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Leveraging a Structural Blueprint to Rationally Engineer the Rieske Oxygenase TsaM

Authors: Jiayi Tian, Alejandro Arcadio Garcia, Patrick H Donnan, Jennifer Bridwell-Rabb

Journal: Biochemistry

PubMed ID: 37188334

Doi: 10.1021/acs.biochem.3c00150

Products & Services: Protein and Antibody Isolation

Topically Administered NOX4 Inhibitor, GLX7013114, Is Efficacious in Treating the Early Pathological Events of Diabetic Retinopathy

Authors: Stavroula Dionysopoulou, Per Wikstrom, Claudio Bucolo, Giovanni Luca Romano, Vincenzo Micale, Richard Svensson, Dimitris Spyridakos, Niki Mastrodimou, Spiros Georgakis, Panayotis Verginis, Erik Walum, Kyriaki Thermos

Journal: Diabetes

PubMed ID: 36821829

Doi: 10.2337/db22-0515

Products & Services: Protein and Antibody Isolation

The Nucleocapsid Proteins of SARS-CoV-2 and Its Close Relative Bat Coronavirus RaTG13 Are Capable of Inhibiting PKR- and RNase L-Mediated Antiviral Pathways

Authors: Kyle LeBlanc, Jessie Lynch, Christine Layne, Robert Vendramelli, Angela Sloan, Nikesh Tailor, Yvon Deschambault, Fushun Zhang, Darwyn Kobasa, David Safronetz, Yan Xiang, Jingxin Cao

Journal: Microbiol Spectr

PubMed ID: 37154717

Doi: 10.1128/spectrum.00994-23

Products & Services: Protein and Antibody Isolation

Functionalized Metal–Organic Framework-Modified Hydrogel That Breaks the Vicious Cycle of Inflammation and ROS for Repairing of Diabetic Bone Defects

Authors: An Lao, Jiaqing Wu, Dejian Li, Aili Shen, Yaxin Li, Yu Zhuang, Kaili Lin, Jianyong Wu, Jiaqiang Liu

Journal: Small

PubMed ID: 37183293

Doi: smll.202206919

Products & Services: Protein and Antibody Isolation

Co-delivery of Cas9 mRNA and guide RNAs edits hepatitis B virus episomal and integration DNA in mouse and tree shrew models

Authors: Junzhu Yi, Xinlin Lei, Fangteng Guo, Qiubing Chen, Xueyong Chen, Kaitao Zhao, Chengliang Zhu, Xiaoming Cheng, Jiangwei Lin, Hao Yin, Yuchen Xia

Journal: Antiviral research

PubMed ID: 37142191

Doi: 10.1016/j.antiviral.2023.105618

Products & Services: CRISPR RNAs/Cas9 Proteins(INACTIVE)

CLASPs stabilize the pre-catastrophe intermediate state between microtubule growth and shrinkage

Authors: Elizabeth J Lawrence, Saptarshi Chatterjee, Marija Zanic

Journal: J Cell Biol

PubMed ID: 37184584

Doi: 10.1083/jcb.202107027

Products & Services: Protein and Antibody Isolation

JNK3 Overexpression in the Entorhinal Cortex Impacts on the Hippocampus and Induces Cognitive Deficiencies and Tau Misfolding

Authors: Carlos G Ardanaz, Amaia Ezkurdia, Arantza Bejarano, Beatriz Echarte, Cristian Smerdou, Eva Martisova, Iván Martínez-Valbuena, María-Rosario Luquin, María J Ramírez, Maite Solas

Journal: ACS Chem Neurosci

PubMed ID: 37236204

Doi: 10.1021/acschemneuro.3c00092

Products & Services: Protein and Antibody Isolation

Computational engineering of previously crystallized pyruvate formate-lyase activating enzyme reveals insights into SAM binding and reductive cleavage

Authors: James D Moody, Sarah Hill, Maike N Lundahl, Aubrianna J Saxton, Amanda Galambas, William E Broderick, C Martin Lawrence, Joan B Broderick

Journal: J Biol Chem

PubMed ID: 37156396

Doi: 10.1016/j.jbc.2023.104791

Products & Services: Protein and Antibody Isolation

Vesicular Stomatitis Virus (VSV) G Glycoprotein Can Be Modified to Create a Her2/Neu-Targeted VSV That Eliminates Large Implanted Mammary Tumors

Authors: Yanhua Gao, Ira Bergman

Journal: J Virol

PubMed ID: 37199666

Doi: 10.1128/jvi.00372-23

Products & Services: Protein and Antibody Isolation

Alpha-synuclein-associated changes in PINK1-PRKN-mediated mitophagy are disease context dependent

Authors: Xu Hou, Taylor Hsuan-Yu Chen, Shunsuke Koga, Jenny M Bredenberg, Ayman H Faroqi, Marion Delenclos, Guojun Bu, Zbigniew K Wszolek, Jonathan A Carr, Owen A Ross, Pamela J McLean, Melissa E Murray, Dennis W Dickson, Fabienne C Fiesel, Wolfdieter Springer

Journal: Brain Pathol

PubMed ID: 37259617

Doi: 10.1111/bpa.13175

Products & Services: Protein and Antibody Isolation