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Inhibition of Exo-miR-19a-3p derived from cardiomyocytes promotes angiogenesis and improves heart function in mice with myocardial infarction via targeting HIF-1α
Authors: Lianping Gou, Cheng Xue, Xiaoyan Tang, Zhiyuan Fang
Journal: Aging (Albany NY)
PubMed ID: 33352533
Doi: 10.18632/aging.103563
Development of Second Generation Activity-Based Chemical Probes for Sirtuins
Authors: Alyson M Curry, Elizabeth Barton, Wenjia Kang, Daniel V Mongeluzi, Yana Cen
Journal: Molecules
PubMed ID: 33375102
Doi: 10.3390/molecules26010011
Alternative AKT2 splicing produces protein lacking the hydrophobic motif regulatory region
Authors: Guido Plotz, Laura A Lopez-Garcia, Angela Brieger, Stefan Zeuzem, Ricardo M Biondi
Journal: PLoS ONE
PubMed ID: 33253205
Doi: 10.1371/journal.pone.0242819
Methylmercury chloride exposure aggravates proinflammatory mediators and Notch-1 signaling in CD14 and CD40 cells and is associated with imbalance of neuroimmune function in BTBR T Itpr3tf/J mice
Authors: Sheikh F Ahmad, Saleh A Bakheet, Mushtaq A Ansari, Ahmed Nadeem, Abdulelah F Alobaidi, Sabry M Attia, Abdullah S Alhamed, Abdullah A Aldossari, Mohamed A Mahmoud
Journal: Neurotoxicology
PubMed ID: 33166615
Doi: 10.1016/j.neuro.2020.10.014
Reoxygenation induces reactive oxygen species production and ferroptosis in renal tubular epithelial cells by activating aryl hydrocarbon receptor
Authors: Theodoros Eleftheriadis, Georgios Pissas, Georgios Filippidis, Vassilios Liakopoulos, Ioannis Stefanidis
Journal: Mol Med Rep
PubMed ID: 33179104
Doi: 10.3892/mmr.2020.11679
A catalogue of biochemically diverse CRISPR-Cas9 orthologs
Authors: Gasiunas G, Young JK, Karvelis T, Kazlauskas D, Urbaitis T, Jasnauskaite M, Grusyte MM, Paulraj S, Wang PH, Hou Z, Dooley SK, Cigan M, Alarcon C, Chilcoat ND, Bigelyte G, Curcuru JL, Mabuchi M, Sun Z, Fuchs RT, Schildkraut E, Weigele PR, Jack WE, Robb GB, Venclovas Č, Siksnys V
Journal: Nature Communications
PubMed ID: 33139742
Doi: 10.1038/s41467-020-19344-1
Equine lentivirus counteracts SAMHD1 restriction by Rev-mediated degradation of SAMHD1 via the BECN1-dependent lysosomal pathway
Authors: Ren H,Yin X,Su C,Guo M,Wang XF,Na L,Lin Y,Wang X
Journal: Autophagy
PubMed ID: 33172327
Doi: 10.1080/15548627.2020.1846301
Human Urinal Cell Reprogramming: Synthetic 3D Peptide Hydrogels Enhance Induced Pluripotent Stem Cell Population Homogeneity
Authors: Sun W,Zhang S,Zhou T,Shan Y,Gao F,Zhang Y,Zhang D,Xiong Y,Mai Y,Fan K,Davidson AJ,Pan G,Zhang X
Journal: ACS Biomaterials Science & Engineering
PubMed ID: 33449655
Doi: 10.1021/acsbiomaterials.0c00667
Manumycin polyketides act as molecular glues between UBR7 and P53
Authors: Isobe Y,Okumura M,McGregor LM,Brittain SM,Jones MD,Liang X,White R,Forrester W,McKenna JM,Tallarico JA,Schirle M,Maimone TJ,Nomura DK
Journal: Nature Chemical Biology
PubMed ID: 32572277
Doi: 10.1038/s41589-020-0557-2
PAR2 induces ovarian cancer cell motility by merging three signalling pathways to transactivate EGFR
Authors: Yuhong Jiang, Junxian Lim, Kai-Chen Wu, Weijun Xu, Jacky Y Suen, David P Fairlie
Journal: Br J Pharmacol
PubMed ID: 33226635
Doi: 10.1111/bph.15332

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