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Structural Insights into the Unexpected Agonism of Tetracyclic Antidepressants at Serotonin Receptors 5-HT1eR and 5-HT1FR

Authors: Gregory Zilberg, Alexandra K Parpounas, Audrey L Warren, Bianca Fiorillo, Davide Provasi, Marta Filizola, Daniel Wacker

Journal: SCIENCE ADVANCES

PubMed ID: 37986777

Doi: 10.1101/2023.10.05.561100

Products & Services: Protein and Antibody Isolation

Functionalizing Yeast Lipid Droplets as Versatile Biomaterials

Authors: Ankita Suri, Kevin K Y Hu, Tayyaba Younas, Geoff Dumsday, Victoria S Haritos

Journal: Small

PubMed ID: 38566530

Doi: 10.1002/smll.202308463

Products & Services: Protein Electrophoresis and Western

Broadly neutralizing antibodies against emerging delta-coronaviruses

Authors: Megi Rexhepaj, Young-Jun Park, Lisa Perruzza, Daniel Asarnow, Mathew Mccallum, Katja Culap, Christian Saliba, Giada Leoni, Alessio Balmelli, Courtney N Yoshiyama, Miles S Dickinson, Joel Quispe, Jack Taylor Brown, M Alejandra Tortorici, Kaitlin R Sprouse, Ashley L Taylor, Tyler N Starr, Davide Corti, Fabio Benigni, David Veesler

Journal: biorxiv

PubMed ID: 38617231

Doi: 10.1101/2024.03.27.586411

Products & Services: Protein and Antibody Isolation

Pharmacology of PACAP and VIP receptors in the spinal cord highlights the importance of the PAC receptor

Authors: Zoe Tasma, Tayla A Rees, Song Guo, Sheryl Tan, Simon J O'Carroll, Richard L M Faull, Maurice A Curtis, Sarah L Christensen, Debbie L Hay, Christopher S Walker

Journal: Br J Pharmacol

PubMed ID: 38616050

Doi: 10.1111/bph.16376

Products & Services: Protein and Antibody Isolation

Probing altered receptor specificities of antigenically drifting human H3N2 viruses by chemoenzymatic synthesis, NMR, and modeling

Authors: Luca Unione, Augustinus N A Ammerlaan, Gerlof P Bosman, Elif Uslu, Ruonan Liang, Frederik Broszeit, Roosmarijn van der Woude, Yanyan Liu, Shengzhou Ma, Lin Liu, Marcos Gómez-Redondo, Iris A Bermejo, Pablo Valverde, Tammo Diercks, Ana Ardá, Robert P de Vries, Geert-Jan Boons

Journal: Nat Commun

PubMed ID: 38582892

Doi: 10.1038/s41467-024-47344-y

Products & Services: Protein and Antibody Isolation

Co-delivery of Cas9 mRNA and guide RNAs for editing of LGMN gene represses breast cancer cell metastasis

Authors: Yue Wang, Yatu Peng, Guanghui Zi, Jin Chen, Baowei Peng

Journal: Sci Rep

PubMed ID: 38582932

Doi: 10.1038/s41598-024-58765-6

Products & Services: Protein and Antibody Isolation

CoCas9 is a compact nuclease from the human microbiome for efficient and precise genome editing

Authors: Eleonora Pedrazzoli, Michele Demozzi, Elisabetta Visentin, Matteo Ciciani, Ilaria Bonuzzi, Laura Pezzè, Lorenzo Lucchetta, Giulia Maule, Simone Amistadi, Federica Esposito, Mariangela Lupo, Annarita Miccio, Alberto Auricchio, Antonio Casini, Nicola Segata, Anna Cereseto

Journal: Nat Commun

PubMed ID: 38658578

Doi: 10.1038/s41467-024-47800-9

Products & Services: CRISPR RNAs/Cas9 Proteins(INACTIVE)

Decoding the blueprint of receptor binding by filoviruses through large-scale binding assays and machine learning

Authors: Gorka Lasso; Michael Grodus; Estefania Valencia; Veronica DeJesus; Eliza Liang; Isabel Delwel; Rob H. Bortz; Dmitry Lupyan; Hanna Y. Ehrlich; Adrian A. Castellanos; Andrea Gazzo; Heather L. Wells; Supaporn Wacharapluesadee; Alexandre Tremeau-Bravard; Janine F.R. Seetahal; Tom Hughes; Jimmy Lee; Mei-Ho Lee; Anna R. Sjodin; Marike Geldenhuys; Marinda Mortlock; Isamara Navarrete-Macias; Kirsten Gilardi; Michael R. Willig; Alessandra F.D. Nava; Elisabeth H. Loh; Makda Asrat; Tierra Smiley-Evans; Walter S. Magesa; Sijali Zikankuba; David Wolking; Gerardo Suz n; Rafael Ojeda-Flores; Christine V.F. Carrington; Ariful Islam; Jonathan H. Epstein; Wanda Markotter; Christine K. Johnson; Tracey Goldstein; Barbara A. Han; Jonna A.K. Mazet; Rohit K. Jangra; Kartik Chandran; Simon J. Anthony

Journal: Cell Host & Microbe

PubMed ID: 39818205

Doi: 10.1016/j.chom.2024.12.016

Products & Services: Protein and Antibody Isolation

Structural insights into human EMC and its interaction with VDAC

Authors: Mingyue Li, Chunli Zhang, Yuntao Xu, Shaobai Li, Chenhui Huang, Jian Wu, Ming Lei

Journal: Aging (Albany NY)

PubMed ID: 38517390

Doi: 10.18632/aging.205660

Products & Services: Protein and Antibody Isolation

A Novel Polymer Nanoparticle Polydimethyl Diallyl Ammonium Chloride as An Adjuvant Enhances the Immune Response of SARS-CoV-2 Subunit Vaccine

Authors: Lili Ren, Chengcheng Ouyang, Shuqing Zhao, Qiqi Zheng, Weilu Guo, Baochao Fan, Jinzhu Zhou, Wei Zhang, Mi Hu, Jizong Li, Bin Li