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Anti-tumor activity of a novel proteasome inhibitor D395 against multiple myeloma and its lower cardiotoxicity compared with carfilzomib

Authors: Xuxing Shen, Chao Wu, Meng Lei, Qing Yan, Haoyang Zhang, Lina Zhang, Xueyuan Wang, Ye Yang, Jianyong Li, Yongqiang Zhu, Lijuan Chen

Journal: Cell Death Dis

PubMed ID: 33931582

Doi: 10.1038/s41419-021-03701-z

Products & Services: Recombinant Proteins

RNA-binding protein YBX1 promotes cell proliferation and invasiveness of nasopharyngeal carcinoma cells binding to AURKA mRNA

Authors: Yuanyuan Ban, Yixin Tan, Xiaoling Li, Xiayu Li, Zhaoyang Zeng, Wei Xiong, Guiyuan Li, Bo Xiang, Mei Yi

Journal: J Cancer

PubMed ID: 33976741

Doi: 10.7150/jca.56262

Products & Services: Recombinant Proteins

Diagnostic accuracy of three SARS-CoV2 antibody detection assays, neutralizing effect and longevity of serum antibodies

Authors: Marina Bubonja-Šonje, Lara Batičić, Maja Abram, Đurđica Cekinović Grbeša

Journal: J Virol Methods

PubMed ID: 33930473

Doi: 10.1016/j.jviromet.2021.114173

Products & Services: Protein Reagents and Products

A role for PAK1 mediated phosphorylation of β-catenin Ser552 in the regulation of insulin secretion

Authors: Brie Sorrenson, Waruni C Dissanayake, Fengyun Hu, Kate L Lee, Peter R Shepherd

Journal: Biochem J

PubMed ID: 33605402

Doi: 10.1042/BCJ20200862

Products & Services: Recombinant Proteins

Identification and Characterization of Zika Virus NS5 Methyltransferase Inhibitors

Authors: Weibao Song, Hongjuan Zhang, Yu Zhang, Ying Chen, Yuan Lin, Yanxing Han, Jiandong Jiang

Journal: Front Cell Infect Microbiol

PubMed ID: 33898335

Doi: 10.3389/fcimb.2021.665379

Products & Services: Recombinant Proteins

Pathological Hyperinsulinemia and Hyperglycemia in the Impaired Glucose Tolerance Stage Mediate Endothelial Dysfunction Through miR-21, PTEN/AKT/eNOS, and MARK/ET-1 Pathways

Authors: Ran Liu, Shilin Guan, Zhongai Gao, Jingyu Wang, Jie Xu, Zhaohu Hao, Yi Zhang, Shaohua Yang, Zhenhong Guo, Juhong Yang, Hailin Shao, Baocheng Chang

Journal: Front Endocrinol (Lausanne)

PubMed ID: 33967958

Doi: 10.3389/fendo.2021.644159

Products & Services: Recombinant Proteins

Menin-regulated Pbk controls high fat diet-induced compensatory beta cell proliferation

Authors: Jian Ma, Bowen Xing, Yan Cao, Xin He, Kate E Bennett, Chao Tong, Chiying An, Taylor Hojnacki, Zijie Feng, Sunbin Deng, Sunbin Ling, Gengchen Xie, Yuan Wu, Yue Ren, Ming Yu, Bryson W Katona, Hongzhe Li, Ali Naji, Xianxin Hua

Journal: EMBO Mol Med

PubMed ID: 33821572

Doi: 10.15252/emmm.202013524

Products & Services: Proteins, Expression, Isolation and Analysis

Cytotoxic Effects and Intracellular Localization of Bin Toxin from in Human Liver Cancer Cell Line

Authors: Simab Kanwal, Shalini Abeysinghe, Monrudee Srisaisup, Panadda Boonserm

Journal: Toxins (Basel)

PubMed ID: 33921797

Doi: 10.3390/toxins13040288

Products & Services: Proteins, Expression, Isolation and Analysis

Structure, Immunoreactivity, and In Silico Epitope Determination of SmSPI Serpin for Immunodiagnostic Application

Authors: Stefano De Benedetti, Flavio Di Pisa, Enrico Mario Alessandro Fassi, Marina Cretich, Angelo Musicò, Roberto Frigerio, Alessandro Mussida, Mauro Bombaci, Renata Grifantini, Giorgio Colombo, Martino Bolognesi, Romualdo Grande, Nadia Zanchetta, Maria Rita Gismondo, Davide Mileto, Alessandro Mancon, Louise Jane Gourlay

Journal: Vaccines (Basel)

PubMed ID: 33915716

Doi: 10.3390/vaccines9040322

Products & Services: Proteins, Expression, Isolation and Analysis

In Vitro and In Vivo Evaluation of a Small-Molecule APJ (Apelin Receptor) Agonist, BMS-986224, as a Potential Treatment for Heart Failure

Authors: Peter Gargalovic, Pancras Wong, Joelle Onorato, Heather Finlay, Tao Wang, Mujing Yan, Earl Crain, Stéphane St-Onge, Madeleine Héroux, Michel Bouvier, Carrie Xu, Xue-Qing Chen, Claudia Generaux, Michael Lawrence, Ruth Wexler, David Gordon

Journal: Circ Heart Fail

PubMed ID: 33663236

Doi: 10.1161/CIRCHEARTFAILURE.120.007351

Products & Services: Recombinant Proteins