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FoxO1 is a crucial mediator of TGF-β/TAK1 signaling and protects against osteoarthritis by maintaining articular cartilage homeostasis

Authors: Wang C, Shen J, Ying J, Xiao D, O'Keefe RJ

Journal: Proceedings of the National Academy of Sciences of the United States of America

PubMed ID: 33199631

Doi: 10.1073/pnas.2017056117

Products & Services: Gene Synthesis

High-Throughput Screening for Drugs That Inhibit Papain-Like Protease in SARS-CoV-2

Authors: Smith E, Davis-Gardner ME, Garcia-Ordonez RD, Nguyen TT, Hull M, Chen E, Baillargeon P, Scampavia L, Strutzenberg T, Griffin PR, Farzan M, Spicer TP

Journal: SLAS discovery : advancing life sciences R & D

PubMed ID: 33043784

Doi: 10.1177/2472555220963667

Products & Services: Gene Synthesis

Apremilast interferes with the TGFβ1-induced transition of human skin fibroblasts into profibrotic myofibroblasts: in vitro study

Authors: Cutolo M, Soldano S, Montagna P, Martinelli G, Tardito S, Corallo C, Giordano N, Tavilla P, Cozzani E, Parodi A, Sulli A, Pizzorni C, Patane M, Smith V, Paolino S

Journal: Rheumatology (Oxford, England)

PubMed ID: 32725130

Doi: 10.1093/rheumatology/keaa249

Products & Services: Gene Synthesis

NineTeen Complex-subunit Salsa is required for efficient splicing of a subset of introns and dorsal-ventral patterning.

Authors: Rathore OS,Silva RD,Ascensão-Ferreira M,Matos R,Carvalho C,Marques B,Tiago MN,Prudêncio P,Andrade RP,Roignant JY,Barbosa-Morais NL,Martinho RG

Journal: RNA (New York, N.Y.)

PubMed ID: 32963109

Doi: 10.1261/rna.077446.120

Products & Services: Gene Synthesis

Hepatic Stellate Cells in Hepatocellular Carcinoma Promote Tumor Growth Via Growth Differentiation Factor 15 Production

Authors: Yuta Myojin, Hayato Hikita, Masaya Sugiyama, Yoichi Sasaki, Kenji Fukumoto, Sadatsugu Sakane, Yuki Makino, Nobuyuki Takemura, Ryoko Yamada, Minoru Shigekawa, Takahiro Kodama, Ryotaro Sakamori, Shogo Kobayashi, Tomohide Tatsumi, Hiroshi Suemizu, Hidetoshi Eguchi, Norihiro Kokudo, Masashi Mizokami, Tetsuo Takehara

Journal: Gastroenterology

PubMed ID: 33346004

Doi: 10.1053/j.gastro.2020.12.015

Products & Services: Gene Synthesis

NEase-based amplification for detection of miRNA, multiple miRNAs and circRNA

Authors: Yajun Zhang, Qiuyang Zhang, Xiaocheng Weng, Yuhao Du, Xiang Zhou

Journal: Anal Chim Acta

PubMed ID: 33453881

Doi: 10.1016/j.aca.2020.12.024

Products & Services: Gene Synthesis

Clusterin Protects Lipotoxicity-Induced Apoptosis via Upregulation of Autophagy in Insulin-Secreting Cells

Authors: Seok-Woo Hong, Jinmi Lee, Min Jeong Kim, Sun Joon Moon, Hyemi Kwon, Se Eun Park, Eun-Jung Rhee, Won-Young Lee

Journal: Endocrinol Metab (Seoul)

PubMed ID: 33261311

Doi: 10.3803/EnM.2020.768

Products & Services: Gene Synthesis

Knockdown of lncRNA ANRIL suppresses the production of inflammatory cytokines and mucin 5AC in nasal epithelial cells via the miR-15a-5p/JAK2 axis

Authors: Huo-Wang Liu, Zhong-Liang Hu, Hao Li, Qi-Feng Tan, Jing Tong, Yong-Quan Zhang

Journal: Mol Med Rep

PubMed ID: 33325534

Doi: 10.3892/mmr.2020.11784

Products & Services: Gene Synthesis

MicroRNA-1278 ameliorates the inflammation of cardiomyocytes during myocardial ischemia by targeting both IL-22 and CXCL14

Authors: Donghai Liu, Chenhui Qiao, Hong Luo

Journal: Life Sci

PubMed ID: 33275986

Doi: 10.1016/j.lfs.2020.118817

Products & Services: Gene Synthesis

Identification of SRSF10 as a regulator of SMN2 ISS-N1

Authors: Sabrina B Frederiksen, Lise L Holm, Martin R Larsen, Thomas K Doktor, Henriette S Andersen, Michelle L Hastings, Yimin Hua, Adrian R Krainer, Brage S Andresen

Journal: Hum Mutat

PubMed ID: 33300159

Doi: 10.1002/humu.24149

Products & Services: Gene Synthesis