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Rapid and tunable method to temporally control gene editing based on conditional Cas9 stabilization.

Authors: SenturkSerif，ShiroleNitin H，NowakDawid G，CorboVincenzo，PalDebjani，VaughanAlexander，TuvesonDavid A，TrotmanLloyd C，KinneyJustin B，SordellaRaffa

Journal: Nat Commun

PubMed ID: 28224990

Doi: 10.1038/ncomms14370

Products & Services: Codon Optimization Gene Synthesis

Caulobacter crescentus CdnL is a non-essential RNA polymerase-binding protein whose depletion impairs normal growth and rRNA transcription

Authors: Aránzazu Gallego-García , Antonio A Iniesta , Diego González , Justine Collier , S Padmanabhan , Montserrat Elías-Arnanz

Journal: Sci Rep

PubMed ID: 28233804

Doi: 10.1038/srep43240

Products & Services: Gene Synthesis

Highly multiplex and sensitive SNP genotyping method using a three-color fluorescence-labeled ligase detection reaction coupled with conformation-sensitive CE.

Authors: ChoiWoong, JungGyoo

Journal: Electrophoresis

PubMed ID: 27754559

Doi: 10.1002/elps.201600369

Products & Services: Gene Synthesis

CRISPR/Cas9-Mediated Genome Editing as a Therapeutic Approach for Leber Congenital Amaurosis 10.

Authors: RuanGuo-Xiang, BarryElizabeth, YuDan, LukasonMichael, ChengSeng H, ScariaAbr

Journal: Mol. Ther.

PubMed ID: 28109959

Doi: 10.1016/j.ymthe.2016.12.006

Products & Services: Gene Synthesis

A chimera containing CD4+ and CD8+ T-cell epitopes of the Leishmania donovani-nucleoside hydrolase NH36 optimizes cross-protection against Leishmania amazonesis infection.

Authors: Alves-Silva MV, Nico D, Morrot A, Palatnik M, Palatnik-de-Sousa CB.

Journal: Front Immunol

PubMed ID: 28280494

Doi: 10.3389/fimmu.2017.00100

Products & Services: Gene Synthesis Peptide Synthesis

Substrate-analogous inhibitors exert antimalarial action by targeting the Plasmodium lactate transporter PfFNT at nanomolar scale.

Authors: Golldack A, Henke B, Bergmann B, Wiechert M, Erler H, Blancke Soares A, Spielmann T, Beitz E.

Journal: PLoS Pathog.

PubMed ID: 28178358

Products & Services: Gene Synthesis

FHF2 isoforms differentially regulate Nav16-mediated resurgent sodium currents in dorsal root ganglion neurons

Authors: BarbosaCindy, XiaoYucheng, JohnsonAndrew J, XieWenrui, StrongJudith A, ZhangJun-Ming, CumminsTheodo

Journal: Pflugers Arch.

PubMed ID: 27999940

Doi: 10.1007/s00424-016-1911-9

Products & Services: Gene Synthesis

Tetramethylpyrazine attenuates carbon tetrachloride-caused liver injury and fibrogenesis and reduces hepatic angiogenesis in rats

Authors: ZhaoShifeng, ZhangZili, QianLinnan, LinQiuyi, ZhangChenxi, ShaoJiangjuan, ZhangFeng, ZhengShiz

Journal: Biomed. Pharmacother.

PubMed ID: 28024287

Doi: 10.1016/j.biopha.2016.11.122

Products & Services: Gene Synthesis

KCNMA1 cooperating with PTK2 is a novel tumor suppressor in gastric cancer and is associated with disease outcome

Authors: MaGaoxiang, LiuHanting, HuaQiuhan, WangMeilin, DuMulong, LinYadi, GeYuqiu, GongWeida, ZhaoQinghong, QiangFulin, TaoGuoquan, ZhangZhengdong, ChuHa

Journal: Mol. Cancer

PubMed ID: 28231797

Doi: 10.1186/s12943-017-0613-z

Products & Services: Gene Synthesis

Bioinformatic prediction and functional characterization of human KIAA0100 gene

Authors: CuiHe, LanXi, LuShemin, ZhangFujun, ZhangWang

Journal: J Pharm Anal

PubMed ID: 29404013

Doi: 10.1016/j.jpha.2016.09.003

Products & Services: Gene Synthesis