GenScript - Make Research Easy - The leader in molecular cloning and gene synthesis, peptide synthesis,protein and antibody engineering.

A new TROP2-targeting antibody-drug conjugate shows potent antitumor efficacy in breast and lung cancers

Authors: Dan-Dan Zhou, Xiao-Tian Zhai, Lan-Wen Zhang, Zi-Hui Xie, Ying Wang, Yong-Su Zhen, Rui-Juan Gao, Qing-Fang Miao

Journal: NPJ Precis Oncol

PubMed ID: 38654141

Doi: 10.1038/s41698-024-00584-z

Products & Services: Proteins, Expression, Isolation and Analysis

Phylogenetic conservation of Trop-2 across species-rodent and primate genomics model anti-Trop-2 therapy for pre-clinical benchmarks

Authors: Emanuela Guerra, Marco Trerotola, Valeria Relli, Rossano Lattanzio, Khouloud Boujnah, Nicole Travali, Antonino Moschella, Paolo Todaro, Laura Pierdomenico, Roberta Di Pietro, Nicola Tinari, Saverio Alberti

Journal: Front Genet

PubMed ID: 38250577

Doi: 10.3389/fgene.2023.1297367

Products & Services: Gene Synthesis

TROP2 Down-regulated DSG2 to Promote Gastric Cancer Cell Invasion and Migration by EGFR/AKT and DSG2/PG/β-Catenin Pathways

Authors: Tingting Yang, Lizhou Jia, Susu Bian, Xinxia Chang, Qian Zhang, Qi Tang, Jing Zhu, Zhiping Yang, Zhenqing Feng

Journal: Curr Cancer Drug Targets

PubMed ID: 35392784

Doi: 10.2174/1568009622666220407111013

Products & Services: Proteins, Expression, Isolation and Analysis

TROP2 increases growth and metastasis of human oral squamous cell carcinoma through activation of the PI3K/Akt signaling pathway.

Authors: Tang G, Tang Q, Jia L, Chen Y, Lin L, Kuai X, Gong A, Feng Z.

Journal: Int J Mol Med

PubMed ID: 31638186

Doi: 10.3892/ijmm.2019.4378

Products & Services: Gene Synthesis

Trop2 is a potential biomarker for the promotion of EMT in human breast cancer.

Authors: ZhaoWei，KuaiXingwang，ZhouXueyi，JiaLizhou，WangJinsong，YangXiaobing，TianZhidan，WangXiaolei，LvQian，WangBin，ZhaoYoucai，HuangWe

Journal: Oncol. Rep.

PubMed ID: 29901160

Doi: 10.3892/or.2018.6496

Products & Services: DNA Sequencing

Pigment epithelium-derived factor (PEDF) peptide promotes the expansion of hepatic stem/progenitor cells via ERK and STAT3-dependent signaling.

Authors: Shih SC,Ho TC,Chen SL,Tsao YP.

Journal: Am J Transl Res.

PubMed ID: 28386338

Products & Services: Peptide Synthesis

Rapid Fine Conformational Epitope Mapping Using Comprehensive Mutagenesis and Deep Sequencing.

Authors: Kowalsky CA, Faber MS, Nath A, Dann HE, Kelly VW, Liu L, Shanker P, Wagner EK, Maynard JA, Chan C, Whitehead TA.

Journal: J Biol Chem. 290(44):26457-70

Products & Services: Peptide Synthesis

Rapid fine conformational epitope mapping using comprehensive mutagenesis and deep sequencing

Authors: Caitlin A Kowalsky, Matthew S Faber, Aritro Nath, Hailey E Dann, Vince W Kelly, Li Liu, Purva Shanker, Ellen K Wagner, Jennifer A Maynard, Christina Chan, Timothy A Whitehead

Journal: J Biol Chem

PubMed ID: 26296891

Doi: 10.1074/jbc.M115.676635

Products & Services: Monoclonal Antibody Services

A novel human Fab antibody for Trop2 inhibits breast cancer growth in vitro and in vivo.

Authors: Lin H, Zhang H, Wang J, Lu M, Zheng F, Wang C, Tang X, Xu N, Chen R, Zhang D, Zhao P, Zhu J, Mao Y, Feng Z.

Journal: Int J Cancer.

PubMed ID: 23982827

Products & Services: Monoclonal Antibody Services

全部

资源中心

技术支持

关于我们