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Auxin-salicylic acid seesaw regulates the age-dependent balance between plant growth and herbivore defense
Authors: Wen-Hao Han, Feng-Bin Zhang, Shun-Xia Ji, Kai-Lu Liang, Jun-Xia Wang, Xiao-Ping Fan, Shu-Sheng Liu, Xiao-Wei Wang
Journal: SCIENCE ADVANCES
PubMed ID: 40344064
Doi: 10.1126/sciadv.adu5141
Products & Services: Gene Synthesis   
An intranasal subunit vaccine induces protective systemic and mucosal antibody immunity against respiratory viruses in mouse models
Authors: Aina Karen Anthi, Anette Kolderup, Eline Benno Vaage, Malin Bern, Sopisa Benjakul, Elias Tjärnhage, Fulgencio Ruso-Julve, Kjell-Rune Jensen, Heidrun Elisabeth Lode, Marina Vaysburd, Jeannette Nilsen, Marie Leangen Herigstad, Siri Aastedatter Sakya, Lisa Tietze, Diego Pilati, Mari Nyquist-Andersen, Mirjam Dürkoop, Torleif Tollefsrud Gjølberg, Linghang Peng, Stian Foss, Morten C Moe, Benjamin E Low, Michael V Wiles, David Nemazee, Frode L Jahnsen, John Torgils Vaage, Kenneth A Howard, Inger Sandlie, Leo C James, Gunnveig Grødeland, Fridtjof Lund-Johansen, Jan Terje Andersen
Journal: Nature Communications
PubMed ID: 40312392
Doi: 10.1038/s41467-025-59353-6
Products & Services: Gene Synthesis   
Dual inhibition of DNA-PK and Polϴ boosts precision of diverse prime editing systems
Authors: Louis C Dacquay, Panagiotis Antoniou, Astrid Mentani, Niklas Selfjord, Hanna Mårtensson, Pei-Pei Hsieh, Salman Mustfa, George Thom, Sandra Wimberger, Mike Firth, Nina Akrap, Marcello Maresca, Martin Peterka
Journal: Nature Communications
PubMed ID: 40341582
Doi: 10.1038/s41467-025-59708-z
Products & Services: Gene Synthesis   
Structural determinants of inverted Alu-mediated backsplicing revealed by -MaP and -JuMP
Authors: Justin M Waldern, Colin Taylor, Catherine A Giannetti, Patrick S Irving, Scott R Allen, Mingyi Zhu, Rolf Backofen, Dave Mathews, Kevin M Weeks, Alain Laederach
Journal: Nucleic Acids Research
PubMed ID: 39713457
Doi: 10.1101/2024.12.13.628372
Products & Services: Gene Synthesis   
Mechanistic insights into the stimulation of the histone H3K9 methyltransferase Clr4 by proximal H3K14 ubiquitination
Authors: Yunxiang Du , Maoshen Sun , Zhengqing Li , Xiangwei Wu , Qian Qu , Huasong Ai , Lei Liu
Journal: SCIENCE ADVANCES
PubMed ID: 40446033
Doi: 10.1126/sciadv.adu1864
Products & Services: Gene Synthesis   
CRISPR-Based Environmental Biosurveillance Assisted via Artificial Intelligence Design of Guide-RNAs
Authors: Benjamín Durán-Vinet, Jo-Ann L. Stanton, Gert-Jan Jeunen, Ulla von Ammon, Jackson Treece, Xavier Pochon, Anastasija Zaiko, Neil J. Gemmell
Journal: Environmental DNA
Doi: doi.org/10.1002/edn3.70105
Inhibiting peptidylarginine deiminases (PAD1-4) by targeting a Ca2+ dependent allosteric binding site
Authors: Leslie A Dakin, Li Xing, Justin Hall, Weidong Ding, Felix F Vajdos, Jeffrey W Pelker, Simeon Ramsey, Paul Balbo, Parag V Sahasrabudhe, Mary Ellen Banker, Won Young Choi, Stephen W Wright, Jeanne S Chang, John M Curto, Jennifer E Davoren, Susan E Drozda, Kimberly F Fennell, Kentaro Futatsugi, Steve Kortum, Katherine L Lee, Shenping Liu, Frank Lovering, Jennifer A Nicki, John I Trujillo, Fabien Vincent, Mark E Schnute
Journal: Nature Communications
PubMed ID: 40379660
Doi: 10.1038/s41467-025-59919-4
Products & Services: Gene Synthesis   
Interaction networks of SIM-binding groove mutants reveal alternate modes of SUMO binding and profound impact on SUMO conjugation
Authors: Laura A Claessens, Matty Verlaan-de Vries, Nienke Broekman, Martijn S Luijsterburg, Alfred C O Vertegaal
Journal: SCIENCE ADVANCES
PubMed ID: 40367183
Doi: 10.1126/sciadv.adp2643
Products & Services: Gene Synthesis   
Modular deregulation of central carbon metabolism for efficient xylose utilization in Saccharomyces
Authors: Xiaowei Li, Yanyan Wang, Xin Chen, Leon Eisentraut, Chunjun Zhan, Jens Nielsen, Yun Chen
Journal: Nature Communications
PubMed ID: 40379631
Doi: 10.1038/s41467-025-59966-x
Products & Services: Gene Synthesis   
A FAN1 point mutation associated with accelerated Huntington's disease progression alters its PCNA-mediated assembly on DNA
Authors: Jonas Aretz, Gayathri Jeyasankar, Anna Salerno-Kochan, Maren Thomsen, Gabriel Thieulin-Pardo, Tasir Haque, Edith Monteagudo, Dan Felsenfeld, Michael Finley, Thomas F Vogt, Julien Boudet, Brinda C Prasad
Journal: Nature Communications
PubMed ID: 40368883
Doi: 10.1038/s41467-025-59324-x
Products & Services: Gene Synthesis   
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