SARS-CoV-2 Spike protein (RBD, L452R, Avi & His Tag)

该产品已下架。

SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. Lineage B.1.429, also known as CAL.20C, with S13I, W152C, L452R mutations in the spike proteins, of which the L452R was of particular concern. B.1.429 is possibly more transmissible, but further study is necessary to confirm this. CDC has listed B.1.429 and the related B.1.427 as "variants of concern," and cites a preprint for saying that they exhibit a ~20% increase in viral transmissibility.

产品编号	Z03603
规格	定制报价

联系我们

产品简介

Species

SARS-CoV-2

Protein Construction

Spike RBD [Arg319-Ser591 (L452R)] Accession # P0DTC2	Avi	Poly-His
N-term		C-term

Purity

> 95% as analyzed by SDS-PAGE

Endotoxin Level

< 0.2 EU/μg of protein by gel clotting method

Biological Activity

This protein is validated to bind with human ACE2 in functional ELISA assay.

Expression System

CHO

Theoretical Molecular Weight

33.7 kDa

Formulation

Supplied as a solution in PBS, pH 7.4.

Concentration

Please refer to the COA for the specific lot.

Storage & Stability

Upon receiving, this product remains stable for up to 6 months at -20°C or below. Please avoid repeated freeze-thaw cycles.

技术背景

Target Background	SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. Lineage B.1.429, also known as CAL.20C, with S13I, W152C, L452R mutations in the spike proteins, of which the L452R was of particular concern. B.1.429 is possibly more transmissible, but further study is necessary to confirm this. CDC has listed B.1.429 and the related B.1.427 as "variants of concern," and cites a preprint for saying that they exhibit a ~20% increase in viral transmissibility.
Synonyms	Lineage B.1.429; CAL.20C; B.1.427
References	1. Emergence of a novel SARS-CoV-2 strain in Southern California, USA. 2. New California Variant May Be Driving Virus Surge There, Study Suggests. 3. Neutralization of SARS-CoV-2 Variants B.1.429 and B.1.351.