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PCC-0105002, a novel small molecule inhibitor of PSD95-nNOS protein-protein interactions, attenuates neuropathic pain and corrects motor disorder associated with neuropathic pain model

Authors: Zhihong Sun, Ping Meng, Chunyu Su, Shengmin Ji, Yonglin Gao, Hongbo Wang, Jingwei Tian, Chunmei Li

Journal: Toxicol Appl Pharmacol

PubMed ID: 34428447

Doi: 10.1016/j.taap.2021.115698

Products & Services: Protein and Antibody Isolation

Performance comparison of micro-neutralization assays based on surrogate SARS-CoV-2 and WT SARS-CoV-2 in assessing virus-neutralizing capacity of anti-SARS-CoV-2 antibodies

Authors: Inna Sekirov, Martin Petric, Erin Carruthers, David Lawrence, Tamara Pidduck, Jesse Kustra, Jonathan Laley, Min-Kuang Lee, Navdeep Chahil, Annie Mak, Paul N Levett, Emelissa Mendoza, Heidi Wood, Mike Drebot, Mel Krajden, Muhammad Morshed

Journal: Access Microbiol

PubMed ID: 34888485

Doi: 10.1099/acmi.0.000257

Products & Services: Recombinant Proteins

3D culture system to study collective migration in mammary organoid epithelium

Authors: Yunzhe Lu, Ruolan Deng, Huanyang You, Pengfei Lu

Journal: STAR Protoc

PubMed ID: 34485944

Doi: 10.1016/j.xpro.2021.100778

Products & Services: Recombinant Proteins

The pro-regenerative effects of hyperIL6 in drug-induced liver injury are unexpectedly due to competitive inhibition of IL11 signaling

Authors: Jinrui Dong, Sivakumar Viswanathan, Eleonora Adami, Sebastian Schafer, Fathima F Kuthubudeen, Anissa A Widjaja, Stuart A Cook

Journal: Elife

PubMed ID: 34435951

Doi: 10.7554/eLife.68843

Products & Services: Recombinant Proteins

Systematic profiling of DNMT3A variants reveals protein instability mediated by the DCAF8 E3 ubiquitin ligase adaptor

Authors: Yung-Hsin Huang, Chun-Wei Chen, Venkatasubramaniam Sundaramurthy, Mikolaj Slabicki, Dapeng Hao, Caroline J Watson, Ayala Tovy, Jaime M Reyes, Olga Dakhova, Brielle R Crovetti, Christina Galonska, Minjung Lee, Lorenzo Brunetti, Yubin Zhou, Katrina Tatton-Brown, Yun Huang, Xiaodong Cheng, Alexander Meissner, Peter J M Valk, Lionel Van Maldergem, Mathijs A Sanders, Jamie R Blundell, Wei Li, Benjamin L Ebert, Margaret A Goodell

Journal: Cancer Discov

PubMed ID: 34429321

Doi: 10.1158/2159-8290.CD-21-0560

Products & Services: Protein and Antibody Isolation

Hsp40s play complementary roles in the prevention of tau amyloid formation

Authors: Rose Irwin, Ofrah Faust, Ivana Petrovic, Sharon Grayer Wolf, Hagen Hofmann, Rina Rosenzweig

Journal: Elife

PubMed ID: 34369377

Doi: 10.7554/eLife.69601

Products & Services: Protein and Antibody Isolation

Self-assembling synthetic nanoadjuvant scaffolds cross-link B cell receptors and represent new platform technology for therapeutic antibody production

Authors: Sujata Senapati, Ross J Darling, Kathleen A Ross, Michael J Wannemeuhler, Balaji Narasimhan, Surya K Mallapragada

Journal: Sci Adv

PubMed ID: 34348905

Doi: 10.1126/sciadv.abj1691

Products & Services: Protein and Antibody Isolation

Comparative phylogenetic analysis of CBL reveals the gene family evolution and functional divergence in Saccharum spontaneum

Authors: Xiaomin Feng, Yongjun Wang, Nannan Zhang, Shuai Gao, Jiayun Wu, Rui Liu, Yonghong Huang, Jisen Zhang, Yongwen Qi

Journal: BMC Plant Biol

PubMed ID: 34425748

Doi: 10.1186/s12870-021-03175-3

Products & Services: Protein Tools

Recombinant Antigens Based on Non-Glycosylated Regions from RBD SARS-CoV-2 as Potential Vaccine Candidates against COVID-19

Authors: Leandro Núñez-Muñoz, Gabriel Marcelino-Pérez, Berenice Calderón-Pérez, Miriam Pérez-Saldívar, Karla Acosta-Virgen, Hugo González-Conchillos, Brenda Vargas-Hernández, Ana Olivares-Martínez, Roberto Ruiz-Medrano, Daniela Roa-Velázquez, Edgar Morales-Ríos, Jorge Ramos-Flores, Gustavo Torres-Franco, Diana Peláez-González, Jorge Fernández-Hernández, Martha Espinosa-Cantellano, Diana Tapia-Sidas, José Abrahan Ramírez-Pool, América Padilla-Viveros, Beatriz Xoconostle-Cázares

Journal: Vaccines (Basel)

PubMed ID: 34452053

Doi: 10.3390/vaccines9080928

Products & Services: Recombinant Proteins

Identification and in-silico characterization of taxadien-5α-ol-O-acetyltransferase (TDAT) gene in Corylus avellana L

Authors: Mona Raeispour Shirazi, Sara Alsadat Rahpeyma, Sajad Rashidi Monfared, Jafar Zolala, Azadeh Lohrasbi-Nejad

Journal: PLoS ONE

PubMed ID: 34449796

Doi: 10.1371/journal.pone.0256704

Products & Services: Protein Tools