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Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes

Authors: Zebin Tong , Huasong Ai, Ziyu Xu , Kezhang He , Guo-Chao Chu, Qiang Shi , Zhiheng Deng, Qiaomei Xue , Maoshen Sun, Yunxiang Du , Lujun Liang, Jia-Bin Li , Man Pan , Lei Liu

Journal: Nat Struct Mol Biol .

PubMed ID: 38177667

Doi: 10.1038/s41594-023-01141-1

Products & Services: Protein Electrophoresis and Western Gene Synthesis

LL‐37_Renalexin hybrid peptide exhibits antimicrobial activity at lower MICs than its counterpart single peptides

Authors: Julius Kwesi Narh , Nestor G Casillas-Vega , Xristo Zarate

Journal: Appl Microbiol Biotechnol .

PubMed ID: 38229302

Doi: 10.1007/s00253-023-12887-5

Products & Services: Gene Synthesis

High-Yield Expression and Purification of Scygonadin, an Antimicrobial Peptide, Using the Small Metal-Binding Protein SmbP

Authors: Jessica J. Gomez-Lugo 1 , Nestor G. Casillas-Vega , Alma Gomez-Loredo , Isaias Balderas-Renteria and Xristo Zarate

Journal: Microorganisms

Doi: 10.3390/microorganisms12020278

Products & Services: Gene Synthesis

Affinity-assisted covalent self-assembly of PduQ-SpyTag and Nox-SpyCatcher to construct multi-enzyme complexes on the surface of magnetic microsphere modified with chelated Ni

Authors: Mianxing Luo, Meng Zhang, Changbiao Chi, Guo Chen

Journal: Int J Biol Macromol

PubMed ID: 38218263

Doi: 10.1016/j.ijbiomac.2024.129365

Products & Services: Gene Synthesis

Recombinantly expressed virus-like particles (VLPs) of canine circovirus for development of an indirect ELISA

Authors: Alison Neef, Babu Kanti Nath, Tridip Das, Daniel Luque, Jade K Forwood, Shane R Raidal, Shubhagata Das

Journal: Vet Res Commun

PubMed ID: 38163840

Doi: 10.1007/s11259-023-10290-z

Products & Services: Gene Synthesis

A small-molecule activation mechanism that directly opens the KCNQ2 channel

Authors: Shaoying Zhang, Demin Ma, Kun Wang, Ya Li, Zhenni Yang, Xiaoxiao Li, Junnan Li, Jiangnan He, Lianghe Mei, Yangliang Ye, Zongsheng Chen, Juwen Shen, Panpan Hou, Jiangtao Guo, Qiansen Zhang, Huaiyu Yang

Journal: Nat Chem Biol

PubMed ID: 38167918

Doi: 10.1038/s41589-023-01515-y

Products & Services: Gene Synthesis

Revamped mini-αA-crystallin showed improved skin permeation and therapeutic activity against melittin-induced toxicity

Authors: Tenzin Tender, Rakesh Ravishankar Rahangdale, Madhavan Nampoothiri, Ruchira Raychaudhuri, Srinivas Mutalik, Krishna Sharma, Raghu Chandrashekar H

Journal: Toxicon

PubMed ID: 38211805

Doi: 10.1016/j.toxicon.2024.107611

Products & Services: Gene Synthesis

An immunocytokine consisting of a TNFR2 agonist and TNFR2 scFv enhances the expansion of regulatory T cells through TNFR2 clustering

Authors: Masaki Inoue, Yuta Tsuji, Ayaka Kashiwada, Asahi Yokoyama, Akane Iwata, Yasuhiro Abe, Haruhiko Kamada, Shin-Ichi Tsunoda

Journal: Biochem Biophys Res Commun

PubMed ID: 38262291

Doi: 10.1016/j.bbrc.2024.149498

Products & Services: Gene Synthesis

Surface-modified measles vaccines encoding oligomeric, prefusion-stabilized SARS-CoV-2 spike glycoproteins boost neutralizing antibody responses to Omicron and historical variants, independent of measles seropositivity

Authors: Miguel Á Muñoz-Alía, Rebecca A Nace, Baskar Balakrishnan, Lianwen Zhang, Nandakumar Packiriswamy, Gagandeep Singh, Prajakta Warang, Ignacio Mena, Riya Narjari, Rianna Vandergaast, Kah-Whye Peng, Adolfo García-Sastre, Michael Schotsaert, Stephen J Russell

Journal: MBio

PubMed ID: 38193729

Doi: 10.1128/mbio.02928-23

Products & Services: Gene Synthesis

Biosynthesis of 10-Hydroxy-2-decenoic Acid through a One-Step Whole-Cell Catalysis

Authors: Ke Fang , Ziting Xu , Lu Yang , Quan Cui , Bowen Du , Huijing Liu , Ruiming Wang , Piwu Li , Jing Su , Junqing Wang

Journal: J Agric Food Chem .

PubMed ID: 38175798

Doi: 10.1021/acs.jafc.3c08142

Products & Services: Gene Synthesis