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Immunizations with diverse sarbecovirus receptor-binding domains elicit SARS-CoV-2 neutralizing antibodies against a conserved site of vulnerability

Authors: Deborah L Burnett, Katherine J L Jackson, David B Langley, Anupria Aggrawal, Alberto Ospina Stella, Matt D Johansen, Harikrishnan Balachandran, Helen Lenthall, Romain Rouet, Gregory Walker, Bernadette M Saunders, Mandeep Singh, Hui Li, Jake Y Henry, Jennifer Jackson, Alastair G Stewart, Franka Witthauer, Matthew A Spence, Nicole G Hansbro, Colin Jackson, Peter Schofield, Claire Milthorpe, Marianne Martinello, Sebastian R Schulz, Edith Roth, Anthony Kelleher, Sean Emery, Warwick J Britton, William D Rawlinson, Rudolfo Karl, Simon Schäfer, Thomas H Winkler, Robert Brink, Rowena A Bull, Philip M Hansbro, Hans-Martin Jäck, Stuart Turville, Daniel Christ, Christopher C Goodnow

Journal: Immunity

PubMed ID: 34788600

Doi: 10.1016/j.immuni.2021.10.019

Products & Services: Proteins, Expression, Isolation and Analysis

Limited impact of Delta variantâ€™s mutations in the effectiveness of neutralization conferred by natural infection or COVID-19 vaccines in a Latino population

Authors: Carlos A Sariol, Crisanta Serrano-Collazo, Edwin J Ortiz, Petraleigh Pantoja, Lorna Cruz, Teresa Arana, Dianne Atehortua, Christina Pabon-Carrero, Ana M Espino

Journal: medrxiv

PubMed ID: 34729566

Doi: 10.1101/2021.10.25.21265422

Products & Services: Recombinant Proteins

Rational engineering of a functional CpG-free ITR for AAV gene therapy

Authors: Xiufang Pan, Yongping Yue, Maria Boftsi, Lakmini P Wasala, Ngoc Tam Tran, Keqing Zhang, David J Pintel, Phillip W L Tai, Dongsheng Duan

Journal: Gene Ther

PubMed ID: 34611321

Doi: 10.1038/s41434-021-00296-0

Products & Services: Recombinant Proteins

Comprehensive Analysis of Transcriptome-wide mA Methylome Upon Beta2 Toxin Exposure in Porcine Intestinal Epithelial Cells by mA Sequencing

Authors: Juanli Zhang, Qiaoli Yang, Jiaojiao Yang, Xiaoli Gao, Ruirui Luo, Xiaoyu Huang, Zunqiang Yan, Pengfei Wang, Wei Wang, Kaihui Xie, Bo Zhang, Shuangbao Gun

Journal: Front Genet

PubMed ID: 34737761

Doi: 10.3389/fgene.2021.689748

Products & Services: Proteins, Expression, Isolation and Analysis

Structural basis of the P4B ATPase lipid flippase activity

Authors: Lin Bai, Bhawik K Jain, Qinglong You, H Diessel Duan, Mehmet Takar, Todd R Graham, Huilin Li

Journal: Nat Commun

PubMed ID: 34645814

Doi: 10.1038/s41467-021-26273-0

Products & Services: Proteins, Expression, Isolation and Analysis

Effect of Structural Changes Induced by Deletion of 54FLRAPSWF61 Sequence in αB-Crystallin on Chaperone Function and Anti-Apoptotic Activity

Authors: Sundararajan Mahalingam, Srabani Karmakar 1ORCID, Puttur Santhoshkumar, Krishna K. Sharma

Journal: International Journal of Molecular Sciences

PubMed ID: 34639110

Doi: 10.3390/ijms221910771

Products & Services: Proteins, Expression, Isolation and Analysis

TNF-Mediated Inhibition of Classical Swine Fever Virus Replication Is IRF1-, NF-κB- and JAK/STAT Signaling-Dependent

Authors: Matthias Liniger, Markus Gerber, Sandra Renzullo, Obdulio García-Nicolás, Nicolas Ruggli

Journal: Viruses

PubMed ID: 34696447

Doi: 10.3390/v13102017

Products & Services: Proteins, Expression, Isolation and Analysis

Corrigendum to "Rapid preparation of nanodiscs for biophysical studies" [Arch Biochem Biophys 712 (2021) 109051]

Authors: Jeffrey A Julien, Martin G Fernandez, Katrina M Brandmier, Joshua T Del Mundo, Carol M Bator, Lucie A Loftus, Esther W Gomez, Enrique D Gomez, Kerney Jebrell Glover

Journal: Arch Biochem Biophys

PubMed ID: 34756727

Doi: 10.1016/j.abb.2021.109073

Products & Services: Proteins, Expression, Isolation and Analysis

Dynamics of Post-Translational Modification Inspires Drug Design in the Kinase Family

Authors: Huimin Zhang, Jixiao He, Guang Hu, Fei Zhu, Hao Jiang, Jing Gao, Hu Zhou, Hua Lin, Yingjuan Wang, Kaixian Chen, Fanwang Meng, Minghong Hao, Kehao Zhao, Cheng Luo, Zhongjie Liang

Journal: J Med Chem

PubMed ID: 34668699

Doi: 10.1021/acs.jmedchem.1c01076

Products & Services: Proteins, Expression, Isolation and Analysis

Phase separation of Nur77 mediates celastrol-induced mitophagy by promoting the liquidity of p62/SQSTM1 condensates

Authors: Shuang-Zhou Peng, Xiao-Hui Chen, Si-Jie Chen, Jie Zhang, Chuan-Ying Wang, Wei-Rong Liu, Duo Zhang, Ying Su, Xiao-Kun Zhang

Journal: Nat Commun

PubMed ID: 34645818

Doi: 10.1038/s41467-021-26295-8

Products & Services: Proteins, Expression, Isolation and Analysis