目录产品 » IL-4 R alpha/CD124, His, Cynomolgus
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IL-4 R alpha/CD124, His, Cynomolgus

Interleukin 4 Receptor alpha (IL-4 Ra), also known as CD124 and BSF receptor, is a widely expressed 140 kDa transmembrane glycoprotein in the class I cytokine receptor family. The effects of IL-4 are mediated after binding to high affinity receptor complexes present on hematopoietic as well as non-hematopoietic cells.
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Z04844-100

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产品简介
Species Cynomolgus
Protein Construction
IL-4 R alpha/CD124 (Met26-Arg232)
Accession # G7Q0S7		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1 EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA.Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 24.84 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 45-60 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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图例
IL-4 R Alpha/CD124, His, Cynomolgus

Immobilized IL-4 R alpha/CD124, His, Cynomolgus, No Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Cynomolgus IL-4 R alpha, His Tag with the EC50 of 94.4ng/ml determined by ELISA. »

IL-4 R Alpha/CD124, His, Cynomolgus

The purity of IL-4 R alpha/CD124, His, Cynomolgus is greater than 95% as determined by SEC-HPLC. »

IL-4 R Alpha/CD124, His, Cynomolgus

IL-4 R alpha/CD124, His, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

IL-4 R Alpha/CD124, His, Cynomolgus

IL-4 R alpha/CD124, His, Cynomolgus, His Tag immobilized on CM5 Chip can bind Cynomolgus IL-4 R alpha, His Tag with an affinity constant of 13.48 nM as determined in SPR assay (Biacore T200). »

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技术背景
Target Background Interleukin 4 Receptor alpha (IL-4 Ra), also known as CD124 and BSF receptor, is a widely expressed 140 kDa transmembrane glycoprotein in the class I cytokine receptor family. The effects of IL-4 are mediated after binding to high affinity receptor complexes present on hematopoietic as well as non-hematopoietic cells.
Synonyms CD124; IL-4 R alpha; IL-4R subunit alpha; IL4R; IL-4Ra; IL4RACD124
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.