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Dengue virus downregulates TNFR1- and TLR3-stimulated NF-κB activation by targeting RIPK1

Authors: Darshika J Udawatte, Diane M Lang, Jeffrey R Currier, Carey L Medin, Alan L Rothman

Journal: Front Cell Infect Microbiol

PubMed ID: 36310878

Doi: 10.3389/fcimb.2022.926036

Products & Services: Recombinant Proteins

BP5 alleviates endotoxemia-induced acute lung injury by activating Nrf2 via dual regulation of the Keap1-Nrf2 interaction and the Akt (Ser473)/GSK3β (Ser9)/Fyn pathway

Authors: Tianxiang Li, Zhirong Geng, Ju Zhang, Lu Xu, Xiaoli Zhu

Journal: Free Radic Biol Med

PubMed ID: 36272670

Doi: 10.1016/j.freeradbiomed.2022.10.299

Products & Services: Recombinant Proteins

Apigenin suppresses mycoplasma-induced alveolar macrophages necroptosis via enhancing the methylation of TNF-α promoter by PPARγ-Uhrf1 axis

Authors: Xiuzhen Mei, Jian Wang, Chao Zhang, Jiale Zhu, Beibei Liu, Qingyun Xie, Ting Yuan, Yuzi Wu, Rong Chen, Xing Xie, Yanna Wei, Li Wang, Guoqing Shao, Qiyan Xiong, Yefen Xu, Zhixin Feng, Zhenzhen Zhang

Journal: Phytomedicine

PubMed ID: 36332388

Doi: 10.1016/j.phymed.2022.154504

Products & Services: Protein and Antibody Isolation

The potential effects and mechanisms of Gegen Qinlian Decoction in oxaliplatin-resistant colorectal cancer based on network pharmacology

Authors: Xiang Lin, Li Xu, Huicheng Tan, Xinyi Zhang, Huan Shao, Li Yao, Xuan Huang

Journal: Heliyon

PubMed ID: 36353164

Doi: 10.1016/j.heliyon.2022.e11305

Products & Services: Protein Electrophoresis and Western

Engineering Self-Assembled Endolysin Nanoparticles against Antibiotic-Resistant Bacteria

Authors: Christian K O Dzuvor, Bhuvana K Shanbhag, Tayyaba Younas, Hsin-Hui Shen, Victoria S Haritos, Lizhong He

Journal: ACS Appl Bio Mater

PubMed ID: 36194892

Doi: 10.1021/acsabm.2c00741

Products & Services: Protein and Antibody Isolation

Differential expression and roles of Huntingtin and Huntingtin-associated protein 1 in the mouse and primate brains

Authors: Xingxing Chen, Yize Sun, Laiqiang Chen, Xiu-Sheng Chen, Mingtian Pan, Yiran Zhang, Qi Wang, Weili Yang, Peng Yin, Dajian He, Xiangyu Guo, Su Yang, Yan Zeng, Sen Yan, Xiao-Jiang Li, Shihua Li

Journal: Cell Mol Life Sci

PubMed ID: 36251080

Doi: 10.1007/s00018-022-04577-8

Products & Services: Protein and Antibody Isolation

Biparatopic nanobodies targeting the receptor binding domain efficiently neutralize SARS-CoV-2

Authors: Phillip Pymm, Samuel J Redmond, Olan Dolezal, Francesca Mordant, Ester Lopez, James P Cooney, Kathryn C Davidson, Ebene R Haycroft, Chee Wah Tan, Rebecca Seneviratna, Samantha L Grimley, Damian F J Purcell, Stephen J Kent, Adam K Wheatley, Lin-Fa Wang, Andrew Leis, Alisa Glukhova, Marc Pellegrini, Amy W Chung, Kanta Subbarao, Adam P Uldrich, Wai-Hong Tham, Dale I Godfrey, Nicholas A Gherardin

Journal: iScience

PubMed ID: 36213007

Doi: 10.1016/j.isci.2022.105259

Products & Services: Protein and Antibody Isolation

EP-Pred: A Machine Learning Tool for Bioprospecting Promiscuous Ester Hydrolases

Authors: Ruite Xiang, Laura Fernandez-Lopez, Ana Robles-Martín, Manuel Ferrer, Victor Guallar

Journal: Biomolecules

PubMed ID: 36291739

Doi: 10.3390/biom12101529

Products & Services: Recombinant Proteins

Dynamic HIV-1 spike motion creates vulnerability for its membrane-bound tripod to antibody attack

Authors: Shuang Yang, Giorgos Hiotis, Yi Wang, Junjian Chen, Jia-Huai Wang, Mikyung Kim, Ellis L Reinherz, Thomas Walz