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miR-223 in exosomes from bone marrow mesenchymal stem cells ameliorates rheumatoid arthritis via downregulation of NLRP3 expression in macrophages

Authors: Ying Huang, Daomin Lu, Wukai Ma, Jun Liu, Qiaoyi Ning, Fang Tang, Long Li

Journal: Mol Immunol

PubMed ID: 35042119

Doi: 10.1016/j.molimm.2022.01.002

Products & Services: Gene Synthesis

Anagliptin prevents lipopolysaccharide (LPS)- induced inflammation and activation of macrophages

Authors: Fangfang Yu, Wenxia Tian, Jie Dong

Journal: Int Immunopharmacol

PubMed ID: 35045357

Doi: 10.1016/j.intimp.2021.108514

Products & Services: Gene Synthesis

Silencing of circCDC14A prevents cerebral ischemia-reperfusion injury via miR-23a-3p/CXCL12 axis

Authors: Huiyi Huo, Chao Hu, Yongxue Lu, Jinyu Zhou, Zhiguang Mai

Journal: J Biochem Mol Toxicol

PubMed ID: 34978116

Doi: 10.1002/jbt.22982

Products & Services: Gene Synthesis

The Predictive Efficacy of Serum Exosomal microRNA-122 and microRNA-148a for Hepatocellular Carcinoma Based on Smart Healthcare

Authors: Peng Deng, Mi Li, Yuni Wu

Journal: J Healthc Eng

PubMed ID: 35028121

Doi: 10.1155/2022/5914541

Products & Services: Gene Synthesis

Functionality of a bicistronic construction containing and genes encoding β-hexosaminidase A for cell-mediated therapy of GM2 gangliosidoses

Authors: Alisa A Shaimardanova, Daria S Chulpanova, Valeriya V Solovyeva, Aleksandr M Aimaletdinov, Albert A Rizvanov

Journal: Neural Regen Res

PubMed ID: 34100447

Doi: 10.4103/1673-5374.314310

Products & Services: Gene Synthesis

Molecular Basis for the Substrate Promiscuity of Isopentenyl Phosphate Kinase from Candidatus methanomethylophilus alvus

Authors: Bryce P Johnson , Vikas Kumar , Erin M Scull , Leonard M Thomas , Christina R Bourne , Shanteri Singh

Journal: ACS Chem Biol

PubMed ID: 34905349

Doi: 10.1021/acschembio.1c00655

Products & Services: Gene Synthesis

Deletion of Specific Conserved Motifs from the N-Terminal Domain of B-Crystallin Results in the Activation of Chaperone Functions

Authors: Sundararajan Mahalingam Goutham Shankar, Brian P. Mooney, Kamal Singh, Puttur Santhoshkumar, and Krishna K. Sharma

Journal: International Journal of Molecular Sciences

Doi: 10.3390/ijms23031099

Products & Services: Gene Synthesis Gene Synthesis

Measurement of deaminated cytosine adducts in DNA using a novel hybrid thymine DNA glycosylase

Authors: Chia Wei Hsu, Mark L Sowers, Tuvshintugs Baljinnyam, Jason L Herring, Linda C Hackfeld, Hui Tang, Kangling Zhang, Lawrence C Sowers

Journal: J Biol Chem

PubMed ID: 35085553

Doi: 10.1016/j.jbc.2022.101638

Products & Services: Gene Synthesis

Efficacy and immunogenicity of MultiTEP-based DNA vaccines targeting human α-synuclein: prelude for IND enabling studies

Authors: Changyoun Kim, Armine Hovakimyan, Karen Zagorski, Tatevik Antonyan, Irina Petrushina, Hayk Davtyan, Gor Chailyan, Jonathan Hasselmann, Michiyo Iba, Anthony Adame, Edward Rockenstein, Marcell Szabo, Mathew Blurton-Jones, David H Cribbs, Anahit Ghochikyan, Eliezer Masliah, Michael G Agadjanyan

Journal: npj Vaccines

PubMed ID: 35013319

Doi: 10.1038/s41541-021-00424-2

Products & Services: Gene Synthesis

In vivo spatiotemporal control of voltage-gated ion channels by using photoactivatable peptidic toxins

Authors: Jérôme Montnach, Laila Ananda Blömer, Ludivine Lopez, Luiza Filipis, Hervé Meudal, Aude Lafoux, Sébastien Nicolas, Duong Chu, Cécile Caumes, Rémy Béroud, Chris Jopling, Frank Bosmans, Corinne Huchet, Céline Landon, Marco Canepari, Michel De Waard

Journal: Nat Commun

PubMed ID: 35058427

Doi: 10.1038/s41467-022-27974-w

Products & Services: Gene Synthesis