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Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutations.

Authors: BirkinshawRichard W，GongJia-Nan，LuoCindy S，LioDaisy，WhiteChristine A，AndersonMary Ann，BlomberyPiers，LesseneGuillaume，MajewskiIan J，ThijssenRachel，RobertsAndrew W，HuangDavid C S，ColmanPeter M，CzabotarPet

Journal: Nat Commun

PubMed ID: 31160589

Doi: 10.1038/s41467-019-10363-1

Products & Services: Protein and Antibody Isolation

Cellular response upon proliferation in the presence of an active mitotic checkpoint.

Authors: CornoAndrea，ChiroliElena，GrossFridolin，VernieriClaudio，MataforaVittoria，MaffiniStefano，Cosentino LagomarsinoMarco，BachiAngela，CilibertoAn

Journal: Life Sci Alliance

PubMed ID: 31068378

Doi: 10.26508/lsa.201900380

Products & Services: Recombinant Proteins

Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis.

Authors: HuangMiller，TailorJignesh，ZhenQiqi，GillmorAaron H，MillerMatthew L，WeishauptHolger，ChenJustin，ZhengTina，NashEmily K，McHenryLauren K，AnZhenyi，YeFubaiyang，TakashimaYasuhiro，ClarkeJames，AyeteyHarold，CavalliFlorence M G，LuuBetty，MoriarityBranden S，IlkhanizadehShirin，ChavezLukas，YuChunying，KurianKathreena M，MagnaldoThierry，SevenetNicolas，KochPhilipp，PollardSteven M，DirksPeter，SnyderMichael P，LargaespadaDavid A，ChoYoon Jae，PhillipsJoanna J，SwartlingFredrik J，MorrissyA Sorana，KoolMarcel，PfisterStefan M，TaylorMichael D，SmithAustin，WeissWilli

Journal: Cell Stem Cell

PubMed ID: 31204176

Doi: 10.1016/j.stem.2019.05.013

Products & Services: Recombinant Proteins

Discovery of potent necroptosis inhibitors targeting RIPK1 kinase activity for the treatment of inflammatory disorder and cancer metastasis.

Authors: HouJue，JuJie，ZhangZili，ZhaoCong，LiZhanhui，ZhengJiyue，ShengTian，ZhangHongjian，HuLinkun，YuXiaoliang，ZhangWei，LiYangxin，WuMeng，MaHaikuo，ZhangXiaohu，HeS

Journal: Cell Death Dis

PubMed ID: 31235688

Doi: 10.1038/s41419-019-1735-6

Products & Services: Recombinant Proteins

Polycystin-1 affects cancer cell behaviour and interacts with mTOR and Jak signalling pathways in cancer cell lines.

Authors: PapavassiliouKostas A，ZoiIlianna，GargalionisAntonios N，KoutsilierisMic

Journal: J. Cell. Mol. Med.

PubMed ID: 31251475

Doi: 10.1111/jcmm.14506

Products & Services: Recombinant Proteins

Structural insights into the functional mechanism of the ubiquitin ligase E6AP

Authors: Zhen Wang; Fengying Fan; Zhihai Li; Fei Ye; Qingxia Wang; Rongchao Gao; Jiaxuan Qiu; Yixin Lv; Min Lin; Wenwen Xu; Cheng Luo; Xuekui Yu

Journal: Nature Communications

PubMed ID: 38670961

Doi: 10.1038/s41467-024-47586-w

Products & Services: Protein and Antibody Isolation

RAD18 may function as a predictor of response to preoperative concurrent chemoradiotherapy in patients with locally advanced rectal cancer through caspase-9-caspase-3-dependent apoptotic pathway.

Authors: Yan X, Chen J, Meng Y, He C, Zou S, Li P, Chen M, Wu J, Ding WQ, Zhou J

Journal: Cancer Med.

PubMed ID: 31033216

Doi: 10.1002/cam4.2203

Products & Services: Protein Electrophoresis and Western

Vascular endothelial growth factor-loaded elastin-hydrogel modification of the pericardium improves endothelialization potential of bioprosthetic heart valves.

Authors: LeiLang，TaoXin，XieLifeng，HongZheng

Journal: J Biomater Appl

PubMed ID: 31195917

Doi: 10.1177/0885328219854336

Products & Services: Recombinant Proteins

Characterization of blood-brain barrier integrity in a B-cell-dependent mouse model of multiple sclerosis.

Authors: BellLuisa，KoenigerTobias，TackeSabine，KuertenStef

Journal: Histochem Cell Biol

PubMed ID: 30666403

Doi: 10.1007/s00418-019-01768-6

Products & Services: Recombinant Proteins

Magnesium protects against sepsis by blocking gasdermin D N-terminal-induced pyroptosis.

Authors: WangDingyu，ZhengJiashuo，HuQiongyuan，ZhaoCheng，ChenQianyue，ShiPeiliang，ChenQin，ZouYujie，ZouDayuan，LiuQiyao，PeiJingwen，WuXiuwen，GaoXiang，RenJianan，LinZh

Journal: Cell Death Differ.

PubMed ID: 31209359

Doi: 10.1038/s41418-019-0366-x

Products & Services: Protein and Antibody Isolation