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A potent and selective PARP14 inhibitor decreases protumor macrophage gene expression and elicits inflammatory responses in tumor explants

Authors: Laurie B Schenkel, Jennifer R Molina, Kerren K Swinger, Ryan Abo, Danielle J Blackwell, Alvin Z Lu, Anne E Cheung, W David Church, Kaiko Kunii, Kristy G Kuplast-Barr, Christina R Majer, Elena Minissale, Jan-Rung Mo, Mario Niepel, Christopher Reik, Yue Ren, Melissa M Vasbinder, Tim J Wigle, Victoria M Richon, Heike Keilhack, Kevin W Kuntz

Journal: Cell Chem Biol

PubMed ID: 33705687

Doi: 10.1016/j.chembiol.2021.02.010

Products & Services: Proteins, Expression, Isolation and Analysis

Micro/nano-textured hierarchical titanium topography promotes exosome biogenesis and secretion to improve osseointegration

Authors: Zhengchuan Zhang, Ruogu Xu, Yang Yang, Chaoan Liang, Xiaolin Yu, Yun Liu, Tianlu Wang, Yi Yu, Feilong Deng

Journal: J Nanobiotechnology

PubMed ID: 33741002

Doi: 10.1186/s12951-021-00826-3

Products & Services: Proteins, Expression, Isolation and Analysis

Electronegative very-low-density lipoprotein induces brain inflammation and cognitive dysfunction in mice

Authors: Ying-Shao Lin, Ching-Kuan Liu, Hsiang-Chun Lee, Mei-Chuan Chou, Liang-Yin Ke, Chu-Huang Chen, Shiou-Lan Chen

Journal: Sci Rep

PubMed ID: 33727609

Doi: 10.1038/s41598-021-85502-0

Products & Services: Proteins, Expression, Isolation and Analysis

Single-cell RNA sequencing reveals that targeting HSP90 suppresses PDAC progression by restraining mitochondrial bioenergetics

Authors: Li-Peng Hu, Kai-Xia Zhou, Yan-Miao Huo, De-Jun Liu, Qing Li, Min-Wei Yang, Pei-Qi Huang, Chun-Jie Xu, Guang-Ang Tian, Lin-Li Yao, Xue-Li Zhang, Ya-Hui Wang, Jun Li, Zhi-Gang Zhang, Shu-Heng Jiang, Xin Xing, Xu Wang, Wei-Ting Qin, Qin Yang

Journal: Oncogenesis

PubMed ID: 33658487

Doi: 10.1038/s41389-021-00311-4

Products & Services: Proteins, Expression, Isolation and Analysis

Biophysical and biochemical properties of Deup1 self-assemblies: a potential driver for deuterosome formation during multiciliogenesis

Authors: Shohei Yamamoto, Ryoichi Yabuki, Daiju Kitagawa

Journal: Biol Open

PubMed ID: 33658185

Doi: 10.1242/bio.056432

Products & Services: Proteins, Expression, Isolation and Analysis

KCa31 Inhibition of Macrophages Suppresses Inflammatory Response Leading to Endothelial Damage in a Cell Model of Kawasaki Disease

Authors: Fenglei Zheng, Yijing Tao, Jingjing Liu, Zhimin Geng, Ying Wang, Yujia Wang, Songling Fu, Wei Wang, Chunhong Xie, Yiying Zhang, Fangqi Gong