目录产品 » Coagulation Factor III/Tissue Factor, His, Canine
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Coagulation Factor III/Tissue Factor, His, Canine

Tissue factor (also named Coagulation Factor III) is a cell surface glycoprotein responsible for initiating the extrinsic pathway of coagulation.Tissue factor is the primary cellular initiator of blood coagulation via interaction with coagulation factor VII. Aberrant expression of tissue factor is responsible for thrombosis during septic shock, atherosclerosis and cancer.
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产品简介
Species Canine
Protein Construction
Coagulation factor III/Tissue Factor (Thr35-Glu248)
Accession # Q4W6L5		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 25.41 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 35-45 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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图例
Coagulation Factor III/Tissue Factor, His, Canine

The purity of Coagulation Factor III/Tissue Factor, His, Canine is greater than 95% as determined by SEC-HPLC. »

Coagulation Factor III/Tissue Factor, His, Canine

Coagulation Factor III/Tissue Factor, His, Canine on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

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技术背景
Target Background Tissue factor (also named Coagulation Factor III) is a cell surface glycoprotein responsible for initiating the extrinsic pathway of coagulation.Tissue factor is the primary cellular initiator of blood coagulation via interaction with coagulation factor VII. Aberrant expression of tissue factor is responsible for thrombosis during septic shock, atherosclerosis and cancer.
Synonyms Tissue factor; Coagulation Factor III; TF; Thromboplastin; CD142; F3; FLJ17960; TFA
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.