| ￥3500 | |
| Z03876-100 | |
|
|
|
|
|
|
|
|
|
| Species | Mouse | ||||
| Protein Construction |
|
||||
| Purity |
> 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC |
||||
| Endotoxin Level | Less than 1EU per μg by the LAL method. | ||||
| Biological Activity | Immobilized MSLN/Mesothelin(298-600), His, Mouse(Cat.No.: Z03876) at 2 μg/ml(100μl/Well) on the plate can bind Biotinylated Human CA125, His Tag. | ||||
| Expression System | HEK293 | ||||
| Theoretical Molecular Weight | 35.2 kDa | ||||
| Apparent Molecular Weight | Due to glycosylation, the protein migrates to 35-50 kDa based on Bis-Tris PAGE result. | ||||
| Formulation | Lyophilized from a 0.22 μm filtered solution in PBS, pH 7.4. | ||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||
| Storage & Stability | Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
Immobilized MSLN/Mesothelin(298-600), His, Mouse, His Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Human CA125, His Tag with the EC50 of 21.7 ng/ml determined by ELISA. »
The purity of MSLN/Mesothelin(298-600), His, Mouse is greater than 95% as determined by SEC-HPLC. »
MSLN/Mesothelin(298-600), His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »
| Target Background | Mesothelin, also known as MSLN, is encoded by the MSLN gene. It encodes a precursor protein of 71 kDa that is processed to a 31 kDa shed protein called megakaryocyte potentiating factor (MPF) and a 40 kDa fragment, mesothelin. MSLN is attached to the cell membrane by a glycosyl-phosphatidylinositol (GPI) anchor. It is a differentiation antigen which is highly expressed in several human cancers, including virtually all mesotheliomas and pancreatic adenocarcinomas. |
| Synonyms | MSLN; CAK1 antigen; CAK1; Mesothelin; MPF; MPFSMRP; SMR |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
