Isotype control antibodies are used to estimate the nonspecific binding of target primary antibodies due to Fc receptor binding or other protein-protein interactions. An isotype control antibody should have the same immunoglobulin type and be used at the same concentration as the test antibody.
Serum Amyloid A (SAA) is an acute-phase protein. The concentration of SAA in blood increases rapidly when tissue damage or inflammation occurs. It is considered as an early biomarker for the diagnosis of many inflammatory diseases. SAA can also be used as an important indicator of infection.