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DUSP22 dephosphorylates LGALS1 to enhance T cell-driven antitumor immunity

Authors: Lijian Wang, Yutong Guo, Yujie Dai, Wangsheng Sun, Xiaoying Huang, Haipeng Lei, Aiping Zhang, Shuwen Chen, Yiting Li, Jiani Pan, Yangjian Hong, Lingchuan Ma, Yangyang Feng, Fangyuan Shao, Jianming Zeng, Peng Luo, Junqi Li, Weiting Chen, Na Zhou, Yang Li, Heng Sun, Xiaoling Xu, Chu-Xia Deng, Kai Miao

Journal: Journal for ImmunoTherapy of Cancer

PubMed ID: 41611244

Doi: 10.1136/jitc-2025-013142

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A recurrent pathogenic BRCA2 truncating variant reveals a role for BRCA2-PCAF complex in modulating NF-κB-driven transcription

Authors: Anna Minello, Jesus Gomez-Escudero, Sreerama Chaitanya Sridhara, Charlotte Martin, Elodie Girard, Juan C Cañas, Yasin Memari, Maria Rose Bustos, Antonio Galarreta, Virginie Boucherit, Evgeny Imyanitov, Sigridur Klara Bodvarsdottir, Sylvain Baulande, Anne Vincent-Salomon, Nicolas Servant, Matthias Altmeyer, Stefan Sigurdsson, Dominique Stoppa-Lyonnet, Serena Nik-Zainal, Aura Carreira

Journal: Nature Communications

PubMed ID: 41372141

Doi: 10.1038/s41467-025-67209-2

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The prion-like characteristic of ORF3 contributes to virion release and pathogenesis of hepatitis E virus

Authors: Yajing Wang, Houlu Tian, Na Shi, Chunyan Wu, Yaowei Huang, Yongling Yang, Qiang Ding, Xu Zheng, Qin Zhao, Zhaonong Hu, Jiaojiao Luo, Lele Feng, Lingdong Xu, Mick F Tuite, Hongying Chen, Yuchen Nan

Journal: Proceedings of the National Academy of Sciences of the United States of America

PubMed ID: 41343667

Doi: 10.1073/pnas.2511801122

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Control of Mycobacterium tuberculosis protein secretion by ESX-4 and the outer membrane EsxUT-EsxEF complex

Authors: Rashmi Ravindran Nair, Virginia Meikle, Swati Dubey, Mikhail Pavlenok, Anna D Tischler, Michael Niederweis

Journal: Nature Communications

PubMed ID: 41266320

Doi: 10.1038/s41467-025-65061-y.

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Planthopper protein Nlsp5 is essential for salivary sheath formation and acts as a HAMP inducing plant resistance to insects

Authors: Liangxuan Qi, Jing Li, Han Wang, Shuai Li, Lei Yang, Jichao Fang, Rui Ji

Journal: Plant Biotechnology Journal

PubMed ID: 40546084

Doi: DOI10.1111/pbi.70223

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Insights into type IX secretion from PorKN cogwheel structure bound to PorG and attachment complexes

Authors: Dhana G Gorasia, Eric Hanssen, Manasi Mudaliyar, Craig J Morton, Sepideh Valimehr, Christine Seers, Lianyi Zhang, Matthew T Doyle, Debnath Ghosal, Paul D Veith, Eric C Reynolds

Journal: Nature Communications

PubMed ID: 40830366

Doi: 10.1038/s41467-025-63163-1.

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Control of Golgi- V-ATPase through Sac1-dependent co-regulation of PI(4)P and cholesterol

Authors: Xin Zhou, Miesje M van der Stoel, Shreyas Kaptan, Haoran Li, Shiqian Li, Maarit Hölttä, Helena Vihinen, Eija Jokitalo, Christoph Thiele, Olli Pietiläinen, Shin Morioka, Junko Sasaki, Takehiko Sasaki, Ilpo Vattulainen, Elina Ikonen

Journal: Nature Communications

PubMed ID: 40841558

Doi: 10.1038/s41467-025-63125-7.

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The cAMP-PKA signaling initiates mitosis by phosphorylating Bora

Authors: Min Zhu, Shinan Zhou, Yingqi Zhang, Qinfu Chen, Xueying Yuan, Long Zhang, Haiyan Yan, Fangwei Wang

Journal: Nature Communications

PubMed ID: 40849432

Doi: 10.1038/s41467-025-63352-y.

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Iron-sulfur clusters in SARS-CoV-2 exoribonuclease and methyltransferase complexes: relevance for viral genome proofreading and capping

Authors: Nunziata Maio, Umberto Terranova, Yan Li, J Martin Bollinger Jr, Carsten Krebs, Tracey A Rouault