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CDKN2A/B homozygous deletion sensitizes IDH-mutant glioma to CDK4/6 inhibition

Authors: Ali M Nasser, Lisa Melamed, Ethan Wetzel, Chia-Chen Chang, Hiroaki Nagashima, Yosuke Kitagawa, Logan Muzyka, Hiroaki Wakimoto, Daniel P Cahill, Julie J Miller

Journal: Clin Cancer Res

PubMed ID: 38718141

Doi: 10.1158/1078-0432.CCR-24-0562

Products & Services: Protein and Antibody Isolation

HAP40 modulates mutant Huntingtin aggregation and toxicity in Huntington's disease mice

Authors: Laiqiang Chen, Yiyang Qin, Tingting Guo, Wenzhen Zhu, Jingpan Lin, Tingting Xing, Xuezhi Duan, Yiran Zhang, Eshu Ruan, Xiang Li, Peng Yin, Shihua Li, Xiao-Jiang Li, Su Yang

Journal: Cell Death Dis

PubMed ID: 38744826

Doi: 10.1038/s41419-024-06716-4

Products & Services: Protein Electrophoresis and Western

AAV-mediated Gene Cocktails Enhance Supporting Cell Reprogramming and Hair Cell Regeneration

Authors: Liyan Zhang, Xin Chen, Xinlin Wang, Yinyi Zhou, Yuan Fang, Xingliang Gu, Ziyu Zhang, Qiuhan Sun, Nianci Li, Lei Xu, Fangzhi Tan, Renjie Chai, Jieyu Qi

Journal: Adv Sci (Weinh)

PubMed ID: 38810137

Doi: 10.1002/advs.202304551

Products & Services: Protein and Antibody Isolation

A 3D spheroid model of quadruple cell co-culture with improved liver functions for hepatotoxicity prediction

Authors: Baiyang Sun, Zihe Liang, Yupeng Wang, Yue Yu, Xiaobing Zhou, Xingchao Geng, Bo Li

Journal: Toxicology

PubMed ID: 38740170

Doi: 10.1016/j.tox.2024.153829

Products & Services: Protein and Antibody Isolation

CaptureSelect FcXP affinity medium exhibits strong aggregate separation capability

Authors: Wanyuan Dong, Dan Zhang, Yifeng Li

Journal: Protein Expr Purif

PubMed ID: 38759705

Doi: 10.1016/j.pep.2024.106503

Products & Services: Protein Electrophoresis and Western

Variation in structural motifs within SARS-related coronavirus spike proteins

Authors: Francesca R Hills, Alice-Roza Eruera, James Hodgkinson-Bean, Fátima Jorge, Richard Easingwood, Simon H J Brown, James C Bouwer, Yi-Ping Li, Laura N Burga, Mihnea Bostina

Journal: PLoS Pathog

PubMed ID: 38805567

Doi: 10.1371/journal.ppat.1012158

Products & Services: Protein and Antibody Isolation

Structure of the lens MP20 mediated adhesive junction

Authors: William J Nicolas, Anna Shiriaeva, Michael W Martynowycz, Angus C Grey, Yasmeen Ruma, Paul J Donaldson, Tamir Gonen

Journal: biorxiv

PubMed ID: 38798449

Doi: 10.1101/2024.05.13.594022

Products & Services: Protein and Antibody Isolation

Structural pharmacology and therapeutic potential of 5-methoxytryptamines

Authors: Audrey L Warren, David Lankri, Michael J Cunningham, Inis C Serrano, Lyonna F Parise, Andrew C Kruegel, Priscilla Duggan, Gregory Zilberg, Michael J Capper, Vaclav Havel, Scott J Russo, Dalibor Sames, Daniel Wacker

Journal: Nature

PubMed ID: 38720072

Doi: 10.1038/s41586-024-07403-2

Products & Services: Protein and Antibody Isolation

Proteomic and lipidomic landscape of the infrapatellar fat pad and its clinical significance in knee osteoarthritis

Authors: Bizhi Tu, Zheng Zhu, Peizhi Lu, Run Fang, Cheng Peng, Jun Tong, Rende Ning

Journal: Biochim Biophys Acta Mol Cell Biol Lipids

PubMed ID: 38788831

Doi: 10.1016/j.bbalip.2024.159513

Products & Services: Protein and Antibody Isolation

Biochemical characterization of a novel thermostable ulvan lyase from Tamlana fucoidanivorans CW2-9

Authors: Yan Xu, Jin Li, Lu An, Yuankai Qiu, Aihua Mao, Zhixiao He, Jialing Guo, Hanbing Yan, Han Li, Zhong Hu