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Oral subunit SARS-CoV-2 vaccine induces systemic neutralizing IgG, IgA and cellular immune responses and can boost neutralizing antibody responses primed by an injected vaccine

Authors: Jacob Pitcovski, Nady Gruzdev, Anna Abzach, Chen Katz, Ran Ben-Adiva, Michal Brand-Shwartz, Itamar Yadid, Einav Ratzon-Ashkenazi, Ken Emquies, Hadasa Israeli, Hadar Haviv, Irena Rapoport, Itai Bloch, Roy Shadmon, Zohar Eitan, Dalia Eliahu, Talia Hilel, Morris Laster, Sigal Kremer-Tal, Tamara Byk-Tennenbaum, Ehud Shahar

Journal: Vaccine

PubMed ID: 35078662

Doi: 10.1016/j.vaccine.2022.01.025

Products & Services: Protein and Antibody Isolation

Protocol for structure determination of SARS-CoV-2 main protease at near-physiological-temperature by serial femtosecond crystallography

Authors: Fatma Betul Ertem, Omur Guven, Cengizhan Buyukdag, Oktay Gocenler, Esra Ayan, Busra Yuksel, Mehmet Gul, Gozde Usta, Barıs Cakılkaya, J Austin Johnson, E Han Dao, Zhen Su, Frederic Poitevin, Chun Hong Yoon, Christopher Kupitz, Brandon Hayes, Mengning Liang, Mark S Hunter, Alexander Batyuk, Raymond G Sierra, Gihan Ketawala, Sabine Botha, Çağdaş Dağ, Hasan DeMirci

Journal: STAR Protoc

PubMed ID: 35194584

Doi: 10.1016/j.xpro.2022.101158

Products & Services: Protein and Antibody Isolation

Anion binding to a cationic europium(III) probe enables the first real-time assay of heparan sulfotransferase activity

Authors: Simon Wheeler, Colum Breen, Yong Li, Sarah H Hewitt, Erin Robertson, Edwin A Yates, Igor L Barsukov, David G Fernig, Stephen J Butler

Journal: Org Biomol Chem

PubMed ID: 34951618

Doi: 10.1039/d1ob02071d

Products & Services: Protein and Antibody Isolation

Genome-wide analysis and transcriptional reprogrammings of MYB superfamily revealed positive insights into abiotic stress responses and anthocyanin accumulation in Carthamus tinctorius L

Authors: Yingqi Hong, Naveed Ahmad, Jianyi Zhang, Yanxi Lv, Xinyue Zhang, Xintong Ma, Liu Xiuming, Yao Na

Journal: Mol Genet Genomics

PubMed ID: 34978004

Doi: 10.1007/s00438-021-01839-1

Products & Services: Protein Tools

Single-conformation spectroscopy of cold, protonated PG-containing peptides: switching β-turn types and formation of a sequential type II/II' double β-turn

Authors: John T Lawler, Christopher P Harrilal, Andrew F DeBlase, Edwin L Sibert, Scott A McLuckey, Timothy S Zwier

Journal: Phys Chem Chem Phys

PubMed ID: 35019911

Doi: 10.1039/d1cp04852j

Products & Services: Protein and Antibody Isolation

Development of a radioiodinated thioflavin-T-Congo-red hybrid probe for diagnosis of systemic amyloidosis

Authors: Yoshie Haratake, Kohei Sano, Miki Tsuchiya, Kaori Minaki, Masayuki Munekane, Toshihide Yamasaki, Masayori Hagimori, Takahiro Mukai

Journal: Bioorg Med Chem

PubMed ID: 35033883

Doi: 10.1016/j.bmc.2021.116591

Products & Services: Protein and Antibody Isolation

Ginkgolic acids inhibit SARS-CoV-2 and its variants by blocking the spike protein/ACE2 interplay

Authors: Yusen Xiang, Guanglei Zhai, Yaozong Li, Mengge Wang, Xixiang Chen, Ruyu Wang, Hang Xie, Weidong Zhang, Guangbo Ge, Qian Zhang, Yechun Xu, Amedeo Caflisch, Jianrong Xu, Hongzhuan Chen, Lili Chen

Journal: Int J Biol Macromol

PubMed ID: 36521705

Doi: 10.1016/j.ijbiomac.2022.12.057

Products & Services: Recombinant Proteins

RBD conjugate vaccine with a built-in TLR1/2 agonist is highly immunogenic against SARS-CoV-2 and variants of concern

Authors: Shi-Hao Zhou 1 , Ru-Yan Zhang, Hai-Wei Zhang, Yan-Ling Liu, Yu Wen, Jian Wang, Yu-Ting Li, Zi-Wei You, Xu-Guang Yin, Hong Qiu, Rui Gong, Guang-Fu Yang, Jun Guo

Journal: Chem Commun (Camb)

PubMed ID: 35040862

Doi: 10.1039/d1cc06520c

Products & Services: Catalog Peptides Catalog Antibodies Recombinant Proteins

Computer-Informed Engineering a New Class I Sesquiterpene Synthase JeSTS4 for the Synthesis of Unusual C10-(S)- Bicyclogermacrene

Authors: Xiaoguang Yan, Jiahui Zhou, Jianjun Ge, Weiguo Li, Dongmei Liang, Warispreet Singh, Gary Black, Shengxin Nie, Jian Liu, Meiqing Sun, Jianjun Qiao, and Meilan Huang

Journal: ACS catalysis

Doi: 10.1021/acscatal.2c00013

Products & Services: Protein and Antibody Isolation

Proline-specific aminopeptidase P prevents replication-associated genome instability

Authors: Nicola Silva, Maikel Castellano-Pozo, Kenichiro Matsuzaki, Consuelo Barroso, Monica Roman-Trufero, Hannah Craig, Darren R Brooks, R Elwyn Isaac, Simon J Boulton, Enrique Martinez-Perez

Journal: PLoS Genet

PubMed ID: 35081133

Doi: 10.1371/journal.pgen.1010025

Products & Services: Protein and Antibody Isolation