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Impaired Ca Sensitivity of a Novel GCAP1 Variant Causes Cone Dystrophy and Leads to Abnormal Synaptic Transmission Between Photoreceptors and Bipolar Cells

Authors: Valerio Marino, Giuditta Dal Cortivo, Paolo Enrico Maltese, Giorgio Placidi, Elisa De Siena, Benedetto Falsini, Matteo Bertelli, Daniele Dell'Orco

Journal: Int J Mol Sci

PubMed ID: 33919796

Doi: 10.3390/ijms22084030

Products & Services: Plasmid DNA Preparation Gene Synthesis

Infectious Clones Produce SARS-CoV-2 That Causes Severe Pulmonary Disease in Infected K18-Human ACE2 Mice

Authors: Xiang Liu, Ali Zaid, Joseph R Freitas, Nigel A McMillan, Suresh Mahalingam, Adam Taylor

Journal: MBio

PubMed ID: 33879586

Doi: 10.1128/mBio.00819-21

Products & Services: Gene Synthesis

Central Nervous System Barriers Impact Distribution and Expression of iNOS and Arginase-1 in Infiltrating Macrophages During Neuroinflammation

Authors: Daniela C Ivan, Sabrina Walthert, Giuseppe Locatelli

Journal: Front Immunol

PubMed ID: 33936108

Doi: 10.3389/fimmu.2021.666961

Products & Services: Gene Synthesis

Bardet-Biedl syndrome proteins regulate intracellular signaling and neuronal function in patient-specific iPSC-derived neurons

Authors: Liheng Wang, Yang Liu, George Stratigopoulos, Sunil Panigrahi, Lina Sui, Yiying Zhang, Charles A Leduc, Hannah J Glover, Maria Caterina De Rosa, Lisa C Burnett, Damian J Williams, Linshan Shang, Robin Goland, Stephen H Tsang, Sharon Wardlaw, Dieter Egli, Deyou Zheng, Claudia A Doege, Rudolph L Leibel

Journal: J Clin Invest

PubMed ID: 33630762

Doi: 10.1172/JCI146287

Products & Services: Gene Synthesis

The Clinical Significance and Potential Role of Cathepsin S in IgA Nephropathy

Authors: Jingying Zhao, Yongchang Yang, Yubin Wu

Journal: Front Pediatr

PubMed ID: 33912521

Doi: 10.3389/fped.2021.631473

Products & Services: Gene Synthesis

HDAC6 Signaling at Primary Cilia Promotes Proliferation and Restricts Differentiation of Glioma Cells

Authors: Ping Shi, Lan B Hoang-Minh, Jia Tian, Alice Cheng, Reemsha Basrai, Neil Kalaria, Joseph J Lebowitz, Habibeh Khoshbouei, Loic P Deleyrolle, Matthew R Sarkisian

Journal: Cancers (Basel)

PubMed ID: 33915983

Doi: 10.3390/cancers13071644

Products & Services: Gene Synthesis

CRISPR/Cas9 Targeted Mutagenesis for Functional Genetics in Maize

Authors:

Journal: Plants (Basel)

PubMed ID: 33917747

Doi: 10.3390/plants10040723

Products & Services: Gene Synthesis

Mycobacteria In Skin Lesions and the Habitat of the Endangered Houston Toad (Anaxyrus houstonensis)

Authors: Spandana Vemulapally, Andrea Villamizar, Trina Guerra, Maryanne E Tocidlowski, Melissa Spradley, Stan Mays, Michael R J Forstner, Dittmar Hahn

Journal: J Wildl Dis

PubMed ID: 33857294

Doi: 10.7589/JWD-D-20-00145

Products & Services: Gene Synthesis

Design of multi-scale protein complexes by hierarchical building block fusion

Authors: Yang Hsia, Rubul Mout, William Sheffler, Natasha I Edman, Ivan Vulovic, Young-Jun Park, Rachel L Redler, Matthew J Bick, Asim K Bera, Alexis Courbet, Alex Kang, T J Brunette, Una Nattermann, Evelyn Tsai, Ayesha Saleem, Cameron M Chow, Damian Ekiert, Gira Bhabha, David Veesler, David Baker

Journal: Nat Commun

PubMed ID: 33863889

Doi: 10.1038/s41467-021-22276-z

Products & Services: Gene Synthesis

SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation

Authors: David W Sanders, Chanelle C Jumper, Paul J Ackerman, Dan Bracha, Anita Donlic, Hahn Kim, Devin Kenney, Ivan Castello-Serrano, Saori Suzuki, Tomokazu Tamura, Alexander H Tavares, Mohsan Saeed, Alex S Holehouse, Alexander Ploss, Ilya Levental, Florian Douam, Robert F Padera, Bruce D Levy, Clifford P Brangwynne

Journal: Elife

PubMed ID: 33890572

Doi: 10.7554/eLife.65962

Products & Services: Gene Synthesis