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CRISPR-ChIP reveals selective regulation of H3K79me2 by Menin in MLL leukemia

Authors: Omer Gilan, Laure Talarmain, Charles C Bell, Daniel Neville, Kathy Knezevic, Daniel T Ferguson, Marion Boudes, Yih-Chih Chan, Chen Davidovich, Enid Y N Lam, Mark A Dawson

Journal: Nat Struct Mol Biol

PubMed ID: 37679565

Doi: 10.1038/s41594-023-01087-4

Products & Services: Protein and Antibody Isolation

The cryo-EM-delineated mechanism underlying mimicry of CXCR4 agonism enables widespread stem cell neuroprotection in a mouse model of ALS

Authors: Xiaohong Sang; Haizhan Jiao; Qian Meng; Xiong Fang; Kartik S. Sundaram; Jiao Zhou; Yan Xu; Asuka I. W. Alvarado; Ruslan L. Nuryyev; Jitka Ourenik; Vaclav Ourednik; Iris S. Huang; Xiang Liu; Yuheng Mei; Tingli Qian; Aaron Ciechanover; Donald P. Pizzo; Michael A. Lane; Lyandysha V. Zholudeva; Jing An; Evan Y. Snyder; Hongli Hu; Ziwei Huang

Journal: biorxiv

PubMed ID: 40672153

Doi: 10.1101/2025.07.08.663251

Products & Services: Protein and Antibody Isolation

TgLaforin, a glucan phosphatase, reveals the dynamic role of storage polysaccharides in tachyzoites and bradyzoites

Authors: Robert D Murphy, Cortni A Troublefield, Joy S Miracle, Lyndsay E A Young, Corey O Brizzee, Animesh Dhara, Ramon C Sun, Craig W Vander Kooi, Matthew S Gentry, Anthony P Sinai

Journal: biorxiv

PubMed ID: 37808860

Doi: 10.1101/2023.09.29.560185

Products & Services: Protein and Antibody Isolation

Optimizing effector functions of monoclonal antibodies via tailored N-glycan engineering using a dual landing pad CHO targeted integration platform

Authors: Ngan T B Nguyen, Hau Wan Leung, Kuin Tian Pang, Shi Jie Tay, Ian Walsh, Andre B H Choo, Yuansheng Yang

Journal: Sci Rep

PubMed ID: 37731040

Doi: 10.1038/s41598-023-42925-1

Products & Services: Protein and Antibody Isolation

Loss of function of FIGNL1, a DNA damage response gene, causes human ovarian dysgenesis

Authors: Natan Florsheim, Larisa Naugolni, Fouad Zahdeh, Orit Lobel, Batel Terespolsky, Rachel Michaelson-Cohen, Merav Y Gold, Michal Goldberg, Paul Renbaum, Ephrat Levy-Lahad, David Zangen

Journal: Eur J Endocrinol

PubMed ID: 37740949

Doi: 10.1093/ejendo/lvad127

Products & Services: Protein and Antibody Isolation

Is the co-option of jasmonate signalling for botanical carnivory universal trait for all carnivorous plants?

Authors: Andrej Pavlovič, Jana Koller, Ondřej Vrobel, Ivo Chamrád, René Lenobel, Peter Tarkowski

Journal: J Exp Bot

PubMed ID: 37708289

Doi: 10.1093/jxb/erad359

Products & Services: Protein and Antibody Isolation

Acute and Long-Term Consequences of Co-opted doublesex on the Development of Mimetic Butterfly Color Patterns

Authors: Nicholas W VanKuren, Meredith M Doellman, Sofia I Sheikh, Daniela H Palmer Droguett, Darli Massardo, Marcus R Kronforst

Journal: Mol Biol Evol

PubMed ID: 37668300

Doi: 10.1093/molbev/msad196

Products & Services: Protein and Antibody Isolation

Short N-terminal disordered regions and the proline-rich domain are major regulators of phase transitions for full-length UBQLN1, UBQLN2 and UBQLN4

Authors: Thuy P Dao, Anitha Rajendran, Sarasi K K Galagedera, William Haws, Carlos A Castañeda

Journal: biorxiv

PubMed ID: 37808720

Doi: 10.1101/2023.09.27.559790

Products & Services: Protein and Antibody Isolation

Enhancing CAR T-cell Therapy Using Fab-Based Constitutively Heterodimeric Cytokine Receptors

Authors: Matteo Righi, Isaac Gannon, Matthew Robson, Saket Srivastava, Evangelia Kokalaki, Thomas Grothier, Francesco Nannini, Christopher Allen, Yuchen V Bai, James Sillibourne, Shaun Cordoba, Simon Thomas, Martin Pule

Journal: Cancer Immunol Res

PubMed ID: 37352396

Doi: 10.1158/2326-6066.CIR-22-0640

Products & Services: Protein and Antibody Isolation

Mechanistic insights into nucleosomal H2B monoubiquitylation mediated by yeast Bre1-Rad6 and its human homolog RNF20/RNF40-hRAD6A

Authors: Zhiheng Deng, Huasong Ai, Maoshen Sun, Zebin Tong, Yunxiang Du, Qian Qu, Liying Zhang, Ziyu Xu, Shixian Tao, Qiang Shi, Jia-Bin Li, Man Pan, Lei Liu

Journal: Mol Cell

PubMed ID: 37633270

Doi: 10.1016/j.molcel.2023.08.001

Products & Services: Protein and Antibody Isolation