenderian

Journal: Cancer Immunol Res

PubMed ID: 37378662

Doi: 10.1158/2326-6066.CIR-22-0254

Products & Services: Protein and Antibody Isolation