目录产品 » Fc gamma RIIIA/CD16a (F176), His & Avi, Human
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Fc gamma RIIIA/CD16a (F176), His & Avi, Human

Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.
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Z04252-100

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产品简介
Species Human
Protein Construction
Fc gamma RIIIA/CD16a (F176) [Gly17-Gln208 (F176)]
Accession # P08637-1		 His Avi
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA.Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 24.7 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 48-58 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from a 0.22 μm filtered solution in PBS, (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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图例
Fc Gamma RIIIA/CD16a (F176), His & Avi, Human

Immobilized Fc gamma RIIIA/CD16a (F176), His & Avi, Human, His Tag at 2 μg/ml (100 μL/well) on the plate. Dose response curve for Anti-Fc gamma RIIIA Antibody, hFc Tag with the EC50 of 9.3 ng/ml determined by ELISA. »

Fc Gamma RIIIA/CD16a (F176), His & Avi, Human

The purity of Fc gamma RIIIA/CD16a (F176), His & Avi, Human is greater than 95% as determined by SEC-HPLC. »

Fc Gamma RIIIA/CD16a (F176), His & Avi, Human

Fc gamma RIIIA/CD16a (F176), His & Avi, Human on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%. »

Fc Gamma RIIIA/CD16a (F176), His & Avi, Human

Fc gamma RIIIA/CD16a (F176), His & Avi, Human , His Tag captured on CM5 Chip via anti-His antibody can bind Rituximab, hFc Tag with an affinity constant of 0.92μM as determined in SPR assay (Biacore T200). »

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技术背景
Target Background Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.
Synonyms Fc gamma RIIIA; FCGR3; FCGR3A; FCGRIII; FcgRIIIA; FcR-10; CD16A; FCG3; IGFR3; FcRIIIa; FcRIII; CD16; IMD20
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.