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目录产品 » Human Recombinant Glucagon-like Peptide 1 Receptor Stable Cell Line
HEK293/CRE-Luc/GLP1R Stable Cell Line

Concentration-dependent stimulation of intracellular cAMP (Luciferase reportor) by GLP-1(7-37) in HEK293/CRE-Luc/GLP1R cells

HEK293/CRE-Luc/GLP1R Stable Cell Line

Concentration-dependent stimulation of intracellular cAMP (Luciferase reportor) by GLP-1(7-37) in HEK293/CRE-Luc/GLP1R cells

HEK293/CRE-Luc/GLP1R Stable Cell Line

Concentration-dependent stimulation of intracellular cAMP (Luciferase reportor) by GLP-1(7-37) in HEK293/CRE-Luc/GLP1R cells

HEK293/CRE-Luc/GLP1R Stable Cell Line

GLP1R binds specifically the glucagon-like peptide-1 (GLP1) and has much lower affinity for related peptides such as the gastric inhibitory polypeptide and glucagon. GLP1R is known to be expressed in pancreatic beta cells. Activated GLP1R stimulates the adenylyl cyclase pathway which results in increased insulin synthesis and release of insulin. Consequently, GLP1R has been suggested as a potential target for the treatment of diabetes. GLP1R is also expressed in the brain where it is involved in the control of appetite. Furthermore, mice which over express GLP1R display improved memory and learning.
M00562
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Applications Functional assays for GLP1R receptor

Storage Liquid nitrogen immediately upon delivery
Species human
稳定性 16 passages

Freeze Medium 72% DMEM, 20% FBS, 8% DMSO
Culture Medium DMEM, 10% FBS, 400 μg/ml G418, 200 μg/ml HygromycinB

  • HEK293/CRE-Luc/GLP1R Stable Cell Line
  • HEK293/CRE-Luc/GLP1R Stable Cell Line

    Concentration-dependent stimulation of intracellular cAMP (Luciferase reportor) by GLP-1(7-37) in HEK293/CRE-Luc/GLP1R cells

  • HEK293/CRE-Luc/GLP1R Stable Cell Line
  • HEK293/CRE-Luc/GLP1R Stable Cell Line

    Concentration-dependent stimulation of intracellular cAMP (Luciferase reportor) by GLP-1(7-37) in HEK293/CRE-Luc/GLP1R cells

  • HEK293/CRE-Luc/GLP1R Stable Cell Line
  • HEK293/CRE-Luc/GLP1R Stable Cell Line

    Concentration-dependent stimulation of intracellular cAMP (Luciferase reportor) by GLP-1(7-37) in HEK293/CRE-Luc/GLP1R cells