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Activation of the TGFβ pathway impairs endothelial to haematopoietic transition.

Authors: Vargel Ö, Zhang Y, Kosim K, Ganter K, Foehr S, Mardenborough Y, Shvartsman M, Enright AJ, Krijgsveld J, Lancrin C.

Journal: Sci Rep

PubMed ID: 26891705

Doi: 10.1038/srep21518

Products & Services: Gene Synthesis

Evolved Repression Overcomes Enhancer Robustness.

Authors: Preger-Ben Noon E, Davis FP, Stern DL.

Journal: Dev Cell

PubMed ID: 27840106

Doi: 10.1016/j.devcel.2016.10.010

Products & Services: Gene Synthesis

Aryl hydrocarbon receptor-dependent apoptotic cell death induced by the flavonoid chrysin in human colorectal cancer cells.

Authors: Ronnekleiv-Kelly SM, Nukaya M, Díaz-Díaz CJ, Megna BW, Carney PR, Geiger PG, Kennedy GD.

Journal: Cancer Lett

PubMed ID: 26515162

Doi: 10.1016/j.canlet.2015.10.014

Products & Services: Gene Synthesis

Genome-wide siRNA Screening at Biosafety Level 4 Reveals a Crucial Role for Fibrillarin in Henipavirus Infection.

Authors: Deffrasnes C, Marsh GA, Foo CH, Rootes CL, Gould CM, Grusovin J, Monaghan P, Lo MK, Tompkins SM, Adams TE, Lowenthal JW,, Simpson KJ,, Stewart CR, Bean AG, Wang LF,.

Journal: PLoS Pathog

PubMed ID: 27010548

Doi: 10.1371/journal.ppat.1005478

Products & Services: Gene Synthesis

Kynurenine-3-monooxygenase inhibition prevents multiple organ failure in rodent models of acute pancreatitis.

Authors: Mole DJ,, Webster SP, Uings I, Zheng X, Binnie M, Wilson K, Hutchinson JP, Mirguet O, Walker A, Beaufils B, Ancellin N, Trottet L, Bénéton V, Mowat CG, Wilkinson M, Rowland P, Haslam C, McBride A, Homer NZ, Baily JE, Sharp MG, Garden OJ, Hughes J, Howie SE, Holmes DS, Liddle J, Iredale JP.

Journal: Nat Med

PubMed ID: 26752518

Doi: 10.1038/nm.4020

Products & Services: Gene Synthesis

Atypical natural killer T-cell receptor recognition of CD1d-lipid antigens.

Authors: Le Nours J,, Praveena T, Pellicci DG,, Gherardin NA,, Ross FJ,, Lim RT, Besra GS, Keshipeddy S, Richardson SK, Howell AR, Gras S,, Godfrey DI,, Rossjohn J,,, Uldrich AP,.

Journal: Nat Commun

PubMed ID: 26875526

Doi: 10.1038/ncomms10570

Products & Services: Gene Synthesis

Sam68 Is Required for DNA Damage Responses via Regulating Poly(ADP-ribosyl)ation.

Authors: Sun X, Fu K, Hodgson A, Wier EM, Wen MG, Kamenyeva O, Xia X, Koo LY, Wan F,,.

Journal: PLoS Biol

PubMed ID: 27635653

Doi: 10.1371/journal.pbio.1002543

Products & Services: Gene Synthesis

Streptococcus pyogenes quinolinate-salvage pathway-structural and functional studies of quinolinate phosphoribosyl transferase and NH3 -dependent NAD+ synthetase

Authors: Booth WT, Morris TL, Mysona DP, Shah MJ, Taylor LK, Karlin TW, Clary K, Majorek KA, Offermann LR, Chruszcz M.

Journal: FEBS J

PubMed ID: 28618168

Doi: 10.1111/febs.14136

Products & Services: Gene Synthesis

In Vitro Antiviral Activity and Resistance Profile Characterization of the Hepatitis C Virus NS5A Inhibitor Ledipasvir.

Authors: Cheng G, Tian Y, Doehle B, Peng B, Corsa A, Lee YJ, Gong R, Yu M, Han B, Xu S, Dvory-Sobol H, Perron M, Xu Y, Mo H, Pagratis N, Link JO, Delaney W.

Journal: Antimicrob Agents Chemother.

PubMed ID: 26824950

Products & Services: Gene Synthesis

Antibody Response to Hypervariable Region 1 Interferes with Broadly Neutralizing Antibodies to Hepatitis C Virus

Authors: Keck ZY, Girard-Blanc C, Wang W, Lau P, Zuiani A, Rey FA, Krey T, Diamond MS, Foung SK

Journal: Journal of Virology

PubMed ID: 26739044

Doi: 10.1128/JVI.02458-15

Products & Services: Gene Synthesis