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Tailorable biosensors for real-time monitoring of stress distribution in soft biomaterials and living tissues

Authors: Fenghou Yuan, Huitang Qi, Binghui Song, Yuntian Cui, Junsheng Zhang, Huan Liu, Bo Liu, Hai Lei, Tian Liu

Journal: nature COMMUNICATION

PubMed ID: 39870637

Doi: doi.org/10.1038/s41467-025-56422-8

Products & Services: Gene Synthesis

Single-cycle parainfluenza virus type 5 vectors for producing recombinant proteins, including a humanized anti-V5 tag antibody

Authors: Richard E Randall , Dan Young , Maria Pisliakova , Jelena Andrejeva , Lynsey West , Luis Rossler , Volker Morath , David Hughes , Steve Goodbourn

Journal: JOURNAL OF GENERAL VIROLOGY

PubMed ID: 39786361

Doi: 10.1099/jgv.0.002061

Products & Services: Gene Synthesis PCR Cloning and Subcloning

Structural and bioinformatics analyses identify deoxydinucleotide-specific nucleases and their association with genomic islands in gram-positive bacteria

Authors: Sofia Mortensen, Stanislava Kuncová, Justin D Lormand, Tanner M Myers, Soo-Kyoung Kim, Vincent T Lee, Wade C Winkler, Holger Sondermann

Journal: Nucleic Acids Research

PubMed ID: 39778863

Doi: 10.1093/nar/gkae1235

Products & Services: Gene Synthesis

Scale-free Spatio-temporal Correlations in Conformational Fluctuations of Intrinsically Disordered Proteins

Authors: Haoyu Song, Jian Cui, Guorong Hu, Long Xiong, Yanee Wutthinitikornkit, Hai Lei, Jingyuan Li

Journal: Advanced Science

PubMed ID: 39807013

Doi: 10.1002/advs.202412989

Products & Services: Gene Synthesis

Regulation of N-degron recognin-mediated autophagy by the SARS-CoV-2 PLpro ubiquitin deconjugase

Authors: Carlos Ayala-Torres , Jiangnan Liu , Nico P Dantuma , Maria G Masucci

Journal: Autophagy

PubMed ID: 39723606

Doi: 10.1080/15548627.2024.2442849

Products & Services: Gene Synthesis

Reconstitution of human DNA licensing and the structural and functional analysis of key intermediates

Authors: Jennifer N. Wells, Lucy V. Edwardes, Vera Leber, Shenaz Allyjaun, Matthew Peach, Joshua Tomkins, Antonia Kefala-Stavridi, Sarah V. Faull, Ricardo Aramayo, Carolina M. Pestana, Lepakshi Ranjha & Christian Speck

Journal: Nature Communications

PubMed ID: 39779677

Doi: 10.1038/s41467-024-55772-z

Products & Services: Gene Synthesis

Screening the human miRNA interactome reveals coordinated up-regulation in melanoma, adding bidirectional regulation to miRNA networks

Authors: Faezeh Jame-Chenarboo , Joseph N Reyes , Nicholas M Twells , Hoi Hei Ng , Dawn Macdonald , Eva Hernando , Lara K Mahal

Journal: SCIENCE ADVANCES

PubMed ID: 39792681

Doi: 10.1126/sciadv.adr0277

Products & Services: Gene Synthesis

Hypoxia-tropic delivery of nanozymes targeting transferrin receptor 1 for nasopharyngeal carcinoma radiotherapy sensitization

Authors: Ruofei Zhang, Yanfang Shen, Xiaoying Zhou, Jianru Li, Hanqing Zhao, Zixia Zhang, Jun Zhao, Hongjun Jin, Shuanshuan Guo, Hui Ding, Guohui Nie, Zhe Zhang, Ying Wang, Xiyun Yan & Kelong Fan

Journal: Nature Communications

PubMed ID: 39837820

Doi: 10.1038/s41467-025-56134-z

Products & Services: Gene Synthesis

A nanobody-enzyme fusion protein targeting PD-L1 and sialic acid exerts anti-tumor effects by C-type lectin pathway-mediated tumor associated macrophages repolarizing

Authors: Yongliang Tong , Runqiu Chen , Xinrong Lu , Cuiying Chen , Guiqin Sun , Xiaolu Yu , Shaoxian Lyu , Meiqing Feng , Yiru Long , Likun Gong , Li Chen

Journal: Int J Biol Macromol

PubMed ID: 39824395

Doi: 10.1016/j.ijbiomac.2025.139953

Products & Services: Gene Synthesis

Restoring tumor antigenicity activates the “bystander” T cell immune cycle

Authors: Yifan Yang , Qiumin Yu , Haoyu Zhang , Yuchen Liu , Hexuan Wang , Ningyi Yang , Yulian Shi , Wanli Zhang , Zijie Wu , Shitong Huang , Wenbin Xie , Ran Duan , Qiuli Mao , Xupeiyao Shi , Zheng Gao , Xiaoning Wang , Hanlin Guo , Lingxiao Chen , Yi Han , Ximing Li , Liyuan Chen , Siqi Tang , Ying Fan , Wenbing Yao , Hong Tian , Xiangdong Gao

Journal: J Control Release

PubMed ID: 39894265

Doi: 10.1016/j.jconrel.2025.01.094

Products & Services: Gene Synthesis