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Development of a recombinant Ang1 variant with enhanced Tie2 binding and its application to attenuate sepsis in mice

Authors: Rui Wang , Hao Li , Zhinuo Xie , Meijuan Huang , Peng Xu , Cai Yuan , Jinyu Li , Robert Flaumenhaft , Mingdong Huang , Longguang Jiang

Journal: SCIENCE ADVANCES

PubMed ID: 39813336

Doi: 10.1126/sciadv.ads1796

Products & Services: Protein and Antibody Isolation

Macrophage-specific in vivo RNA editing promotes phagocytosis and antitumor immunity in mice

Authors: Yuxuan Chen , Xiaohong Chen , Yao Zhang , Meng Wang , Minqi Yang , Ruiji Wang , Xiaojie Yan , Shiyi Shao , Huhu Xin , Qida Hu , Wei Wei , Yuan Ping

Journal: Sci Transl Med

PubMed ID: 39813319

Doi: 10.1126/scitranslmed.adl5800

Products & Services: Recombinant Proteins

Delivery of FGF18 using mRNA-LNP protects the cartilage against degeneration via alleviating chondrocyte senescence

Authors: Keyu Kong, Baixing Li, Yongyun Chang, Chen Zhao, Hua Qiao, Minghao Jin, Xinru Wu, Wenxuan Fan, Liao Wang, Yansong Qi, Yongsheng Xu, Zanjing Zhai, Peixiang Ma, Huiwu Li

Journal: Journal of nanobiotechnology

PubMed ID: 39844298

Doi: 10.1186/s12951-025-03103-9

Products & Services: Recombinant Proteins

Mouse totipotent blastomere-like cells model embryogenesis from zygotic genome activation to post implantation

Authors: Bing Peng , Qingyi Wang , Feixiang Zhang , Hui Shen , Peng Du

Journal: Cell Stem Cell

PubMed ID: 39826539

Doi: doi.org/10.1016/j.stem.2024.12.006

Products & Services: Protein Electrophoresis and Western

TMT-Based Quantitative Proteomic Profiling of Human Esophageal Cancer Cells Reveals the Potential Mechanism and Potential Therapeutic Targets Associated With Radioresistance

Authors: Aidi Gao , Chao He , Hengrui Chen , Qianlin Liu , Yin Chen , Jianying Sun , Chuanfeng Wu , Ya Pan , Sonia Rocha , Mu Wang , Jundong Zhou

Journal: Proteomics Clin Appl

PubMed ID: 39375892

Doi: 10.1002/prca.202400010

Products & Services: Protein Electrophoresis and Western

A high-definition spatiotemporal transcriptomic atlas of mammalian kidney development

Authors: Shan Jiang, Hao Yu, Ting Zhao, Yao Lu, Xuesong Li, Lei Gao, Jie Mi, Wenzhe Xia, Lanjun Geng, Panpan Li, Mingyue Chen, Mengyao Kang, Jiang Liu, Yuwen Ke

Journal: The Innovation

Doi: doi.org/10.1016/j.xinn.2024.100767

Products & Services: CRISPR RNAs/Cas9 Proteins(INACTIVE)

Increasing brain half-life of antibodies by additional binding to myelin oligodendrocyte glycoprotein, a CNS specific protein

Authors: Marie-Lynn Cuypers; Tom Jaspers; Jarne Clerckx; Simon Leekens; Christopher Cawthorne; Guy Bormans; Frederik Cleeren; Nick Geukens; Bart De Strooper; Maarten Dewilde

Journal: Fluids and barriers of the CNS

PubMed ID: 39885527

Doi: 10.1186/s12987-025-00624-1

Products & Services: Protein and Antibody Isolation

Self-Cascaded Pyroptosis-STING Initiators for Catalytic Metalloimmunotherapy

Authors: Qiao Yu, Shumin Sun, Nailin Yang, Zifan Pei, Youdong Chen, Jihu Nie, Huali Lei, Li Wang, Fei Gong, Liang Cheng

Journal: Journal of the American Chemical Society

PubMed ID: 39818788

Doi: 10.1021/jacs.4c12552

Products & Services: Protein Electrophoresis and Western

Structural insights into the mechanism of phosphate recognition and transport by XPR1

Authors: Wenhui Zhang, Yanke Chen, Zeyuan Guan, Yong Wang, Meng Tang, Zhangmeng Du, Jie Zhang, Meng Cheng, Jiaqi Zuo, Yan Liu, Qiang Wang, Yanjun Liu, Delin Zhang, Ping Yin, Ling Ma & Zhu Liu

Journal: Nature Communications

PubMed ID: 39747008

Doi: 10.1038/s41467-024-55471-9

Products & Services: Protein and Antibody Isolation

Increased SOAT2 expression in aged regulatory T cells is associated with altered cholesterol metabolism and reduced anti-tumor immunity

Authors: Mingjiong Zhang, Jiahua Cui, Haoyan Chen, Yifan Cheng, Qiaoyu Chen, Feng Zong, Xiao Lu, Lang Qin, Yu Han, Xingwang Kuai, Yuxing Zhang, Minjie Chu, Shuangshuang Wu & Jianqing Wu

Journal: Nature Communications

PubMed ID: 39805872

Doi: 10.1038/s41467-025-56002-w

Products & Services: Protein and Antibody Reagents