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Engineered immunogens to elicit antibodies against conserved coronavirus epitopes
Authors: A Brenda Kapingidza, Daniel J Marston, Caitlin Harris, Daniel Wrapp, Kaitlyn Winters, Dieter Mielke, Lu Xiaozhi, Qi Yin, Andrew Foulger, Rob Parks, Maggie Barr, Amanda Newman, Alexandra Schäfer, Amanda Eaton, Justine Mae Flores, Austin Harner, Nicholas J Catanzaro, Michael L Mallory, Melissa D Mattocks, Christopher Beverly, Brianna Rhodes, Katayoun Mansouri, Elizabeth Van Itallie, Pranay Vure, Brooke Dunn, Taylor Keyes, Sherry Stanfield-Oakley, Christopher W Woods, Elizabeth A Petzold, Emmanuel B Walter, Kevin Wiehe, Robert J Edwards, David C Montefiori, Guido Ferrari, Ralph Baric, Derek W Cain, Kevin O Saunders, Barton F Haynes, Mihai L Azoitei
Journal: Nat Commun
PubMed ID: 38036525
Doi: 10.1038/s41467-023-43638-9
Engineered IL-7 synergizes with IL-12 immunotherapy to prevent T cell exhaustion and promote memory without exacerbating toxicity
Authors: Seounghun Kang, Aslan Mansurov, Trevin Kurtanich, Hye Rin Chun, Anna J Slezak, Lisa R Volpatti, Kevin Chang, Thomas Wang, Aaron T Alpar, Kirsten C Refvik, O Isabella Hansen, Gustavo J Borjas, Ha-Na Shim, Kevin T Hultgren, Suzana Gomes, Ani Solanki, Jun Ishihara, Melody A Swartz, Jeffrey A Hubbell
Journal: Sci Adv
PubMed ID: 38019919
Doi: 10.1126/sciadv.adh9879
Exosome-targeted delivery of METTL14 regulates NFATc1 m6A methylation levels to correct osteoclast-induced bone resorption
Authors: Jin-Gang Yang, Bao Sun, Zheng Wang, Xing Li, Jia-Hui Gao, Jia-Jun Qian, Jiang Li, Wen-Jia Wei, Ping Zhang, Wei Wang
Journal: Cell Death Dis
PubMed ID: 37957146
Doi: 10.1038/s41419-023-06263-4
Interactions of Histone Deacetylase 6 with DNA Damage Repair Factors Strengthen its Utility as a Combination Drug Target in High-Grade Serous Ovarian Cancer
Authors: Jolene M Duda, Stefani N Thomas
Journal: ACS Pharmacol Transl Sci
PubMed ID: 38107255
Doi: 10.1021/acsptsci.3c00215
RAGE Is a Receptor for SARS-CoV-2 N Protein and Mediates N Protein-induced Acute Lung Injury
Authors: Jie Xia, Jiangmei Wang, Liyang Ying, Ruoqiong Huang, Kai Zhang, Ruoyang Zhang, Wenqi Tang, Qi Xu, Dengming Lai, Yan Zhang, Yaoqin Hu, Xiaodie Zhang, Ruoxi Zang, Jiajie Fan, Qiang Shu, Jianguo Xu
Journal: Am J Respir Cell Mol Biol
PubMed ID: 37478333
Doi: 10.1165/rcmb.2022-0351OC
Products & Services: Recombinant Proteins   
Development of an Electrochemical, Aptamer-Based Sensor for Dynamic Detection of Neuropeptide Y
Authors: Jordan M Seibold, Sanduni W Abeykoon, Ashley E Ross, Ryan J White
Journal: ACS Sens
PubMed ID: 38033269
Doi: 10.1021/acssensors.3c00855
Products & Services: Recombinant Proteins   
Environment relevant exposure of perfluorooctanoic acid accelerates the growth of hepatocellular carcinoma cells through mammalian target of rapamycin (mTOR) signal pathway
Authors: Jiawei Hong, Xiaoyan Wang, Hangbiao Jin, Yuanchen Chen, Yifan Jiang, Keyi Du, Diyu Chen, Shusen Zheng, Linping Cao
Journal: Environ Pollut
PubMed ID: 37967710
Doi: 10.1016/j.envpol.2023.122910
Molecular basis for the catalytic mechanism of human neutral sphingomyelinases 1 (hSMPD2)
Authors: Jingbo Yi, Boya Qi, Jian Yin, Ruochong Li, Xudong Chen, Junhan Hu, Guohui Li, Sensen Zhang, Yuebin Zhang, Maojun Yang
Journal: Nat Commun
PubMed ID: 38012235
Doi: 10.1038/s41467-023-43580-w
Extracellular and intracellular destruction of Pseudomonas aeruginosa by Dictyostelium discoideum phagocytes mobilize different antibacterial mechanisms
Authors: Imen Ayadi, Otmane Lamrabet, Raphael Munoz-Ruiz, Tania Jauslin, Cyril Guilhen, Pierre Cosson
Journal: Mol Microbiol
PubMed ID: 38017607
Doi: 10.1111/mmi.15197
Critical role of TPRN rings in the stereocilia for hearing
Authors: Jieyu Qi, Fangzhi Tan, Liyan Zhang, Yinyi Zhou, Ziyu Zhang, Qiuhan Sun, Nianci Li, Yuan Fang, Xin Chen, Yunhao Wu, Guisheng Zhong, Renjie Chai
Journal: Mol Ther
PubMed ID: 37952086
Doi: 10.1016/j.ymthe.2023.11.011

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