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COVID-19 vaccine BNT162b1 elicits human antibody and T_H1 T cell responses

Authors: Sahin U, Muik A, Derhovanessian E, Vogler I, Kranz LM, Vormehr M, Baum A, Pascal K, Quandt J, Maurus D, Brachtendorf S, Lörks V, Sikorski J, Hilker R, Becker D, Eller AK, Grützner J, Boesler C, Rosenbaum C, Kühnle MC, Luxemburger U, Kemmer-Brück A, Langer D, Bexon M, Bolte S, Karikó K, Palanche T, Fischer B, Schultz A, Shi PY, Fontes-Garfias C, Perez JL, Swanson KA, Loschko J, Scully IL, Cutler M, Kalina W, Kyratsous CA, Cooper D, Dormitzer PR, Jansen KU, Türeci Ö

Journal: Nature

PubMed ID: 32998157

Doi: 10.1038/s41586-020-2814-7

Products & Services: Gene Synthesis

SIRT1 is downregulated by autophagy in senescence and ageing

Authors: Xu C, Wang L, Fozouni P, Evjen G, Chandra V, Jiang J, Lu C, Nicastri M, Bretz C, Winkler JD, Amaravadi R, Garcia BA, Adams PD, Ott M, Tong W, Johansen T, Dou Z, Berger SL

Journal: Nature Cell Biology

PubMed ID: 32989246

Doi: 10.1038/s41556-020-00579-5

Products & Services: Gene Synthesis

Enzymatic DNA synthesis enters new phase

Authors: Eisenstein M

Journal: Nature Biotechnology

PubMed ID: 33020638

Doi: 10.1038/s41587-020-0695-9

Products & Services: Gene Synthesis

Molecular mechanism underlying selective inhibition of mRNA nuclear export by herpesvirus protein ORF10

Authors: Feng H, Tian H, Wang Y, Zhang Q, Lin N, Liu S, Yu Y, Deng H, Gao P

Journal: Proceedings of the National Academy of Sciences of the United States of America

PubMed ID: 33033226

Doi: 10.1073/pnas.2007774117

Products & Services: Gene Synthesis

Ferric uptake regulator (Fur) reversibly binds a [2Fe-2S] cluster to sense intracellular iron homeostasis in Escherichia coli

Authors: Chelsey R Fontenot , Homyra Tasnim , Kathryn A Valdes , Codrina V Popescu , Huangen Ding

Journal: J Biol Chem

PubMed ID: PMC7667960

Doi: 10.1074

Products & Services: Gene Synthesis

Domain-Specific Antibodies Reveal Differences in the Membrane Topologies of Apolipoprotein L1 in Serum and Podocytes

Authors: Gupta N, Wang X, Wen X, Moran P, Paluch M, Hass PE, Heidersbach A, Haley B, Kirchhofer D, Brezski RJ, Peterson AS, Scales SJ

Journal: Journal of the American Society of Nephrology : JASN

PubMed ID: 32764138

Doi: 10.1681/ASN.2019080830

Products & Services: Gene Synthesis

Nucleolar RNA polymerase II drives ribosome biogenesis

Authors: Abraham KJ, Khosraviani N, Chan JNY, Gorthi A, Samman A, Zhao DY, Wang M, Bokros M, Vidya E, Ostrowski LA, Oshidari R, Pietrobon V, Patel PS, Algouneh A, Singhania R, Liu Y, Yerlici VT, De Carvalho DD, Ohh M, Dickson BC, Hakem R, Greenblatt JF, Lee S, Bishop AJR, Mekhail K

Journal: Nature

PubMed ID: 32669707

Doi: 10.1038/s41586-020-2497-0

Products & Services: Gene Synthesis

Multicopy Targeted Integration for Accelerated Development of High-Producing Chinese Hamster Ovary Cells

Authors: Sergeeva D, Lee GM, Nielsen LK, Grav LM

Journal: ACS Synthetic Biology

PubMed ID: 32835482

Doi: 10.1021/acssynbio.0c00322

Products & Services: Gene Synthesis

Sensitive and reliable evaluation of single-cut sgRNAs to restore dystrophin by a GFP-reporter assay

Authors: Pin Lyu , Kyung Whan Yoo , Manish Kumar Yadav , Anthony Atala , Annemieke Aartsma-Rus , Maaike van Putten , Dongsheng Duan , Baisong Lu

Journal: PLoS ONE

PubMed ID: 32970732

Doi: 10.1371/journal.pone.0239468

Products & Services: Gene Synthesis

Both Boceprevir and GC376 efficaciously inhibit SARS-CoV-2 by targeting its main protease

Authors: Fu L, Ye F, Feng Y, Yu F, Wang Q, Wu Y, Zhao C, Sun H, Huang B, Niu P, Song H, Shi Y, Li X, Tan W, Qi J, Gao GF

Journal: Nature Communications

PubMed ID: 32887884

Doi: 10.1038/s41467-020-18233-x

Products & Services: Gene Synthesis