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Reversible ubiquitination conferred by domain shuffling controls paired NLR immune receptor complex homeostasis in plant immunity

Authors: Zhiyi Chen, Jianhua Huang, Jianyu Li, Frank L. H. Menke, Jonathan D. G. Jones & Hailong Guo

Journal: Nature Communications

Doi: 10.1038/s41467-025-57231-9

Products & Services: Protein and Antibody Isolation

Nucleotide-induced hyper-oligomerization inactivates transcription termination factor ρ

Authors: Bing Wang, Nelly Said, Tarek Hilal, Mark Finazzo, Markus C Wahl, Irina Artsimovitch

Journal: Nature Communications

PubMed ID: 39952913

Doi: 10.1038/s41467-025-56824-8

Products & Services: Protein Electrophoresis and Western

Structural basis of SIRT7 nucleosome engagement and substrate specificity

Authors: Carlos Moreno-Yruela, Babatunde E Ekundayo, Polina N Foteva, Dongchun Ni, Esther Calvino-Sanles, Henning Stahlberg, Beat Fierz

Journal: Nature Communications

PubMed ID: 39900593

Doi: 10.1038/s41467-025-56529-y

Products & Services: Protein Electrophoresis and Western

Cascaded immunotherapy with implantable dual-drug depots sequentially releasing STING agonists and apoptosis inducers

Authors: Kai Li, Xuan Yu, Yanteng Xu, Haixia Wang, Zheng Liu, Chong Wu, Xing Luo, Jiancheng Xu, Youqiang Fang, Enguo Ju, Shixian Lv, Hon Fai Chan, Yeh-Hsing Lao, Weiling He, Yu Tao, Mingqiang Li

Journal: Nature Communications

PubMed ID: 39952937

Doi: 10.1038/s41467-025-56407-7

Products & Services: Recombinant Proteins

Alternatively spliced NFKB1 transcripts enriched in Andean Aymara modulate inflammation, HIF and hemoglobin

Authors: Jihyun Song, Seonggyun Han, Ricardo Amaru, Lucie Lanikova, Teddy Quispe, Dongwook Kim, Jacob E Crawford, Soo Jin Kim, Younghee Lee, Josef T Prchal

Journal: Nature Communications

PubMed ID: 39971917

Doi: 10.1038/s41467-025-56848-0

Products & Services: Protein Electrophoresis and Western

Polyamine-Depleting Hydrogen-Bond Organic Frameworks Unleash Dendritic Cell and T Cell Vigor for Targeted CRISPR/Cas-Assisted Cancer Immunotherapy

Authors: Yongchun Pan, Fei Zeng, Xiaowei Luan, Guanzhong He, Shurong Qin, Qianglan Lu, Bangshun He, Xin Han, Yujun Song

Journal: Adv Mater

PubMed ID: 39972681

Doi: 10.1002/adma.202411886

Products & Services: Recombinant Proteins

A truncated pre-F protein mRNA vaccine elicits an enhanced immune response and protection against respiratory syncytial virus

Authors: Min Lin, Yifan Yin, Xiaomeng Zhao, Chen Wang, Xueqing Zhu, Letao Zhan, Li Chen, Siling Wang, Xue Lin, Jun Zhang, Ningshao Xia, Zizheng Zheng

Journal: Nat Commun

PubMed ID: 39910047

Doi: 10.1038/s41467-025-56302-1

Products & Services: Protein and Antibody Isolation

Perturbing Organelle-Level K+/Ca2+ Homeostasis by Nanotherapeutics for Enhancing Ion-Mediated Cancer Immunotherapy

Authors: Jun-Long Liang , Qian-Xiao Huang , Qi-Wen Chen , Xiao-Kang Jin , Zi-Yi Han 1, Ping Ji , Si-Xue Cheng , Wei-Hai Chen , Xian-Zheng Zhang

Journal: Adv Mater

PubMed ID: 39955648

Doi: 10.1002/adma.202416574

Products & Services: Recombinant Proteins

Beclin 1 prevents ISG15-mediated cytokine storms to secure fetal hematopoiesis and survival

Authors: Wen Wei, Xueqin Gao, Jiawei Qian, Lei Li, Chen Zhao, Li Xu, Yanfei Zhu, Zhenzhen Liu, Nengrong Liu, Xueqing Wang, Zhicong Jin, Bowen Liu, Lan Xu, Jin Dong, Suping Zhang, Jiarong Wang, Yumu Zhang, Yao Yu, Zhanjun Yan, Yanjun Yang, Jie Lu, Yixuan Fang, Na Yuan, Jianrong Wang

Journal: Journal of Clinical Investigation

PubMed ID: 39589832

Doi: 10.1172/JCI177375.

Products & Services: Protein and Antibody Isolation

Anti-Ebola virus mAb 3A6 protects highly viremic animals from fatal outcome via binding GP(1,2) in a position elevated from the virion membrane

Authors: Kathryn M Hastie, Zhe Li Salie, Zunlong Ke, Peter J Halfmann, Lisa Evans DeWald, Sara McArdle, Ariadna Grinyó, Edgar Davidson, Sharon L Schendel, Chitra Hariharan, Michael J Norris, Xiaoying Yu, Chakravarthy Chennareddy, Xiaoli Xiong, Megan Heinrich, Michael R Holbrook, Benjamin Doranz, Ian Crozier, Yoshihiro Kawaoka, Luis M Branco, Jens H Kuhn, John A G Briggs, Gabriella Worwa, Carl W Davis, Rafi Ahmed, Erica Ollmann Saphire

Journal: Nature Communications

PubMed ID: 39900911

Doi: 10.1038/s41467-025-56452-2

Products & Services: Protein and Antibody Isolation