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Localized delivery of CRISPR/dCas9 via layer-by-layer self-assembling peptide coating on nanofibers for neural tissue engineering

Authors: Kunyu Zhang, Wai Hon Chooi, Shuang Liu, Jiah Shin Chin, Aoife Murray, Dean Nizetic, Du Cheng, Sing Yian Chew

Journal: Biomaterials

PubMed ID: 32738650

Doi: 10.1016/j.biomaterials.2020.120225

Products & Services: Gene Synthesis

Mcl-1-mediated mitochondrial fission protects against stress but impairs cardiac adaptation to exercise

Authors: Alexandra G Moyzis, Navraj S Lally, Wenjing Liang, Leonardo J Leon, Rita H Najor, Amabel M Orogo, Åsa B Gustafsson

Journal: J Mol Cell Cardiol

PubMed ID: 32717194

Doi: 10.1016/j.yjmcc.2020.07.009

Products & Services: Gene Synthesis

New Organometallic Ruthenium(II) Compounds Synergistically Show Cytotoxic, Antimetastatic and Antiangiogenic Activities for the Treatment of Metastatic Cancer

Authors: Yuchen Wang, Jiahui Jin, Liwei Shu, Tongyu Li, Siming Lu, Mohamed Kasim Mohamed Subarkhan, Chao Chen, Hangxiang Wang

Journal: Chemistry

PubMed ID: 32639591

Doi: 10.1002/chem.202002970

Products & Services: Gene Synthesis

New base editors change C to A in bacteria and C to G in mammalian cells

Authors: Dongdong Zhao, Ju Li, Siwei Li, Xiuqing Xin, Muzi Hu, Marcus A Price, Susan J Rosser, Changhao Bi, Xueli Zhang

Journal: Nat Biotechnol

PubMed ID: 32690970

Doi: 10.1038/s41587-020-0592-2

Products & Services: Gene Synthesis

Apremilast regulates acute effects of ethanol and other GABAergic drugs via protein kinase A-dependent signaling

Authors: Yuri A Blednov, Cecilia M Borghese, Michael P Dugan, Swetak Pradhan, Thanvi M Thodati, Nikhita R Kichili, R Adron Harris, Robert O Messing

Journal: Neuropharmacology

PubMed ID: 32736086

Doi: 10.1016/j.neuropharm.2020.108220

Products & Services: Gene Synthesis

Real-time detection of changes in yeast plasma membrane potential using genetically encoded voltage indicator proteins

Authors: Limapichat W, Pornthanakasem W, Satitthammachart C, Chitnumsub P, Leartsakulpanich U

Journal: FEMS yeast research

PubMed ID: 32691845

Doi: 10.1093/femsyr/foaa041

Products & Services: Gene Synthesis

Subtyping analysis reveals new variants and accelerated evolution of Clostridioides difficile toxin B

Authors: Shen E, Zhu K, Li D, Pan Z, Luo Y, Bian Q, He L, Song X, Zhen Y, Jin D, Tao L

Journal: Communications Biology

PubMed ID: 32620855

Doi: 10.1038/s42003-020-1078-y

Products & Services: Gene Synthesis

Histone H33 phosphorylation amplifies stimulation-induced transcription

Authors: Armache A, Yang S, Martínez de Paz A, Robbins LE, Durmaz C, Cheong JQ, Ravishankar A, Daman AW, Ahimovic DJ, Klevorn T, Yue Y, Arslan T, Lin S, Panchenko T, Hrit J, Wang M, Thudium S, Garcia BA, Korb E, Armache KJ, Rothbart SB, Hake SB, Allis CD, Li H, Josefowicz SZ

Journal: Nature

PubMed ID: 32699416

Doi: 10.1038/s41586-020-2533-0

Products & Services: Gene Synthesis

The proofreading activity of Pfprex from Plasmodium falciparum can prevent mutagenesis of the apicoplast genome by oxidized nucleotides

Authors: Sharma M, Narayanan N, Nair DT

Journal: Scientific REPORTS

PubMed ID: 32636411

Doi: 10.1038/s41598-020-67853-2

Products & Services: Gene Synthesis

SOCS3 Attenuates GM-CSF/IFN-γ-Mediated Inflammation During Spontaneous Spinal Cord Regeneration

Authors: Zhang X, He B, Li H, Wang Y, Zhou Y, Wang W, Song T, Du N, Gu X, Luo Y, Wang Y

Journal: Neuroscience bulletin

PubMed ID: 32306216

Doi: 10.1007/s12264-020-00493-8

Products & Services: Gene Synthesis