Recombinant Cas9-based fusion with double-ended NLS expressed by E.coli
描述
ABE8e is an innovative adenine base editor designed to enable precise genetic modifications by converting A-T base pairs to G-C base pairs without introducing double-stranded breaks or requiring donor DNA templates.
ABE8e contains eight additional mutations in the TadA domain, augments the effectiveness and applicability of adenine base editing.
