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Molecular basis of methyl-salicylate-mediated plant airborne defence

Authors: Qian Gong , Yunjing Wang , Linfang He , Fan Huang , Danfeng Zhang , Yan Wang , Xiang Wei , Meng Han , Haiteng Deng , Lan Luo , Feng Cui , Yiguo Hong, Yule Liu

Journal: Nature .

PubMed ID: 37704724

Doi: 10.1038/s41586-023-06533-3

Products & Services: Protein and Antibody Isolation

Preclinical efficacy of a cell division protein candidate gonococcal vaccine identified by artificial intelligence

Authors: Sunita Gulati, Andreas Holm Mattsson, Sophie Schussek, Bo Zheng, Rosane B DeOliveira, Jutamas Shaughnessy, Lisa A Lewis, Peter A Rice, Pär Comstedt, Sanjay Ram

Journal: MBio

PubMed ID: 37905891

Doi: 10.1128/mbio.02500-23

Products & Services: Protein and Antibody Isolation

Biochemical and biophysical properties of a rare TTRA81V mutation causing mild transthyretin amyloid cardiomyopathy

Authors: Qiuyan Sha, Yanli Zhang, Mengdie Wang, Jialu Sun, Yunlong Zhang, Xinxin Zhang, Ning Wang, Yu Liu, Ying Liu

Journal: ESC Heart Fail

PubMed ID: 37827496

Doi: 10.1002/ehf2.14543

Products & Services: Protein and Antibody Isolation

Condensation of the N-terminal domain of human topoisomerase 1 is driven by electrostatic interactions and tuned by its charge distribution

Authors: Greta Bianchi, Marco Mangiagalli, Diletta Ami, Junaid Ahmed, Silvia Lombardi, Sonia Longhi, Antonino Natalello, Peter Tompa, Stefania Brocca

Journal: Int J Biol Macromol

PubMed ID: 38287572

Doi: 10.1016/j.ijbiomac.2023.127754

Products & Services: Protein and Antibody Isolation

Rapamycin nanoparticles increase the therapeutic window of engineered interleukin-2 and drive expansion of antigen-specific regulatory T cells for protection against autoimmune disease

Authors: Takashi Kei Kishimoto, Max Fournier, Alicia Michaud, Gina Rizzo, Christopher Roy, Teresa Capela, Natasha Nukolova, Ning Li, Liam Doyle, Fen-Ni Fu, Derek VanDyke, Peter G Traber, Jamie B Spangler, Sheldon S Leung, Petr O Ilyinskii

Journal: J Autoimmun

PubMed ID: 37844543

Doi: 10.1016/j.jaut.2023.103125

Products & Services: Protein and Antibody Isolation

Industry updates from the field of stem cell research and regenerative medicine in August 2023

Authors: Dusko Ilic, Mirjana Liovic

Journal: Regen Med

PubMed ID: 37786963

Doi: 10.2217/rme-2023-0181

Products & Services: Protein and Antibody Isolation

A newly identified ferritin L-subunit variant results in increased proteasomal subunit degradation, impaired complex assembly, and severe hypoferritinemia

Authors: Dayana Shagidov, Noga Guttmann-Raviv, Séverine Cunat, Liora Frech, Muriel Giansily-Blaizot, Niraj Ghatpande, Gili Abelya, Gabriel A Frank, Patricia Aguilar Martinez, Esther G Meyron-Holtz

Journal: Am J Hematol

PubMed ID: 37867341

Doi: 10.1002/ajh.27124

Products & Services: Protein and Antibody Isolation

Genistein alleviates chronic heat stress-induced lipid metabolism disorder and mitochondrial energetic dysfunction by activating the GPR30-AMPK-PGC-1α signaling pathways in the livers of broiler chickens

Authors: Longlong Li, Ze Lu, Yulei Wang, Ying Yang, Huihui Wang, Haitian Ma

Journal: Poult Sci

PubMed ID: 37984004

Doi: 10.1016/j.psj.2023.103251

Products & Services: Protein and Antibody Isolation

Intervention of AXL in EGFR Signaling via Phosphorylation and Stabilization of MIG6 in Non-Small Cell Lung Cancer

Authors: Ya-Yu Yang, Sheng-Chieh Lin, Jong-Ding Lay, Chun-Yu Cho, Te-Hsuan Jang, Hsiu-Ying Ku, Chih-Jung Yao, Shuang-En Chuang

Journal: Int J Mol Sci

PubMed ID: 37834326

Doi: 10.3390/ijms241914879

Products & Services: Protein and Antibody Isolation

Unfolding of an RNA G-quadruplex motif in the negative strand genome of porcine reproductive and respiratory syndrome virus by host and viral helicases to promote viral replication

Authors: Puxian Fang, Congbao Xie, Ting Pan, Ting Cheng, Wei Chen, Sijin Xia, Tong Ding, Junkang Fang, Yanrong Zhou, Liurong Fang, Dengguo Wei, Shaobo Xiao

Journal: Nucleic Acids Res

PubMed ID: 37739415

Doi: 10.1093/nar/gkad759

Products & Services: Protein and Antibody Isolation