| ￥3500 | |
| Z04844-100 | |
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| Species | Cynomolgus | ||||
| Protein Construction |
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| Purity | > 95% as determined by BisTris PAGE | ||||
| Endotoxin Level | Less than 1 EU per μg by the LAL method. | ||||
| Biological Activity | Measured by its binding ability in a functional ELISA.Test result was comparable to standard batch. | ||||
| Expression System | HEK293 | ||||
| Theoretical Molecular Weight | 24.84 kDa | ||||
| Apparent Molecular Weight | Due to glycosylation, the protein migrates to 45-60 kDa based on Bis-Tris PAGE result. | ||||
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). | ||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||
| Storage & Stability | Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles. |
Immobilized IL-4 R alpha/CD124, His, Cynomolgus, No Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Cynomolgus IL-4 R alpha, His Tag with the EC50 of 94.4ng/ml determined by ELISA. »
The purity of IL-4 R alpha/CD124, His, Cynomolgus is greater than 95% as determined by SEC-HPLC. »
IL-4 R alpha/CD124, His, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »
IL-4 R alpha/CD124, His, Cynomolgus, His Tag immobilized on CM5 Chip can bind Cynomolgus IL-4 R alpha, His Tag with an affinity constant of 13.48 nM as determined in SPR assay (Biacore T200). »
| Target Background | Interleukin 4 Receptor alpha (IL-4 Ra), also known as CD124 and BSF receptor, is a widely expressed 140 kDa transmembrane glycoprotein in the class I cytokine receptor family. The effects of IL-4 are mediated after binding to high affinity receptor complexes present on hematopoietic as well as non-hematopoietic cells. |
| Synonyms | CD124; IL-4 R alpha; IL-4R subunit alpha; IL4R; IL-4Ra; IL4RACD124 |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
