Immobilized Mouse IL-17R alpha, hFc Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for IL-17A/CTLA-8[Biotin], His & Avi, Mouse, His Tag with the EC50 of 28.3 ng/ml determined by ELISA.

IL-17A/CTLA-8[Biotin], His & Avi, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

IL-17A/CTLA-8[Biotin], His & Avi, Mouse

Interleukin‑17A (IL‑17A), also known as CTLA‑8, is a 15‑20 kDa glycosylated cytokine that plays an important role in anti‑microbial and chronic inflammation. The six IL‑17 cytokines (IL‑17A‑F) are encoded by separate genes but adopt a conserved cystine knot fold.IL-17A is a ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines.

产品编号	Z04666
规格	100 μg 500 μg 大单询价
数量
价格	￥5800


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产品简介

Species

Mouse

Protein Construction

IL-17A/CTLA-8 (Ala26-Ala158) Accession # Q62386-1	His	Avi
N-term		C-term

Conjugate

Biotin

Purity

> 95% as determined by Bis-Tris PAGE

Endotoxin Level

Less than 1EU per μg by the LAL method.

Biological Activity

Measured by its binding ability in a functional ELISA. Immobilized Mouse IL17R alpha at 2μg/ml (100μl/well) on the plate can bind IL-17A/CTLA-8[Biotin], His & Avi, Mouse. Test result was comparable to standard batch.

Expression System

HEK293

Theoretical Molecular Weight

18 kDa

Apparent Molecular Weight

Due to glycosylation, the protein migrates to 19-29 kDa based on Bis-Tris PAGE result.

Formulation

Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).

Reconstitution

Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

Storage & Stability

Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

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