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DNAJB6 mutants display toxic gain of function through unregulated interaction with Hsp70 chaperones

Authors: Meital Abayev-Avraham, Yehuda Salzberg, Dar Gliksberg, Meital Oren-Suissa, Rina Rosenzweig

Journal: Nat Commun

PubMed ID: 37923706

Doi: 10.1038/s41467-023-42735-z

Products & Services: Proteins, Expression, Isolation and Analysis

Regulated secretion of mutant p53 negatively affects T lymphocytes in the tumor microenvironment

Authors: Xiang Dong, Chunlu Li, Chengsi Deng, Jingwei Liu, Danni Li, Tingting Zhou, Xindi Yang, Yunchan Liu, Qiqiang Guo, Yanling Feng, Yang Yu, Zhuo Wang, Wendong Guo, Siyi Zhang, Hongyan Cui, Cui Jiang, Xiwen Wang, Xiaoyu Song, Xun Sun, Liu Cao

Journal: Oncogene

PubMed ID: 37952080

Doi: 10.1038/s41388-023-02886-1

Products & Services: Proteins, Expression, Isolation and Analysis

Conserved antigen structures and antibody-driven variations on foot-and-mouth disease virus serotype A revealed by bovine neutralizing monoclonal antibodies

Authors: Kun Li, Yong He, Li Wang, Pinghua Li, Huifang Bao, Shulun Huang, Shasha Zhou, Guoqiang Zhu, Yali Song, Ying Li, Sheng Wang, Qianliang Zhang, Pu Sun, Xingwen Bai, Zhixun Zhao, Zhiyong Lou, Yimei Cao, Zengjun Lu, Zaixin Liu

Journal: PLoS Pathog

PubMed ID: 37983290

Doi: 10.1371/journal.ppat.1011811

Products & Services: Proteins, Expression, Isolation and Analysis

Interactions of Histone Deacetylase 6 with DNA Damage Repair Factors Strengthen its Utility as a Combination Drug Target in High-Grade Serous Ovarian Cancer

Authors: Jolene M Duda, Stefani N Thomas

Journal: ACS Pharmacol Transl Sci

PubMed ID: 38107255

Doi: 10.1021/acsptsci.3c00215

Products & Services: Proteins, Expression, Isolation and Analysis

Environment relevant exposure of perfluorooctanoic acid accelerates the growth of hepatocellular carcinoma cells through mammalian target of rapamycin (mTOR) signal pathway

Authors: Jiawei Hong, Xiaoyan Wang, Hangbiao Jin, Yuanchen Chen, Yifan Jiang, Keyi Du, Diyu Chen, Shusen Zheng, Linping Cao

Journal: Environ Pollut

PubMed ID: 37967710

Doi: 10.1016/j.envpol.2023.122910

Products & Services: Proteins, Expression, Isolation and Analysis

Molecular basis for the catalytic mechanism of human neutral sphingomyelinases 1 (hSMPD2)

Authors: Jingbo Yi, Boya Qi, Jian Yin, Ruochong Li, Xudong Chen, Junhan Hu, Guohui Li, Sensen Zhang, Yuebin Zhang, Maojun Yang

Journal: Nat Commun

PubMed ID: 38012235

Doi: 10.1038/s41467-023-43580-w

Products & Services: Proteins, Expression, Isolation and Analysis

An mRNA-based platform for the delivery of pathogen-specific IgA into mucosal secretions

Authors: Cailin E Deal, Angelene F Richards, Tracy Yeung, Max J Maron, Ziqiu Wang, Yen-Ting Lai, Brian R Fritz, Sunny Himansu, Elisabeth Narayanan, Ding Liu, Rositsa Koleva, Stuart Licht, Chiaowen J Hsiao, Ivana L Rajlic, Hillary Koch, Michael Kleyman, Mark E Pulse, William J Weiss, Jennifer E Doering, Samantha K Lindberg, Nicholas J Mantis, Andrea Carfi, Obadiah J Plante

Journal: Cell Rep Med

PubMed ID: 37918405

Doi: 10.1016/j.xcrm.2023.101253

Products & Services: Proteins, Expression, Isolation and Analysis

Low-sugar universal mRNA vaccine against coronavirus variants with deletion of glycosites in the S2 or stem of SARS-CoV-2 spike messenger RNA (mRNA)

Authors: Cheng-Wei Cheng, Chung-Yi Wu, Szu-Wen Wang, Jia-Yan Chen, Chih-Chuan Kung, Kuo-Shiang Liao, Chi-Huey Wong

Journal: Proc Natl Acad Sci U S A

PubMed ID: 38011546

Doi: 10.1073/pnas.2314392120

Products & Services: Proteins, Expression, Isolation and Analysis

Development of a sandwich ELISA to detect circulating, soluble IRAP as a potential disease biomarker

Authors: Anika Vear, Claudia Thalmann, Kristina Youngs, Natalie Hannan, Tracey Gaspari, Siew Yeen Chai

Journal: Sci Rep

PubMed ID: 38001104

Doi: 10.1038/s41598-023-44038-1

Products & Services: Proteins, Expression, Isolation and Analysis

Effect of Neutralizing Monoclonal Antibody Treatment on Early Trajectories of Virologic and Immunologic Biomarkers in Patients Hospitalized With COVID-19

Authors: Tomas O Jensen, Greg A Grandits, Mamta K Jain, Thomas A Murray, Birgit Grund, Kathryn Shaw-Saliba, Michael A Matthay, Mahsa Abassi, Magdalena Ardelt, Jason V Baker, Peter Chen, Robin L Dewar, Anna L Goodman, Timothy J Hatlen, Helene C Highbarger, Mark Holodniy, Perrine Lallemand, Sylvain Laverdure, Bradley G Leshnower, David Looney, Charalampos D Moschopoulos, Henry Mugerwa, Daniel D Murray, Eleftherios Mylonakis, Stephanie Nagy-Agren, M Tauseef Rehman, Adam Rupert, Randy A Stevens, Stuart Turville, Amy Weintrob, Katherine Wick, Jens Lundgren, Emily R Ko

Journal: J Infect Dis

PubMed ID: 37948759

Doi: 10.1093/infdis/jiad446

Products & Services: Proteins, Expression, Isolation and Analysis

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